Protein: DOCK7
Dedicator of cytokinesis protein 7

Gene: DOCK7
Organism: Homo sapiens
Interactions: 218
UniProt ID: Q96N67

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005925 - focal adhesion
GO:0007264 - small GTPase-mediated signal transduction
GO:0007409 - axonogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1244073

DOCK8
Dedicator of cytokinesis protein 8

7

11

High-throughput

0.965

High

1293664

DOCK6
Dedicator of cytokinesis protein 6

3

11

High-throughput

0.861

High

894322

CDC42
Cell division control protein 42 homolog

2

20

Small-scale

0.806

High

925526

RAC1
Ras-related C3 botulinum toxin substrate 1

2

20

Small-scale

0.806

High

1294469

LRCH3
DISP complex protein LRCH3

7

12

High-throughput

0.685

High

904999

1433G
14-3-3 protein gamma

3

20

High-throughput

0.675

High

1298545

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

6

12

High-throughput

0.672

High

169123

ARPC3
Actin-related protein 2/3 complex subunit 3

3

1

High-throughput

0.667

High

927415

1433Z
14-3-3 protein zeta/delta

3

20

High-throughput

0.667

High

1298542

MYO6
Unconventional myosin-VI

4

3

Small-scale

0.644

High

323018

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

3

1

High-throughput

0.640

High

1185495

MOB1B
MOB kinase activator 1B

4

11

High-throughput

0.638

High

982391

1433F
14-3-3 protein eta

4

20

High-throughput

0.638

High

909920

1433E
14-3-3 protein epsilon

2

5

High-throughput

0.635

High

1138582

LRCH2
Leucine-rich repeat and calponin homology domain-containing protein 2

4

12

High-throughput

0.633

High

264517

LRCH4
Leucine-rich repeat and calponin homology domain-containing protein 4

4

12

High-throughput

0.626

High

120587

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

350459

RASK
GTPase KRas

1

14

High-throughput

0.618

High

915899

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

1070346

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.618

High

1298523

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

683630

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.611

High

260668

AVIL
Advillin

2

0

High-throughput

0.602

High

228401

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

1298532

TMOD3
Tropomodulin-3

2

1

High-throughput

0.574

High

1191825

RHG30
Rho GTPase-activating protein 30

2

4

High-throughput

0.571

High

1298521

MOB1A
MOB kinase activator 1A

2

11

High-throughput

0.558

High

348871

RASN
GTPase NRas

1

13

High-throughput

0.553

High

117798

MYO1C
Unconventional myosin-Ic

1

2

High-throughput

0.536

High

307096

RTN3
Reticulon-3

1

2

High-throughput

0.536

High

323974

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

569003

CAN2
Calpain-2 catalytic subunit

1

4

High-throughput

0.536

High

724970

MYH9
Myosin-9

1

1

High-throughput

0.536

High

734996

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

4

High-throughput

0.536

High

1285050

ARRD3
Arrestin domain-containing protein 3

1

2

High-throughput

0.536

High

1298526

RTN4
Reticulon-4

1

2

High-throughput

0.536

High

818365

SOX2
Transcription factor SOX-2

2

1

High-throughput

0.533

High

383938

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

6

Small-scale

0.528

High

347621

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.521

High

519255

KCRB
Creatine kinase B-type

2

1

High-throughput

0.521

High

531953

PDIA4
Protein disulfide-isomerase A4

2

2

High-throughput

0.521

High

536422

GLU2B
Glucosidase 2 subunit beta

2

1

High-throughput

0.521

High

607137

UBA1
Ubiquitin-like modifier-activating enzyme 1

2

1

High-throughput

0.521

High

1267525

TSC1
Hamartin

1

5

Small-scale

0.515

High

535914

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.513

High

1296781

MARK4
MAP/microtubule affinity-regulating kinase 4

1

0

High-throughput

0.513

High

1054081

GRB7
Growth factor receptor-bound protein 7

1

13

High-throughput

0.508

High

1169425

NBEL2
Neurobeachin-like protein 2

1

2

High-throughput

0.506

High

529583

CFTR
Cystic fibrosis transmembrane conductance regulator

2

1

High-throughput

0.504

High

1282011

TRI63
E3 ubiquitin-protein ligase TRIM63

1

8

High-throughput

0.494

High

1298510

TRI55
Tripartite motif-containing protein 55

1

8

High-throughput

0.494

High

66695

ZN785
Zinc finger protein 785

1

2

High-throughput

0.489

High

207183

TGM5
Protein-glutamine gamma-glutamyltransferase 5

1

2

High-throughput

0.489

High

276268

CIB2
Calcium and integrin-binding family member 2

1

2

High-throughput

0.489

High

586930

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.489

High

639050

S100P
Protein S100-P

1

5

High-throughput

0.489

High

718116

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.489

High

801316

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.489

High

815015

LEG7
Galectin-7

1

1

High-throughput

0.489

High

862092

DAPK1
Death-associated protein kinase 1

1

3

High-throughput

0.489

High

902996

DCAF7
DDB1- and CUL4-associated factor 7

1

1

High-throughput

0.489

High

1151811

ISM2
Isthmin-2

1

1

High-throughput

0.489

High

1170339

CAN12
Calpain-12

1

3

High-throughput

0.489

High

1216621

CRLF3
Cytokine receptor-like factor 3

1

2

High-throughput

0.489

High

1284765

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.489

High

1293033

MYO19
Unconventional myosin-XIX

1

4

High-throughput

0.489

High

1297435

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

1298504

TCPQM
T-complex protein 1 subunit theta-like 2

1

5

High-throughput

0.489

High

1298505

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

