Protein: DVL1
Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1)

Gene: DVL1
Organism: Homo sapiens
Interactions: 127
UniProt ID: O14640

Gene Ontology (top 5):
GO:0001933 - negative regulation of protein phosphorylation
GO:0001934 - positive regulation of protein phosphorylation
GO:0001947 - heart looping
GO:0003151 - outflow tract morphogenesis
GO:0005109 - frizzled binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

150648

DVL2
Segment polarity protein dishevelled homolog DVL-2

7

14

Small-scale

0.954

High

150739

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

15

Small-scale

0.828

High

150651

AXIN1
Axin-1

3

17

Small-scale

0.827

High

150742

FBXW7
F-box/WD repeat-containing protein 7

1

4

High-throughput

0.698

High

150647

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

14

Small-scale

0.690

High

150688

KC1E
Casein kinase I isoform epsilon

2

20

Small-scale

0.649

High

150694

DAB2
Disabled homolog 2

1

20

Small-scale

0.647

High

150735

DCAF4
DDB1- and CUL4-associated factor 4

2

0

High-throughput

0.631

High

150714

KLH12
Kelch-like protein 12

2

8

Small-scale

0.629

High

150746

SIPA1
Signal-induced proliferation-associated protein 1

1

14

High-throughput

0.621

High

150691

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

9

High-throughput

0.618

High

150717

A16L1
Autophagy-related protein 16-1

1

16

High-throughput

0.618

High

150728

ARHGJ
Rho guanine nucleotide exchange factor 19

1

16

Small-scale

0.618

High

150729

AHI1
Jouberin

1

13

High-throughput

0.618

High

150731

NUP43
Nucleoporin Nup43

1

4

High-throughput

0.618

High

150732

COP1
E3 ubiquitin-protein ligase COP1

1

3

High-throughput

0.618

High

150734

PARD3
Partitioning defective 3 homolog

1

19

High-throughput

0.618

High

150744

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

10

High-throughput

0.618

High

150765

FBW1A
F-box/WD repeat-containing protein 1A

1

5

High-throughput

0.618

High

150751

WWTR1
WW domain-containing transcription regulator protein 1

2

20

Small-scale

0.612

High

150661

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

8

High-throughput

0.584

High

150673

APC
Adenomatous polyposis coli protein

2

20

Small-scale

0.584

High

150718

RNF43
E3 ubiquitin-protein ligase RNF43

2

8

Small-scale

0.584

High

150757

WWOX
WW domain-containing oxidoreductase

2

3

High-throughput

0.584

High

150698

EPS8
Epidermal growth factor receptor kinase substrate 8

1

20

Small-scale

0.573

High

150715

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

Small-scale

0.573

High

150657

FZD7
Frizzled-7

1

20

Small-scale

0.561

High

150720

SCYL2
SCY1-like protein 2

1

9

Small-scale

0.561

High

150659

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

4

High-throughput

0.553

High

150696

TLE2
Transducin-like enhancer protein 2

1

13

High-throughput

0.553

High

150723

HECW1
E3 ubiquitin-protein ligase HECW1

1

20

Small-scale

0.552

High

150654

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

20

High-throughput

0.541

High

150666

RB
Retinoblastoma-associated protein

1

3

High-throughput

0.541

High

150738

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

5

High-throughput

0.541

High

63620

RASFA
Ras association domain-containing protein 10

1

8

High-throughput

0.536

High

150658

RASF9
Ras association domain-containing protein 9

1

12

High-throughput

0.536

High

150689

PLK1
Serine/threonine-protein kinase PLK1

1

15

High-throughput

0.536

High

150711

ZNF74
Zinc finger protein 74

1

6

High-throughput

0.536

High

150756

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

1

High-throughput

0.536

High

150745

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

7

Small-scale

0.534

High

150719

NXN
Nucleoredoxin

1

5

High-throughput

0.515

High

150740

NKD2
Protein naked cuticle homolog 2

1

10

Small-scale

0.515

High

150650

SMAD7
Mothers against decapentaplegic homolog 7

1

18

Small-scale

0.501

High

150684

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

20

Small-scale

0.501

High

150693

SMAD3
Mothers against decapentaplegic homolog 3

1

18

Small-scale

0.501

High

150701

SMAD4
Mothers against decapentaplegic homolog 4

1

20

Small-scale

0.501

High

150709

SMAD2
Mothers against decapentaplegic homolog 2

1

18

Small-scale

0.501

High

150710

SMAD1
Mothers against decapentaplegic homolog 1

1

18

Small-scale

0.501

High

150759

DAPLE
Protein Daple

1

20

Small-scale

0.501

High

150653

NCK2
Cytoplasmic protein NCK2

1

20

High-throughput

0.481

High

150662

BAG3
BAG family molecular chaperone regulator 3

1

3

High-throughput

0.481

High

150674

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.481

High

150726

TRI69
E3 ubiquitin-protein ligase TRIM69

1

3

High-throughput

0.481

High

116523

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

2

High-throughput

0.479

High

124995

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

20

Small-scale

0.479

High

150649

XPO1
Exportin-1

1

5

High-throughput

0.479

High

150655

KDM1A
Lysine-specific histone demethylase 1A

1

4

High-throughput

0.479

High

150656

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

