Protein: 2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PP2A B subunit isoform B'-alpha) (PP2A B subunit isoform B56-alpha) (PP2A B subunit isoform PR61-alpha) (PR61alpha) (PP2A B subunit isoform R5-alpha)

Gene: 2A5A, PPP2R5A
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q15172

Gene Ontology (top 5):
GO:0000159 - protein phosphatase type 2A complex
GO:0000775 - chromosome, centromeric region
GO:0004721 - phosphoprotein phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

930853

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

10

20

Small-scale

0.978

High

672129

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

7

20

Small-scale

0.972

High

672425

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

5

20

Small-scale

0.931

High

915194

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

4

20

High-throughput

0.903

High

1032366

2A5G
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

2

8

Small-scale

0.754

High

339244

MOS
Proto-oncogene serine/threonine-protein kinase mos

5

1

High-throughput

0.717

High

1069246

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

1

8

High-throughput

0.691

High

170658

AXIN1
Axin-1

3

2

Small-scale

0.681

High

236933

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

3

6

Small-scale

0.679

High

881857

WNT3A
Protein Wnt-3a

3

4

High-throughput

0.667

High

1069249

SGO1
Shugoshin 1

3

4

Small-scale

0.660

High

1069259

DZIP1
Cilium assembly protein DZIP1

3

9

Small-scale

0.650

High

1069248

SGO2
Shugoshin 2

2

2

Small-scale

0.625

High

331292

CHK2
Serine/threonine-protein kinase Chk2

2

6

Small-scale

0.625

High

1069261

FA43A
Protein FAM43A

3

4

High-throughput

0.609

High

1069269

CA021
Uncharacterized protein C1orf21

3

2

High-throughput

0.607

High

1025288

LIPA1
Liprin-alpha-1

2

4

High-throughput

0.606

High

1069262

USBP1
Harmonin-binding protein USHBP1

2

1

High-throughput

0.606

High

1069278

AXIN2
Axin-2

2

2

High-throughput

0.606

High

585478

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

2

4

Small-scale

0.595

High

1058666

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

8

Small-scale

0.590

High

1017385

CDC20
Cell division cycle protein 20 homolog

2

2

Small-scale

0.584

High

799449

TNNT2
Troponin T, cardiac muscle

2

0

High-throughput

0.580

High

1069274

SHFL
Shiftless antiviral inhibitor of ribosomal frameshifting protein

2

0

High-throughput

0.580

High

1069268

PRR14
Proline-rich protein 14

2

3

High-throughput

0.574

High

1069267

GNL3
Guanine nucleotide-binding protein-like 3

1

0

Small-scale

0.549

High

862043

DAPK1
Death-associated protein kinase 1

1

0

Small-scale

0.537

High

302646

FA13A
Protein FAM13A

1

4

High-throughput

0.536

High

639909

ITB7
Integrin beta-7

1

1

High-throughput

0.536

High

800387

CBX5
Chromobox protein homolog 5

1

2

Small-scale

0.536

High

960437

CDK17
Cyclin-dependent kinase 17

1

3

High-throughput

0.536

High

1069263

ARHG2
Rho guanine nucleotide exchange factor 2

1

3

High-throughput

0.536

High

1069265

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

2

High-throughput

0.536

High

1069271

RNF41
E3 ubiquitin-protein ligase NRDP1

1

2

High-throughput

0.536

High

1069272

PKHA5
Pleckstrin homology domain-containing family A member 5

1

5

High-throughput

0.536

High

1069276

KLH14
Kelch-like protein 14

1

3

High-throughput

0.536

High

1069279

MTCL1
Microtubule cross-linking factor 1

1

4

High-throughput

0.536

High

1069280

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

3

High-throughput

0.536

High

1069282

PPME1
Protein phosphatase methylesterase 1

1

1

High-throughput

0.536

High

560064

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

Small-scale

0.529

High

801704

RAGP1
Ran GTPase-activating protein 1

1

1

High-throughput

0.515

High

394744

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.515

High

346835

MYC
Myc proto-oncogene protein

1

0

Small-scale

0.513

High

1069253

CDCA2
Cell division cycle-associated protein 2

1

1

High-throughput

0.501

High

1069266

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

2

Small-scale

0.501

High

1069257

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

301294

MTCL2
Microtubule cross-linking factor 2

1

4

High-throughput

0.489

High

1069250

NHSL1
NHS-like protein 1

1

6

High-throughput

0.489

High

1069251

MTCL3
Microtubule cross-linking factor 3

1

4

High-throughput

0.489

High

1069256

KNDC1
Kinase non-catalytic C-lobe domain-containing protein 1

1

7

High-throughput

0.489

High

1069277

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

2

High-throughput

0.489

High

1069281

CRBG1
Beta/gamma crystallin domain-containing protein 1

1

6

High-throughput

0.489

High

1069264

NEK1
Serine/threonine-protein kinase Nek1

1

4

Small-scale

0.481

High

330201

PTTG1
Securin

1

0

Small-scale

0.480

High

227507

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

319203

BRD1
Bromodomain-containing protein 1

1

1

High-throughput

0.479

High

672837

CDC27
Cell division cycle protein 27 homolog

1

2

Small-scale

0.479

High

679108

TLX1
T-cell leukemia homeobox protein 1

1

1

Small-scale

0.479

High

963820

SET
Protein SET

1

1

Small-scale

0.479

High

1069252

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

1

Small-scale

0.479

High

1069255

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

1069270

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.479

High

1069273

SP110
Sp110 nuclear body protein

1

2

High-throughput

0.479

High

1069275

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.479

High

489423

BCL2
Apoptosis regulator Bcl-2

1

0

Small-scale

0.458

High

1069247

UBE2S
Ubiquitin-conjugating enzyme E2 S

1

0

Small-scale

0.458

High

1069254

FAP20
Fanconi anemia core complex-associated protein 20

1

0

Small-scale

0.458

High

1069258

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1069260

KSR1
Kinase suppressor of Ras 1

1

5

Small-scale

0.445

High

600577

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.438

High

988895

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.438

High

1056788

ESPL1
Separin

1

0

Small-scale

0.426

High

62703

ERIC4
Glutamate-rich protein 4

2

0

High-throughput

0.316

High


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Last updated: 15 Jul 2024