1298517

TXNIP
Thioredoxin-interacting protein

1

2

High-throughput

0.489

High

1298522

PKHA1
Pleckstrin homology domain-containing family A member 1

1

3

High-throughput

0.489

High

1298525

CAN10
Calpain-10

1

2

High-throughput

0.489

High

1298544

AKT3
RAC-gamma serine/threonine-protein kinase

1

2

High-throughput

0.489

High

742476

SYUA
Alpha-synuclein

1

0

High-throughput

0.486

High

1084872

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

163160

XPO1
Exportin-1

1

3

High-throughput

0.479

High

374712

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.479

High

385362

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

430305

PROF1
Profilin-1

1

3

High-throughput

0.479

High

433950

LYN
Tyrosine-protein kinase Lyn

1

7

High-throughput

0.479

High

647195

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

793428

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.479

High

835497

GSK3A
Glycogen synthase kinase-3 alpha

1

5

High-throughput

0.479

High

835949

GSK3B
Glycogen synthase kinase-3 beta

1

5

High-throughput

0.479

High

969926

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

1021447

ANK3
Ankyrin-3

1

2

High-throughput

0.479

High

1044060

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

2

High-throughput

0.479

High

1169492

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

5

High-throughput

0.479

High

1298535

HDAC6
Histone deacetylase 6

1

3

High-throughput

0.479

High

1298538

FBW1B
F-box/WD repeat-containing protein 11

1

3

High-throughput

0.479

High

301433

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

3

High-throughput

0.470

High

1174284

MOB3C
MOB kinase activator 3C

1

11

High-throughput

0.470

High

1273802

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

1

High-throughput

0.470

High

589233

ANXA7
Annexin A7

1

4

High-throughput

0.464

High

915263

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

1

High-throughput

0.464

High

298729

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

547184

EZRI
Ezrin

1

0

High-throughput

0.458

High

842383

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

913050

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

932334

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

1298503

FMNL2
Formin-like protein 2

1

0

High-throughput

0.458

High

1298506

SIKE1
Suppressor of IKBKE 1

1

0

High-throughput

0.458

High

1298509

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.458

High

1298516

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

165011

SC16A
Protein transport protein Sec16A

1

1

High-throughput

0.457

High

240143

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.445

High

101085

APRIO
Alternative prion protein

1

1

Small-scale

0.439

High

1298529

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

129037

PLK4
Serine/threonine-protein kinase PLK4

1

3

High-throughput

0.437

High

160720

AURKA
Aurora kinase A

1

5

High-throughput

0.437

High

301976

TRI37
E3 ubiquitin-protein ligase TRIM37

1

7

High-throughput

0.437

High

409198

K2C8
Keratin, type II cytoskeletal 8

1

1

High-throughput

0.437

High

422082

LDHB
L-lactate dehydrogenase B chain

1

3

High-throughput

0.437

High

455767

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.437

High

601979

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

8

Small-scale

0.437

High

684270

1433S
14-3-3 protein sigma

1

20

High-throughput

0.437

High

777685

MDHM
Malate dehydrogenase, mitochondrial

1

3

High-throughput

0.437

High

779936

CCNF
Cyclin-F

1

2

High-throughput

0.437

High

870872

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.437

High

881550

ARL4C
ADP-ribosylation factor-like protein 4C

1

3

High-throughput

0.437

High

908976

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

1038634

HDAC1
Histone deacetylase 1

1

2

High-throughput

0.437

High

1042312

CUL3
Cullin-3

1

5

High-throughput

0.437

High

1043168

CUL4A
Cullin-4A

1

5

High-throughput

0.437

High

1064047

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.437

High

1066546

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.437

High

1119462

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

1

High-throughput

0.437

High

1166861

LRC31
Leucine-rich repeat-containing protein 31

1

4

High-throughput

0.437

High

1171295

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1188732

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1198334

MOB3B
MOB kinase activator 3B

1

11

High-throughput

0.437

High

1203502

SKAP1
Src kinase-associated phosphoprotein 1

1

11

High-throughput

0.437

High

1269394

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

1281320

FBXW7
F-box/WD repeat-containing protein 7

1

3

High-throughput

0.437

High

1283033

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1285327

PF21A
PHD finger protein 21A

1

1

High-throughput

0.437

High

1292170

AURKB
Aurora kinase B

1

5

High-throughput

0.437

High

1298507

DUS26
Dual specificity protein phosphatase 26

1

2

High-throughput

0.437

High

1298508

CP250
Centrosome-associated protein CEP250

1

1

High-throughput

0.437

High

1298515

WWTR1
WW domain-containing transcription regulator protein 1

1

2

High-throughput

0.437

High

1298528

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.437

High

1298531

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

1

High-throughput

0.437

High

1298534

PD1L1
Programmed cell death 1 ligand 1

1

3

Small-scale

0.437

High

1298536

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

