Protein: SVIL
Supervillin (Archvillin) (p205/p250)

Gene: SVIL
Organism: Homo sapiens
Interactions: 223
UniProt ID: O95425

Gene Ontology (top 5):
GO:0002102 - podosome
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

313786

ACTB
Actin, cytoplasmic 1

2

20

Small-scale

0.754

High

313893

TMOD3
Tropomodulin-3

2

11

High-throughput

0.726

High

313776

CAZA2
F-actin-capping protein subunit alpha-2

4

3

High-throughput

0.699

High

313788

ARP2
Actin-related protein 2

1

19

High-throughput

0.691

High

313886

ANLN
Anillin

3

2

High-throughput

0.656

High

261060

SH3L1
Adapter SH3BGRL

3

2

High-throughput

0.650

High

313740

CFTR
Cystic fibrosis transmembrane conductance regulator

3

2

High-throughput

0.643

High

313777

CAPZB
F-actin-capping protein subunit beta

2

2

High-throughput

0.628

High

313783

DAPK1
Death-associated protein kinase 1

2

9

High-throughput

0.628

High

313758

TMOD1
Tropomodulin-1

1

11

High-throughput

0.618

High

313767

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

2

5

High-throughput

0.611

High

313719

ESR1
Estrogen receptor

2

12

Small-scale

0.586

High

313751

FLNA
Filamin-A

2

6

Small-scale

0.586

High

313827

KIF14
Kinesin-like protein KIF14

2

7

Small-scale

0.586

High

313903

LIMA1
LIM domain and actin-binding protein 1

2

3

Small-scale

0.586

High

313743

EZRI
Ezrin

2

1

High-throughput

0.584

High

313821

DX39B
Spliceosome RNA helicase DDX39B

2

2

Small-scale

0.584

High

313852

NIN
Ninein

2

12

High-throughput

0.584

High

313828

KPCD1
Serine/threonine-protein kinase D1

2

4

High-throughput

0.571

High

313864

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

3

Small-scale

0.561

High

270548

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

6

High-throughput

0.536

High

301465

WDR47
WD repeat-containing protein 47

1

3

High-throughput

0.536

High

313714

CHK2
Serine/threonine-protein kinase Chk2

1

4

High-throughput

0.536

High

313732

FBSP1
F-box/SPRY domain-containing protein 1

1

6

High-throughput

0.536

High

313754

CDK2
Cyclin-dependent kinase 2

1

2

High-throughput

0.536

High

313764

MYH9
Myosin-9

1

5

High-throughput

0.536

High

313766

MYH11
Myosin-11

1

5

High-throughput

0.536

High

313778

NEST
Nestin

1

8

High-throughput

0.536

High

313782

CAZA1
F-actin-capping protein subunit alpha-1

1

3

High-throughput

0.536

High

313787

DEST
Destrin

1

1

High-throughput

0.536

High

313789

DCAF7
DDB1- and CUL4-associated factor 7

1

3

High-throughput

0.536

High

313806

CENPE
Centromere-associated protein E

1

2

High-throughput

0.536

High

313812

CALD1
Caldesmon

1

18

High-throughput

0.536

High

313832

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

2

High-throughput

0.536

High

313835

DREB
Drebrin

1

3

High-throughput

0.536

High

313844

L2GL2
LLGL scribble cell polarity complex component 2

1

2

High-throughput

0.536

High

313845

KLC3
Kinesin light chain 3

1

1

High-throughput

0.536

High

313848

PAXI1
PAX-interacting protein 1

1

3

High-throughput

0.536

High

313850

ABRA
Actin-binding Rho-activating protein

1

2

High-throughput

0.536

High

313853

DYLT5
Dynein light chain Tctex-type 5

1

1

High-throughput

0.536

High

313855

ARRD4
Arrestin domain-containing protein 4

1

7

High-throughput

0.536

High

313857

TBCK
TBC domain-containing protein kinase-like protein

1

6

High-throughput

0.536

High

313858

HASP
Serine/threonine-protein kinase haspin

1

1

High-throughput

0.536

High

313863

MY18A
Unconventional myosin-XVIIIa

1

12

High-throughput

0.536

High

313868

MYO19
Unconventional myosin-XIX

1

9

High-throughput

