Protein: RPOM
DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)

Gene: RPOM, POLRMT
Organism: Homo sapiens
Interactions: 207
UniProt ID: O00411

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0001018 - mitochondrial promoter sequence-specific DNA binding
GO:0003723 - RNA binding
GO:0003896 - DNA primase activity
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

127577

TFB2M
Dimethyladenosine transferase 2, mitochondrial

2

1

Small-scale

0.754

High

127539

TFB1M
Dimethyladenosine transferase 1, mitochondrial

1

3

Small-scale

0.724

High

127451

IKBA
NF-kappa-B inhibitor alpha

5

1

Small-scale

0.652

High

127476

RM12
Large ribosomal subunit protein bL12m

3

0

Small-scale

0.646

High

127533

KCD17
BTB/POZ domain-containing protein KCTD17

3

2

High-throughput

0.609

High

127525

DHX32
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32

2

0

High-throughput

0.602

High

127502

ICT1
Large ribosomal subunit protein mL62

2

0

High-throughput

0.585

High

127557

TEFM
Transcription elongation factor, mitochondrial

2

0

Small-scale

0.585

High

127544

NELL1
Protein kinase C-binding protein NELL1

2

3

High-throughput

0.574

High

127550

VWCE
von Willebrand factor C and EGF domain-containing protein

2

4

High-throughput

0.574

High

127560

NELL2
Protein kinase C-binding protein NELL2

2

3

High-throughput

0.574

High

127432

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

127495

GRB10
Growth factor receptor-bound protein 10

2

1

High-throughput

0.571

High

127418

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

127491

GRSF1
G-rich sequence factor 1

2

0

High-throughput

0.559

High

127508

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

127483

TFAM
Transcription factor A, mitochondrial

2

0

Small-scale

0.547

High

127420

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

1

High-throughput

0.536

High

127422

ERAL1
GTPase Era, mitochondrial

1

1

High-throughput

0.536

High

127468

KSYK
Tyrosine-protein kinase SYK

1

1

High-throughput

0.536

High

127480

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.536

High

127612

RT02
Small ribosomal subunit protein uS2m

1

1

High-throughput

0.536

High

127442

FGFR1
Fibroblast growth factor receptor 1

2

1

High-throughput

0.521

High

127466

KPCI
Protein kinase C iota type

2

1

High-throughput

0.521

High

127488

KPCZ
Protein kinase C zeta type

2

1

High-throughput

0.521

High

127412

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

0

High-throughput

0.513

High

127423

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.513

High

127434

P53
Cellular tumor antigen p53

1

0

High-throughput

0.513

High

127436

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

127444

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.513

High

127453

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.513

High

127454

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.513

High

127455

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

127457

GRN
Progranulin

1

0

High-throughput

0.513

High

127463

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.513

High

127473

CTCF
Transcriptional repressor CTCF

1

0

High-throughput

0.513

High

127475

HDGF
Hepatoma-derived growth factor

1

0

High-throughput

0.513

High

127481

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.513

High

127506

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.513

High

127520

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

0

High-throughput

0.513

High

127530

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

127553

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.513

High

127580

PAAT
ATPase PAAT

1

0

High-throughput

0.513

High

127586

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.513

High

127601

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.513

High

127602

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.513

High

127611

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

127614

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.513

High

127460

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.489

High

127535

KCTD6
BTB/POZ domain-containing protein KCTD6

1

1

High-throughput

0.489

High

127555

HIPL1
HHIP-like protein 1

1

1

High-throughput

0.489

High

127596

FBLN5
Fibulin-5

1

1

High-throughput

0.489

High

127607

SRPK3
SRSF protein kinase 3

1

2

High-throughput

0.489

High

127440

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

127419

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

127421

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

127429

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

127433

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

127470

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

127490

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

127516

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

127518

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

1

Small-scale

0.479

High

127526

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

3

High-throughput

0.479

High

127542

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

127546

FAKD4
FAST kinase domain-containing protein 4

1

3

High-throughput

0.479

High

127573

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

127581

RC3H2
Roquin-2

1

1

High-throughput

0.479

High

127590

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

3

High-throughput

0.479

High

127599

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

63237

MET15
12S rRNA N4-methylcytidine

1

0

High-throughput

0.458

High

122352

MEN1
Menin

1

0

High-throughput

0.458

High

127413

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

127416

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

127425

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

127430

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

127431

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

127437

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

127438

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

127439

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

127441

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

127443

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

127447

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

127450

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.458

High

127465

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

127467

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

127469

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

127472

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

127479

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

127487

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

127489

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

127492

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

127493

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.458

High

127494

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

127496

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

127497

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

127498

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

127500

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

127507

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.458

High

127509

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

127511

OXLD1
Oxidoreductase-like domain-containing protein 1

1

0

High-throughput

0.458

High

127512

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

127523

DHX30
ATP-dependent RNA helicase DHX30

1

0

High-throughput

