Protein: JIP2
C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)

Gene: JIP2, MAPK8IP2
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q13387

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001540 - amyloid-beta binding
GO:0001662 - behavioral fear response
GO:0005078 - MAP-kinase scaffold activity
GO:0005198 - structural molecule activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

338374

EGFR
Epidermal growth factor receptor

4

20

High-throughput

0.887

High

1032958

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

3

11

Small-scale

0.879

High

171494

UBD
Ubiquitin D

2

10

High-throughput

0.819

High

394667

A4
Amyloid-beta precursor protein

2

6

Small-scale

0.754

High

833590

NUMB
Protein numb homolog

2

3

High-throughput

0.743

High

972457

M3K10
Mitogen-activated protein kinase kinase kinase 10

1

16

Small-scale

0.724

High

1018208

M3K12
Mitogen-activated protein kinase kinase kinase 12

1

20

Small-scale

0.724

High

1032911

M3K11
Mitogen-activated protein kinase kinase kinase 11

1

11

Small-scale

0.724

High

899626

FGF12
Fibroblast growth factor 12

4

8

Small-scale

0.685

High

1032936

FGF13
Fibroblast growth factor 13

4

8

Small-scale

0.685

High

1032957

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

3

10

Small-scale

0.670

High

1032901

ASPP2
Apoptosis-stimulating of p53 protein 2

1

9

High-throughput

0.656

High

1032909

ITSN1
Intersectin-1

1

12

High-throughput

0.656

High

153120

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

2

15

Small-scale

0.629

High

1021393

ANK3
Ankyrin-3

1

8

High-throughput

0.618

High

1022387

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

8

Small-scale

0.618

High

1032899

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

14

Small-scale

0.618

High

1032947

DUS16
Dual specificity protein phosphatase 16

2

4

Small-scale

0.611

High

678910

HXC8
Homeobox protein Hox-C8

3

20

High-throughput

0.607

High

124508

TULP2
Tubby-related protein 2

2

0

High-throughput

0.602

High

1032902

LRP8
Low-density lipoprotein receptor-related protein 8

2

20

Small-scale

0.594

High

173885

MK13
Mitogen-activated protein kinase 13

2

12

Small-scale

0.584

High

805408

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

13

Small-scale

0.584

High

1032907

ANGP1
Angiopoietin-1

2

5

High-throughput

0.579

High

383782

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.579

High

1032908

TRBP2
RISC-loading complex subunit TARBP2

2

3

High-throughput

0.576

High

1032929

DUS18
Dual specificity protein phosphatase 18

2

4

High-throughput

0.576

High

1032945

RBM4
RNA-binding protein 4

2

2

High-throughput

0.576

High

1032935

RPGF5
Rap guanine nucleotide exchange factor 5

2

3

High-throughput

0.574

High

800883

MK09
Mitogen-activated protein kinase 9

1

12

Small-scale

0.561

High

957599

LRP2
Low-density lipoprotein receptor-related protein 2

2

20

Small-scale

0.556

High

1032931

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

20

Small-scale

0.553

High

429031

ADRB2
Beta-2 adrenergic receptor

1

1

Small-scale

0.552

High

837006

MRE11
Double-strand break repair protein MRE11

2

0

High-throughput

0.551

High

905380

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

2

0

High-throughput

0.551

High

1032925

MSRB3
Methionine-R-sulfoxide reductase B3

2

0

High-throughput

0.551

High

1032927

RYBP
RING1 and YY1-binding protein

2

0

High-throughput

0.551

High

1032916

RBG1L
Rab GTPase-activating protein 1-like

1

0

High-throughput

0.546

High

1032915

TM128
Transmembrane protein 128

2

1

High-throughput

0.542

High

1032918

CV039
Synaptic plasticity regulator PANTS

2

3

High-throughput

0.542

High

380995

SEMG1
Semenogelin-1

1

1

High-throughput

0.536

High

1032926

ASPM
Abnormal spindle-like microcephaly-associated protein

1

2

High-throughput

0.536

High

1032937

FGF11
Fibroblast growth factor 11

1

8

High-throughput

0.536

High

1032938

FGF14
Fibroblast growth factor 14

1

8

High-throughput

0.536

High

992661

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

20

Small-scale

0.527

High

155841

SH21B
SH2 domain-containing protein 1B

2

14

High-throughput

0.526

High

321398

LSM8
U6 snRNA-associated Sm-like protein LSm8

2

2

High-throughput

0.526

High

781733

MNDA
Myeloid cell nuclear differentiation antigen

2

1

High-throughput

0.526

High

1032904

GALT3
Polypeptide N-acetylgalactosaminyltransferase 3

2

2

High-throughput

0.526

High

1032920

SPSB3
SPRY domain-containing SOCS box protein 3

2

7

High-throughput

0.526

High

1032943

SCLT1
Sodium channel and clathrin linker 1

2

7

High-throughput

0.526

High

1032944

ZN670
Zinc finger protein 670

2

3

High-throughput

0.526

High

1032946

C1QT3
Complement C1q tumor necrosis factor-related protein 3

2

6

High-throughput

0.526

High

1032951

RPA12
DNA-directed RNA polymerase I subunit RPA12

2

1

High-throughput

0.526

High

1032956

ING4
Inhibitor of growth protein 4

2

2

High-throughput

0.526

High

403872

ITB1
Integrin beta-1

1

15