13

High-throughput

0.479

High

150663

LATS1
Serine/threonine-protein kinase LATS1

1

20

High-throughput

0.479

High

150665

K2C8
Keratin, type II cytoskeletal 8

1

4

High-throughput

0.479

High

150668

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.479

High

150670

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.479

High

150671

CXA1
Gap junction alpha-1 protein

1

9

High-throughput

0.479

High

150677

CTNA1
Catenin alpha-1

1

9

High-throughput

0.479

High

150678

CTNB1
Catenin beta-1

1

19

Small-scale

0.479

High

150680

SYUA
Alpha-synuclein

1

7

High-throughput

0.479

High

150681

CETN2
Centrin-2

1

1

High-throughput

0.479

High

150683

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

13

High-throughput

0.479

High

150685

KC1D
Casein kinase I isoform delta

1

9

Small-scale

0.479

High

150686

PAXI
Paxillin

1

10

High-throughput

0.479

High

150687

ARRB1
Beta-arrestin-1

1

8

Small-scale

0.479

High

150692

CSK21
Casein kinase II subunit alpha

1

8

Small-scale

0.479

High

150695

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.479

High

150700

CTBP1
C-terminal-binding protein 1

1

6

High-throughput

0.479

High

150702

HDAC1
Histone deacetylase 1

1

8

High-throughput

0.479

High

150703

TFDP1
Transcription factor Dp-1

1

2

Small-scale

0.479

High

150704

DCTN1
Dynactin subunit 1

1

20

High-throughput

0.479

High

150705

FLNC
Filamin-C

1

20

High-throughput

0.479

High

150706

NUMA1
Nuclear mitotic apparatus protein 1

1

18

Small-scale

0.479

High

150707

KS6A2
Ribosomal protein S6 kinase alpha-2

1

8

High-throughput

0.479

High

150712

OCLN
Occludin

1

7

High-throughput

0.479

High

150713

MOONR
Protein moonraker

1

1

High-throughput

0.479

High

150716

CP135
Centrosomal protein of 135 kDa

1

20

High-throughput

0.479

High

150721

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

150725

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

20

Small-scale

0.479

High

150737

ARHG2
Rho guanine nucleotide exchange factor 2

1

20

Small-scale

0.479

High

150747

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

20

Small-scale

0.479

High

150752

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

20

Small-scale

0.479

High

150754

MLXPL
Carbohydrate-responsive element-binding protein

1

10

Small-scale

0.479

High

150755

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

4

Small-scale

0.479

High

150760

ANFY1
Rabankyrin-5

1

9

High-throughput

0.479

High

150762

RCOR1
REST corepressor 1

1

3

High-throughput

0.479

High

150763

ZNRF3
E3 ubiquitin-protein ligase ZNRF3

1

7

Small-scale

0.479

High

150764

MARE3
Microtubule-associated protein RP/EB family member 3

1

3

High-throughput

0.479

High

150767

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

2

High-throughput

0.479

High

150768

DAAM1
Disheveled-associated activator of morphogenesis 1

1

7

Small-scale

0.479

High

150769

CEP83
Centrosomal protein of 83 kDa

1

20

High-throughput

0.479

High

150672

ANXA7
Annexin A7

1

3

High-throughput

0.464

High

150652

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.458

High

150660

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.458

High

150724

DET1
DET1 homolog

1

0

High-throughput

0.458

High

150736

FRAT1
Proto-oncogene FRAT1

1

0

Small-scale

0.458

High

150667

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

10

Small-scale

0.457

High

150697

FAK1
Focal adhesion kinase 1

1

20

Small-scale

0.445

High

150690

ATN1
Atrophin-1

1

12

Small-scale

0.439

High

150730

SMYD1
Histone-lysine N-methyltransferase SMYD1

1

1

High-throughput

0.439

High

150664

TOP3B
DNA topoisomerase 3-beta-1

1

2

High-throughput

0.437

High

150669

IFM1
Interferon-induced transmembrane protein 1

1

4

High-throughput

0.437

High

150675

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

150679

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

150699

RFA4
Replication protein A 30 kDa subunit

1

10

High-throughput

0.437

High

150722

CE128
Centrosomal protein of 128 kDa

1

20

High-throughput

0.437

High

150727

TMM17
Transmembrane protein 17

1

3

High-throughput

0.437

High

150741

NKD1
Protein naked cuticle homolog 1

1

10

Small-scale

0.437

High

150743

PF21A
PHD finger protein 21A

1

8

High-throughput

0.437

High

150748

CEP19
Centrosomal protein of 19 kDa

1

3

High-throughput

0.437

High

150750

CEP44
Centrosomal protein of 44 kDa

1

2

High-throughput

0.437

High

150753

E41LA
Band 4.1-like protein 4A

1

20

High-throughput

0.437

High

150758

SEP10
Septin-10

1

12

High-throughput

0.437

High

150766

ADIP
Afadin- and alpha-actinin-binding protein

1

5

High-throughput

0.437

High

150682

MSH2
DNA mismatch repair protein Msh2

1

0

High-throughput

0.282

High

150761

MLH3
DNA mismatch repair protein Mlh3

1

0

High-throughput

0.282

High

150676

SDC4
Syndecan-4

1

0

Small-scale

0.249

Low

150708

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.249

Low

150733

TP4AP
Short transient receptor potential channel 4-associated protein

1

0

High-throughput

0.249

Low

150749

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024