0.536

High

313873

DNJC7
DnaJ homolog subfamily C member 7

1

2

High-throughput

0.536

High

313878

HDAC8
Histone deacetylase 8

1

3

High-throughput

0.536

High

313887

MYO5C
Unconventional myosin-Vc

1

5

High-throughput

0.536

High

313889

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.536

High

313906

MYH13
Myosin-13

1

5

High-throughput

0.536

High

313734

ANDR
Androgen receptor

1

10

Small-scale

0.527

High

313724

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.515

High

313725

HMGN2
Non-histone chromosomal protein HMG-17

1

1

High-throughput

0.515

High

313745

H15
Histone H1.5

1

1

High-throughput

0.515

High

313785

H2B1D
Histone H2B type 1-D

1

2

High-throughput

0.515

High

313838

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.515

High

313849

H2A2B
Histone H2A type 2-B

1

1

High-throughput

0.515

High

313865

H2B1H
Histone H2B type 1-H

1

2

High-throughput

0.515

High

313899

SPAST
Spastin

1

3

High-throughput

0.515

High

63916

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

0

High-throughput

0.513

High

260508

TP4A3
Protein tyrosine phosphatase type IVA 3

1

0

High-throughput

0.513

High

313729

CD14
Monocyte differentiation antigen CD14

1

0

High-throughput

0.513

High

313765

ADDA
Alpha-adducin

1

0

High-throughput

0.513

High

313814

MALL
MAL-like protein

1

0

High-throughput

0.513

High

313831

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

313859

JPH3
Junctophilin-3

1

0

High-throughput

0.513

High

313891

MTMRA
Myotubularin-related protein 10

1

0

High-throughput

0.513

High

313908

TPX2
Targeting protein for Xklp2

1

0

High-throughput

0.513

High

313750

NEBU
Nebulin

1

5

Small-scale

0.506

High

313801

DYLT1
Dynein light chain Tctex-type 1

1

1

Small-scale

0.501

High

313830

TRIP6
Thyroid receptor-interacting protein 6

1

4

Small-scale

0.501

High

313723

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.493

High

313796

H4
Histone H4

1

0

High-throughput

0.493

High

313808

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.493

High

313837

H31T
Histone H3.1t

1

0

High-throughput

0.493

High

313895

CFA97
Cilia- and flagella-associated protein 97

1

1

High-throughput

0.489

High

118149

HAX1
HCLS1-associated protein X-1

1

1

Small-scale

0.481

High

210970

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

3

Small-scale

0.481

High

259541

HMMR
Hyaluronan mediated motility receptor

1

14

Small-scale

0.481

High

313718

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

Small-scale

0.481

High

313722

GCR
Glucocorticoid receptor

1

11

Small-scale

0.481

High

313726

K1C18
Keratin, type I cytoskeletal 18

1

2

Small-scale

0.481

High

313727

HS90A
Heat shock protein HSP 90-alpha

1

2

Small-scale

0.481

High

313768

PPARG
Peroxisome proliferator-activated receptor gamma

1

11

Small-scale

0.481

High

313779

CENPF
Centromere protein F

1

15

Small-scale

0.481

High

313809

KMT2A
Histone-lysine N-methyltransferase 2A

1

1

Small-scale

0.481

High

313820

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

1

1

Small-scale

0.481

High

313823

KIF22
Kinesin-like protein KIF22

1

2

Small-scale

0.481

High

313840

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

5

Small-scale

0.481

High

313841

ODFP2
Outer dense fiber protein 2

1

9

Small-scale

0.481

High

313842

SPD2A
SH3 and PX domain-containing protein 2A

1

1

Small-scale

0.481

High

313896

STAR9
StAR-related lipid transfer protein 9

1

5

Small-scale

0.481

High

69507

MYO1G
Unconventional myosin-Ig [Cleaved into: Minor histocompatibility antigen HA-2