High-throughput

0.515

High

535386

GFAP
Glial fibrillary acidic protein

1

8

High-throughput

0.515

High

568650

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

9

High-throughput

0.515

High

655354

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

5

High-throughput

0.515

High

925248

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.515

High

1032959

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

2

High-throughput

0.515

High

590894

BTF3
Transcription factor BTF3

1

0

High-throughput

0.513

High

1032919

INT5
Integrator complex subunit 5

1

0

High-throughput

0.513

High

690144

GBP2
Guanylate-binding protein 2

1

1

High-throughput

0.508

High

1017110

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

High-throughput

0.508

High

1032923

RAI1
Retinoic acid-induced protein 1

1

6

High-throughput

0.508

High

1032932

SYNE2
Nesprin-2

1

3

High-throughput

0.508

High

1032939

KIFC2
Kinesin-like protein KIFC2

1

4

High-throughput

0.508

High

1032952

KS6B2
Ribosomal protein S6 kinase beta-2

1

7

High-throughput

0.508

High

864862

MK10
Mitogen-activated protein kinase 10

1

12

Small-scale

0.501

High

1032924

VRK2
Serine/threonine-protein kinase VRK2

1

7

Small-scale

0.501

High

1032934

RSPH1
Radial spoke head 1 homolog

1

1

High-throughput

0.494

High

544968

AMPN
Aminopeptidase N

1

0

High-throughput

0.493

High

667459

CASP1
Caspase-1

1

0

High-throughput

0.493

High

713088

SDC2
Syndecan-2

1

0

High-throughput

0.493

High

970618

SEMG2
Semenogelin-2

1

1

High-throughput

0.489

High

1032905

TTLL4
Tubulin monoglutamylase TTLL4

1

1

High-throughput

0.489

High

1032906

RRP5
Protein RRP5 homolog

1

2

High-throughput

0.489

High

1032941

SENP5
Sentrin-specific protease 5

1

1

High-throughput

0.489

High

131144

ZN593
Zinc finger protein 593

1

0

High-throughput

0.486

High

618070

COF1
Cofilin-1

1

0

High-throughput

0.486

High

874895

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.486

High

921247

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.486

High

1032912

FSCN1
Fascin

1

0

High-throughput

0.486

High

1032922

ASGL1
Isoaspartyl peptidase/L-asparaginase

1

0

High-throughput

0.486

High

1032948

VP33B
Vacuolar protein sorting-associated protein 33B

1

0

High-throughput

0.486

High

1032950

YYAP1
YY1-associated protein 1

1

0

High-throughput

0.486

High

1032917

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

Small-scale

0.479

High

1032953

FBW1B
F-box/WD repeat-containing protein 11

1

6

High-throughput

0.479

High

551047

CHIN
N-chimaerin

1

3

High-throughput

0.464

High

850467

PLXA3
Plexin-A3

1

3

High-throughput

0.464

High

1032910

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

High-throughput

0.464

High

1032928

ZN784
Zinc finger protein 784

1

5

High-throughput

0.464

High

1032942

MAGD4
Melanoma-associated antigen D4

1

5

High-throughput

0.464

High

1032954

ERG28
Ergosterol biosynthetic protein 28 homolog

1

1

High-throughput

0.464

High

1032914

Q53HF2
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.462

High

488208

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

1

High-throughput

0.439

High

285175

O78179
HLA class I histocompatibility antigen, C alpha chain

1

1

High-throughput

0.417

High

63232

IGIP
IgA-inducing protein homolog

2

0

High-throughput

0.310

High

1032949

CH033
UPF0488 protein C8orf33

2

0

High-throughput

0.310

High

124488

LFTY2
Left-right determination factor 2

2

0

High-throughput

0.300

High

362388

CRP

2

0

High-throughput

0.300

High

372862

SLPI
Antileukoproteinase

2

0

High-throughput

0.300

High

447939

SRP19
Signal recognition particle 19 kDa protein

2

0

High-throughput

0.300

High

589709

ISK2
Serine protease inhibitor Kazal-type 2

2

0

High-throughput

0.300

High

1032933

CTBL1
Beta-catenin-like protein 1

2

0

High-throughput

0.300

High

1032940

S39AD
Zinc transporter ZIP13

2

0

High-throughput

0.300

High

1032955

APC10
Anaphase-promoting complex subunit 10

2

0

High-throughput

0.300

High

81710

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

0

High-throughput

0.288

High

304543

PRS23
Serine protease 23

1

0

High-throughput

0.282

High

658356

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.279

Low

1032913

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

1032921

INT8
Integrator complex subunit 8

1

0

High-throughput

0.279

Low

261818

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.265

Low

822574

MASP1
Mannan-binding lectin serine protease 1

1

0

High-throughput

0.265

Low

856177

SPSY
Spermine synthase

1

0

High-throughput

0.265

Low

1032900

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.265

Low

1032903

DPYL1
Dihydropyrimidinase-related protein 1

1

0

High-throughput

0.265

Low

1032930

BBS10
Bardet-Biedl syndrome 10 protein

1

0

High-throughput

0.265

Low

1032960

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.265

Low


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Last updated: 15 Jul 2024