Protein: CP2C9
Cytochrome P450 2C9 (EC 1.14.14.1) ((R)-limonene 6-monooxygenase) (EC 1.14.14.53) ((S)-limonene 6-monooxygenase) (EC 1.14.14.51) ((S)-limonene 7-monooxygenase) (EC 1.14.14.52) (CYPIIC9) (Cholesterol 25-hydroxylase) (Cytochrome P-450MP) (Cytochrome P450 MP-4) (Cytochrome P450 MP-8) (Cytochrome P450 PB-1) (S-mephenytoin 4-hydroxylase)

Gene: CP2C9, CYP2C9
Organism: Homo sapiens
Interactions: 103
UniProt ID: P11712

Gene Ontology (top 5):
GO:0004497 - monooxygenase activity
GO:0005506 - iron ion binding
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

514669

CP2CI
Cytochrome P450 2C18

3

12

High-throughput

0.861

High

514663

NCPR
NADPH--cytochrome P450 reductase

3

6

Small-scale

0.840

High

514670

CP2CJ
Cytochrome P450 2C19

2

12

High-throughput

0.811

High

443994

CP3A4
Cytochrome P450 3A4

1

11

Small-scale

0.647

High

496153

CP2D6
Cytochrome P450 2D6

1

12

Small-scale

0.647

High

514672

AGRE5
Adhesion G protein-coupled receptor E5

2

2

High-throughput

0.628

High

514739

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

4

High-throughput

0.541

High

317704

STABP
STAM-binding protein

1

0

High-throughput

0.518

High

320119

RAB3D
Ras-related protein Rab-3D

1

0

High-throughput

0.518

High

514690

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.518

High

514722

RNF32
RING finger protein 32

1

1

High-throughput

0.494

High

514691

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

0

High-throughput

0.493

High

514737

SSRG
Translocon-associated protein subunit gamma

1

0

High-throughput

0.493

High

514719

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

2

High-throughput

0.481

High

123476

PGRC1
Membrane-associated progesterone receptor component 1

1

9

High-throughput

0.479

High

170783

PGRC2
Membrane-associated progesterone receptor component 2

1

9

High-throughput

0.479

High

180800

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.479

High

263152

SC22B
Vesicle-trafficking protein SEC22b

1

1

High-throughput

0.479

High

276414

FACE1
CAAX prenyl protease 1 homolog

1

1

High-throughput

0.479

High

299622

SUN1
SUN domain-containing protein 1

1

1

High-throughput

0.479

High

310484

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.479

High

514665

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.479

High

514666

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

3

High-throughput

0.479

High

514668

HMOX2
Heme oxygenase 2

1

1

High-throughput

0.479

High

514677

S12A2
Solute carrier family 12 member 2

1

1

High-throughput

0.479

High

514679

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

514685

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.479

High

514686

ITPR2
Inositol 1,4,5-trisphosphate receptor type 2

1

1

High-throughput

0.479

High

514687

ITPR3
Inositol 1,4,5-trisphosphate receptor type 3

1

1

High-throughput

0.479

High

514689

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

2

High-throughput

0.479

High

514701

VRK2
Serine/threonine-protein kinase VRK2

1

4

High-throughput

0.479

High

514703

LRC49
Leucine-rich repeat-containing protein 49

1

1

High-throughput

0.479

High

514706

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.479

High

514710

UBXN4
UBX domain-containing protein 4

1

1

High-throughput

0.479

High

514715

DNJC1
DnaJ homolog subfamily C member 1

1

2

High-throughput

0.479

High

514720

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

514724

WDR41
WD repeat-containing protein 41

1

1

High-throughput

0.479

High

514726

SEC12
Guanine nucleotide-exchange factor SEC12

1

2

High-throughput

0.479

High

514731

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.479

High

514732

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.479

High

514733

STIM2
Stromal interaction molecule 2

1

1

High-throughput

0.479

High

514734

STX18
Syntaxin-18

1

1

High-throughput

0.479

High

514741

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

4

High-throughput

0.479

High

62744

TBAL3
Tubulin alpha chain-like 3

1

0

High-throughput

0.458

High

126752

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.458

High

165152

PLXB2
Plexin-B2

1

0

High-throughput

0.458

High

235327

ADCY9
Adenylate cyclase type 9

1

0

High-throughput

0.458

High

242804

TRI13
E3 ubiquitin-protein ligase TRIM13

1

0

High-throughput

0.458

High