1

9

Small-scale

0.479

High

117540

MYO1C
Unconventional myosin-Ic

1

9

High-throughput

0.479

High

148246

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

204874

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

211447

ACTN4
Alpha-actinin-4

1

3

Small-scale

0.479

High

233125

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

279380

FLOT1
Flotillin-1

1

3

Small-scale

0.479

High

301506

TRI37
E3 ubiquitin-protein ligase TRIM37

1

5

High-throughput

0.479

High

308282

KI20A
Kinesin-like protein KIF20A

1

9

High-throughput

0.479

High

313711

LATS1
Serine/threonine-protein kinase LATS1

1

2

High-throughput

0.479

High

313715

FOS
Protein c-Fos

1

5

High-throughput

0.479

High

313716

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

313717

TNFA
Tumor necrosis factor

1

1

High-throughput

0.479

High

313720

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.479

High

313728

LYN
Tyrosine-protein kinase Lyn

1

4

Small-scale

0.479

High

313731

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

313735

H14
Histone H1.4

1

1

High-throughput

0.479

High

313736

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.479

High

313738

ACTN1
Alpha-actinin-1

1

3

Small-scale

0.479

High

313739

CADH1
Cadherin-1

1

1

High-throughput

0.479

High

313744

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

313748

ML12A
Myosin regulatory light chain 12A

1

2

Small-scale

0.479

High

313749

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

313753

GCSP
Glycine dehydrogenase

1

1

High-throughput

0.479

High

313756

1433T
14-3-3 protein theta

1

10

High-throughput

0.479

High

313757

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

313759

1433B
14-3-3 protein beta/alpha

1

10

High-throughput

0.479

High

313760

1433S
14-3-3 protein sigma

1

10

High-throughput

0.479

High

313761

CTNB1
Catenin beta-1

1

1

High-throughput

0.479

High

313763

RADI
Radixin

1

1

High-throughput

0.479

High

313771

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

313775

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

3

High-throughput

0.479

High

313780

VASP
Vasodilator-stimulated phosphoprotein

1

1

High-throughput

0.479

High

313784

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

313790

1433G
14-3-3 protein gamma

1

10

High-throughput

0.479

High

313791

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

5

High-throughput

0.479

High

313792

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

313793

1433E
14-3-3 protein epsilon

1

3

High-throughput

0.479

High

313797

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

2

Small-scale

0.479

High

313800

1433Z
14-3-3 protein zeta/delta

1

10

High-throughput

0.479

High

313803

VIGLN
Vigilin

1

2

High-throughput

0.479

High

313805

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

4

Small-scale

0.479

High

313807

KIF23
Kinesin-like protein KIF23

1

6

High-throughput

0.479

High

313811

1433F
14-3-3 protein eta

1

10

High-throughput

0.479

High

313819

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

5

Small-scale

0.479

High

313822

FLOT2
Flotillin-2

1

3

Small-scale

0.479

High

313826

TNIP1
TNFAIP3-interacting protein 1

1

12

High-throughput

0.479

High

313833

ZYX
Zyxin

1

3

High-throughput

0.479

High

313836

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

313839

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

3

High-throughput

0.479

High

313846

RICTR
Rapamycin-insensitive companion of mTOR

1

2

High-throughput

0.479

High

313847

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

11

High-throughput

0.479

High

313851

SYNPO
Synaptopodin

1

3

High-throughput

0.479

High

313856

BICD2
Protein bicaudal D homolog 2

1

13

High-throughput

0.479

High

313861

SSH1
Protein phosphatase Slingshot homolog 1

1

3

High-throughput

0.479

High

313862

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

313866

CHM4C
Charged multivesicular body protein 4c

1

4

High-throughput

0.479

High

313870

ASB16
Ankyrin repeat and SOCS box protein 16

1

6

High-throughput

0.479

High

313874

MEP50
Methylosome protein WDR77

1

3

High-throughput

0.479

High

313875

OVOL2
Transcription factor Ovo-like 2

1

6

Small-scale

0.479

High

313877

FACD2
Fanconi anemia group D2 protein

1

4

High-throughput

0.479

High

313880

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

313881

CHM4B
Charged multivesicular body protein 4b

1

4

High-throughput

0.479

High

313883

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.479

High

313885

ECT2
Protein ECT2

1

8

High-throughput

0.479

High

313888

PDLI7
PDZ and LIM domain protein 7

1

4

High-throughput

0.479

High

313898

HDAC6
Histone deacetylase 6

1

4

High-throughput