0.458

High

127524

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

127529

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.458

High

127532

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

127538

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

127541

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

127545

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

127547

MCUR1
Mitochondrial calcium uniporter regulator 1

1

0

High-throughput

0.458

High

127549

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

0

High-throughput

0.458

High

127551

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

127552

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

127558

EFGM
Elongation factor G, mitochondrial

1

0

High-throughput

0.458

High

127563

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

0

High-throughput

0.458

High

127564

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

127565

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.458

High

127566

TR61B
tRNA

1

0

High-throughput

0.458

High

127568

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

127570

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.458

High

127571

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

127572

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

127575

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

127578

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

127579

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

127582

ZFYV1
Zinc finger FYVE domain-containing protein 1

1

0

Small-scale

0.458

High

127587

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.458

High

127588

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

127592

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

127593

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

127613

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

127616

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.458

High

127504

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

3

Small-scale

0.445

High

127427

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.437

High

127477

RHOA
Transforming protein RhoA

1

1

High-throughput

0.437

High

127478

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

127482

RHOG
Rho-related GTP-binding protein RhoG

1

1

High-throughput

0.437

High

127484

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

1

High-throughput

0.437

High

127531

SKAP1
Src kinase-associated phosphoprotein 1

1

1

High-throughput

0.437

High

127534

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.437

High

127574

RHOJ
Rho-related GTP-binding protein RhoJ

1

2

High-throughput

0.437

High

127584

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.437

High

127605

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

127435

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

127513

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

127589

ATD3A
ATPase family AAA domain-containing protein 3A

1

0

High-throughput

0.426

High

127591

GRHL1
Grainyhead-like protein 1 homolog

1

0

High-throughput

0.426

High

127464

TNR3
Tumor necrosis factor receptor superfamily member 3

3

0

High-throughput

0.347

High

127597

TRI10
Tripartite motif-containing protein 10

3

0

High-throughput

0.347

High

127608

CLC11
C-type lectin domain family 11 member A

3

0

High-throughput

0.347

High

127417

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

2

0

High-throughput

0.328

High

127598

CCG5
Voltage-dependent calcium channel gamma-5 subunit

2

0

High-throughput

0.328

High

127499

CUL3
Cullin-3

2

0

High-throughput

0.318

High

127583

ANLN
Anillin

2

0

High-throughput

0.305

High

127600

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.305

High

127415

PDPK1
3-phosphoinositide-dependent protein kinase 1

2

0

High-throughput

0.298

High

127448

RAB5A
Ras-related protein Rab-5A

2

0

High-throughput

0.298

High

127414

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.279

Low

127449

KCNA4
Potassium voltage-gated channel subfamily A member 4

1

0

High-throughput

0.279

Low

127452

PTX3
Pentraxin-related protein PTX3

1

0

High-throughput

0.279

Low

127458

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

127471

NEST
Nestin

1

0

High-throughput

0.279

Low

127485

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

0

High-throughput

0.279

Low

127486

NOTC2
Neurogenic locus notch homolog protein 2

1

0

High-throughput

0.279

Low

127501

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.279

Low

127503

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

127510

KLH22
Kelch-like protein 22

1

0

High-throughput

0.279

Low

127514

BEND3
BEN domain-containing protein 3

1

0

High-throughput

0.279

Low

127515

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

127517

FAXC
Failed axon connections homolog

1

0

High-throughput

0.279

Low

127521

ZN574
Zinc finger protein 574

1

0

High-throughput

0.279

Low

127528

ZN467
Zinc finger protein 467

1

0

High-throughput

0.279

Low

127540

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.279

Low

127556

ZN668
Zinc finger protein 668

1

0

High-throughput

0.279

Low

127561

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

0

High-throughput

0.279

Low

127562

FEZ1
Fasciculation and elongation protein zeta-1

1

0

High-throughput

0.279

Low

127567

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.279

Low

127569

FOXQ1
Forkhead box protein Q1

1

0

High-throughput

0.279

Low

127585

LATS2
Serine/threonine-protein kinase LATS2

1

0

High-throughput

0.279

Low

127595

RNF14
E3 ubiquitin-protein ligase RNF14

1

0

High-throughput

0.279

Low

127604

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.279

Low

127609

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

127610

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.279

Low

127459

ERP29
Endoplasmic reticulum resident protein 29

1

0

High-throughput

0.269

Low

127424

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.249

Low

127426

HEXI1
Protein HEXIM1

1

0

High-throughput

0.249

Low

127428

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.249

Low

127445

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

0

High-throughput

0.249

Low

127446

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

127456

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

127461

H2B1B
Histone H2B type 1-B

1

0

High-throughput

0.249

Low

127462

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

127474

EMD
Emerin

1

0

High-throughput

0.249

Low

127505

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

127519

ZN746
Zinc finger protein 746

1

0

High-throughput

0.249

Low

127522

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

127527

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

127536

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

127537

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

127543

KAT6A
Histone acetyltransferase KAT6A

1

0

High-throughput

0.249

Low

127548

PF21A
PHD finger protein 21A

1

0

High-throughput

0.249

Low

127554

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

127559

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.249

Low

127576

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

127594

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low

127603

RCOR1
REST corepressor 1

1

0

High-throughput

0.249

Low

127606

CC14A
Dual specificity protein phosphatase CDC14A

1

0

High-throughput

0.249

Low

127615

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024