Protein: CYTB
Cystatin-B (CPI-B) (Liver thiol proteinase inhibitor) (Stefin-B)

Gene: CYTB, CSTB
Organism: Homo sapiens
Interactions: 87
UniProt ID: P04080

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0003723 - RNA binding
GO:0004866 - endopeptidase inhibitor activity
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

376060

CATB
Cathepsin B

3

7

Small-scale

0.840

High

376061

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

2

6

Small-scale

0.799

High

376059

CATL1
Procathepsin L

1

6

High-throughput

0.691

High

376074

CATO
Cathepsin O

1

8

High-throughput

0.691

High

376119

CATF
Cathepsin F

1

8

High-throughput

0.691

High

376110

LGMN
Legumain

1

1

Small-scale

0.647

High

344813

CYTC
Cystatin-C

1

0

Small-scale

0.614

High

376065

CFTR
Cystic fibrosis transmembrane conductance regulator

2

1

High-throughput

0.601

High

376093

RHG31
Rho GTPase-activating protein 31

2

2

High-throughput

0.571

High

376116

RHG35
Rho GTPase-activating protein 35

2

2

High-throughput

0.571

High

376081

H31
Histone H3.1

2

0

Small-scale

0.559

High

170204

TIF1A
Transcription intermediary factor 1-alpha

1

2

High-throughput

0.536

High

376087

CUL3
Cullin-3

1

2

High-throughput

0.536

High

376102

PDK1L
Serine/threonine-protein kinase PDIK1L

1

1

High-throughput

0.536

High

376122

AURKC
Aurora kinase C

1

1

High-throughput

0.536

High

376071

VHL
von Hippel-Lindau disease tumor suppressor

1

1

High-throughput

0.515

High

376070

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

High-throughput

0.513

High

376107

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.513

High

376118

IRAK4
Interleukin-1 receptor-associated kinase 4

1

0

High-throughput

0.513

High

208086

SPY2
Protein sprouty homolog 2

1

1

High-throughput

0.508

High

224263

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.508

High

376073

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

376084

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

0

High-throughput

0.493

High

376115

ECT2
Protein ECT2

1

1

High-throughput

0.481

High

243777

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

345651

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

376057

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.479

High

376066

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

376075

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

376086

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

376090

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.479

High

376094

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

376095

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.479

High

376101

SLX4
Structure-specific endonuclease subunit SLX4

1

2

High-throughput

0.479

High

376105

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.479

High

376109

RUFY1
RUN and FYVE domain-containing protein 1

1

1

High-throughput

0.479

High

376114

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

376125

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.479

High

62718

DDTL
D-dopachrome decarboxylase-like protein

1

0

High-throughput

0.458

High

119071

LEG9
Galectin-9

1

0

High-throughput

0.458

High

226225

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

259999

TBCA
Tubulin-specific chaperone A

1

0

High-throughput

0.458

High

298038

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

302766

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

324156

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

351880

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

354245

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

376063

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

376064

EPB41
Protein 4.1

1

0

High-throughput

0.458

High

376067

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

376068

PTBP1
Polypyrimidine tract-binding protein 1

1

0

High-throughput

0.458

High

376069

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

0

High-throughput

0.458

High

376072

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.458

High

376076

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

High-throughput

0.458

High

376077

MTPN
Myotrophin

1

0

High-throughput

0.458

High

376078

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

376079

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

376080

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.458

High

376082

CYC
Cytochrome c

1

0

High-throughput

0.458

High

376083

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

376085

PRDM2
PR domain zinc finger protein 2

1

0

High-throughput

0.458

High

376088

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

376089

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

376091

CCDC6
Coiled-coil domain-containing protein 6

1

0

High-throughput

0.458

High

376092

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

376097

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

376098

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

376099

DET1
DET1 homolog

1

0

High-throughput

0.458

High

376100

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

376103

NUP43
Nucleoporin Nup43

1

0

High-throughput

0.458

High

376104

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

376106

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.458

High

376108

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

376111

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.458

High

376117

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

376120

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

376121

DS13B
Dual specificity protein phosphatase 13B

1

0

High-throughput

0.458

High

376123

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.458

High

305887

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

4

High-throughput

0.445

High

376058

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

376112

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

4

High-throughput

0.445

High

376113

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

4

High-throughput

0.445

High

204910

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

200467

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.426

High

376062

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

376096

LIN54
Protein lin-54 homolog

1

0

Small-scale

0.426

High

376124

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024