0.479

High

313900

ZO2
Tight junction protein ZO-2

1

1

High-throughput

0.479

High

313902

TES
Testin

1

3

High-throughput

0.479

High

313904

HOOK1
Protein Hook homolog 1

1

14

High-throughput

0.479

High

313905

MYH2
Myosin-2

1

5

Small-scale

0.479

High

313909

NINL
Ninein-like protein

1

7

High-throughput

0.479

High

69225

MI4GD
MIF4G domain-containing protein

1

0

Small-scale

0.460

High

313752

NDKB
Nucleoside diphosphate kinase B

1

0

Small-scale

0.460

High

313774

ATRX
Transcriptional regulator ATRX

1

0

Small-scale

0.460

High

313816

CENPR
Centromere protein R

1

0

Small-scale

0.460

High

313897

UXT
Protein UXT

1

0

Small-scale

0.460

High

313907

MRTFB
Myocardin-related transcription factor B

1

0

Small-scale

0.460

High

168098

TBX3
T-box transcription factor TBX3

1

0

High-throughput

0.458

High

313712

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

313730

VIME
Vimentin

1

0

Small-scale

0.458

High

313741

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.458

High

313742

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

0

High-throughput

0.458

High

313747

VGFR1
Vascular endothelial growth factor receptor 1

1

0

High-throughput

0.458

High

313755

STOM
Stomatin

1

0

Small-scale

0.458

High

313769

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

313770

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.458

High

313781

R144A
E3 ubiquitin-protein ligase RNF144A

1

0

Small-scale

0.458

High

313794

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

313795

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.458

High

313799

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

0

Small-scale

0.458

High

313804

CLH1
Clathrin heavy chain 1

1

0

Small-scale

0.458

High

313813

B2CL1
Bcl-2-like protein 1

1

0

High-throughput

0.458

High

313818

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

Small-scale

0.458

High

313843

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.458

High

313854

DTX3
Probable E3 ubiquitin-protein ligase DTX3

1

0

Small-scale

0.458

High

313860

ASB15
Ankyrin repeat and SOCS box protein 15

1

0

High-throughput

0.458

High

313890

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

313894

LUZP4
Leucine zipper protein 4

1

0

Small-scale

0.458

High

313901

ABCF2
ATP-binding cassette sub-family F member 2

1

0

High-throughput

0.458

High

313911

GPSM3
G-protein-signaling modulator 3

1

0

Small-scale

0.458

High

313737

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.457

High

313824

MYPC3
Myosin-binding protein C, cardiac-type

1

2

Small-scale

0.457

High

239672

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.445

High

313762

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.445

High

313772

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

2

High-throughput

0.445

High

313798

GRB2
Growth factor receptor-bound protein 2

1

8

High-throughput

0.445

High

313817

CTBP1
C-terminal-binding protein 1

1

3

High-throughput

0.445

High

313834

NF2L2
Nuclear factor erythroid 2-related factor 2

1

3

High-throughput

0.445

High

313872

ZBT18
Zinc finger and BTB domain-containing protein 18

1

6

High-throughput

0.445

High

313810

LMNB2
Lamin-B2

1

2

Small-scale

0.439

High

313884

PCX3
Pecanex-like protein 3

1

1

Small-scale

0.439

High

313746

ZNF16
Zinc finger protein 16

1

0

Small-scale

0.438

High

313773

KI2L1
Killer cell immunoglobulin-like receptor 2DL1

1

0

Small-scale

0.438

High

100344

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

313829

SYCP1
Synaptonemal complex protein 1

1

12

High-throughput

0.437

High

313733

CALM3
Calmodulin-3

1

0

High-throughput

0.426

High

313879

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

313892

SPHK1
Sphingosine kinase 1

1

0

Small-scale

0.426

High

313910

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.282

High

296189

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

0

High-throughput

0.279

Low

313713

CX001
Putative transmembrane protein CXorf1

1

0

High-throughput

0.279

Low

313802

CXCL6
C-X-C motif chemokine 6

1

0

High-throughput

0.279

Low

313815

GAGE5
G antigen 5

1

0

High-throughput

0.279

Low

313867

ERLEC
Endoplasmic reticulum lectin 1

1

0

High-throughput

0.279

Low

313825

T132D
Transmembrane protein 132D

1

0

Small-scale

0.251

Low

313871

MPP9
M-phase phosphoprotein 9

1

0

Small-scale

0.251

Low

313876

KIFC3
Kinesin-like protein KIFC3

1

0

Small-scale

0.251

Low

313721

GBA1
Lysosomal acid glucosylceramidase

1

0

Small-scale

0.249

Low

313869

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

313882

GAPR1
Golgi-associated plant pathogenesis-related protein 1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024