1298537

DS13B
Dual specificity protein phosphatase 13B

1

2

High-throughput

0.437

High

1298539

RCOR1
REST corepressor 1

1

1

High-throughput

0.437

High

1298540

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.437

High

1298548

NEMO
NF-kappa-B essential modulator

1

5

Small-scale

0.437

High

395519

A4
Amyloid-beta precursor protein

1

0

Small-scale

0.426

High

1039150

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

0

High-throughput

0.426

High

1130461

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

484036

CALM2
Calmodulin-2

1

1

High-throughput

0.407

High

484184

CALM3
Calmodulin-3

1

1

High-throughput

0.407

High

787292

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

High-throughput

0.407

High

997442

VAC14
Protein VAC14 homolog

1

3

High-throughput

0.407

High

1160713

CSAG1
Chondrosarcoma-associated gene 1 protein

1

3

High-throughput

0.407

High

1298518

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

1

High-throughput

0.407

High

1298547

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

3

High-throughput

0.407

High

793144

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

0

High-throughput

0.347

High

1298530

PIHD1
PIH1 domain-containing protein 1

3

0

High-throughput

0.347

High

758313

CDN1A
Cyclin-dependent kinase inhibitor 1

2

0

High-throughput

0.313

High

1083351

RBBP7
Histone-binding protein RBBP7

2

0

High-throughput

0.298

High

1298514

API5
Apoptosis inhibitor 5

2

0

High-throughput

0.298

High

63666

RASFA
Ras association domain-containing protein 10

1

0

High-throughput

0.279

Low

204027

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.279

Low

225898

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

1

0

High-throughput

0.279

Low

260597

TP4A3
Protein tyrosine phosphatase type IVA 3

1

0

High-throughput

0.279

Low

277343

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.279

Low

330400

CX001
Putative transmembrane protein CXorf1

1

0

High-throughput

0.279

Low

538590

CCNB1
G2/mitotic-specific cyclin-B1

1

0

High-throughput

0.279

Low

625564

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.279

Low

813133

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.279

Low

813684

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

921396

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.279

Low

986834

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.279

Low

996120

HDHD1
Pseudouridine-5'-phosphatase

1

0

High-throughput

0.279

Low

1022755

MALL
MAL-like protein

1

0

High-throughput

0.279

Low

1056453

IRF3
Interferon regulatory factor 3

1

0

High-throughput

0.279

Low

1128354

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.279

Low

1232953

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1243473

KLDC9
Kelch domain-containing protein 9

1

0

High-throughput

0.279

Low

1288807

ERLEC
Endoplasmic reticulum lectin 1

1

0

High-throughput

0.279

Low

1298512

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.279

Low

1298513

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.279

Low

1298519

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.279

Low

1298520

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.279

Low

1298541

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.279

Low

1298546

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.279

Low

1298524

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

0

Small-scale

0.275

Low

303808

RPP14
Ribonuclease P protein subunit p14

1

0

High-throughput

0.265

Low

378759

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.265

Low

992115

B2CL1
Bcl-2-like protein 1

1

0

High-throughput

0.265

Low

1298511

NSD3
Histone-lysine N-methyltransferase NSD3

1

0

High-throughput

0.265

Low

232434

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.249

Low

233590

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

273948

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.249

Low

387322

P53
Cellular tumor antigen p53

1

0

High-throughput

0.249

Low

553470

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

776375

MLH1
DNA mismatch repair protein Mlh1

1

0

High-throughput

0.249

Low

829051

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.249

Low

855418

TF2AA
Transcription initiation factor IIA subunit 1

1

0

High-throughput

0.249

Low

875239

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.249

Low

941326

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

959609

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

998987

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.249

Low

1085885

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.249

Low

1157440

PPR18
Phostensin

1

0

High-throughput

0.249

Low

1167533

SOSD1
Sclerostin domain-containing protein 1

1

0

Small-scale

0.249

Low

1244036

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

0

High-throughput

0.249

Low

1245135

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.249

Low

1260871

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

1267092

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.249

Low

1287558

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.249

Low

1298527

ANLN
Anillin

1

0

High-throughput

0.249

Low

1298533

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.249

Low

1298543

MTMR7
Myotubularin-related protein 7

1

0

High-throughput

0.249

Low

1032562

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.232

Low

1272545

CSN5
COP9 signalosome complex subunit 5

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024