263998

TACC1
Transforming acidic coiled-coil-containing protein 1

1

0

High-throughput

0.458

High

307585

STBD1
Starch-binding domain-containing protein 1

1

0

High-throughput

0.458

High

316563

ACSL3
Fatty acid CoA ligase Acsl3

1

0

High-throughput

0.458

High

390042

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

438673

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.458

High

514667

CALX
Calnexin

1

0

High-throughput

0.458

High

514673

CAMLG
Guided entry of tail-anchored proteins factor CAMLG

1

0

High-throughput

0.458

High

514674

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

514675

EMD
Emerin

1

0

High-throughput

0.458

High

514676

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

0

High-throughput

0.458

High

514681

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

514682

STX5
Syntaxin-5

1

0

High-throughput

0.458

High

514684

PHLP
Phosducin-like protein

1

0

High-throughput

0.458

High

514688

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

514693

TGO1
Transport and Golgi organization protein 1 homolog

1

0

High-throughput

0.458

High

514695

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

0

High-throughput

0.458

High

514697

TPGS1
Tubulin polyglutamylase complex subunit 1

1

0

High-throughput

0.458

High

514698

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

514699

KTN1
Kinectin

1

0

High-throughput

0.458

High

514700

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.458

High

514702

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

0

High-throughput

0.458

High

514704

TM199
Transmembrane protein 199

1

0

High-throughput

0.458

High

514708

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.458

High

514709

SYNE2
Nesprin-2

1

0

High-throughput

0.458

High

514711

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.458

High

514712

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

514714

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

514716

TRPM7
Transient receptor potential cation channel subfamily M member 7

1

0

High-throughput

0.458

High

514717

CLCC1
Chloride channel CLIC-like protein 1

1

0

High-throughput

0.458

High

514721

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.458

High

514725

VEZA
Vezatin

1

0

High-throughput

0.458

High

514727

AT131
Endoplasmic reticulum transmembrane helix translocase

1

0

High-throughput

0.458

High

514728

JPH1
Junctophilin-1

1

0

High-throughput

0.458

High

514730

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

High-throughput

0.458

High

514735

DHCR7
7-dehydrocholesterol reductase

1

0

High-throughput

0.458

High

514738

FND3A
Fibronectin type-III domain-containing protein 3A

1

0

High-throughput

0.458

High

514742

SRPRB
Signal recognition particle receptor subunit beta

1

0

High-throughput

0.458

High

514743

S23IP
SEC23-interacting protein

1

0

High-throughput

0.458

High

514664

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.437

High

514692

RABL3
Rab-like protein 3

1

1

High-throughput

0.437

High

514713

FAF2
FAS-associated factor 2

1

1

High-throughput

0.437

High

330628

TOM40
Mitochondrial import receptor subunit TOM40 homolog

2

0

High-throughput

0.328

High

514671

STA5A
Signal transducer and activator of transcription 5A

1

0

High-throughput

0.251

Low

514678

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

High-throughput

0.249

Low

514680

RBM11
Splicing regulator RBM11

1

0

High-throughput

0.249

Low

514683

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

0

High-throughput

0.249

Low

514694

TOIP1
Torsin-1A-interacting protein 1

1

0

High-throughput

0.249

Low

514696

ZCHC8
Zinc finger CCHC domain-containing protein 8

1

0

High-throughput

0.249

Low

514705

MACOI
Macoilin

1

0

High-throughput

0.249

Low

514707

NPL4
Nuclear protein localization protein 4 homolog

1

0

High-throughput

0.249

Low

514718

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

High-throughput

0.249

Low

514723

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

0

High-throughput

0.249

Low

514729

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

0

High-throughput

0.249

Low

514736

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.249

Low

514740

MAN1
Inner nuclear membrane protein Man1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024