Protein: URA7
CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1)

Gene: URA7
Organism: Saccharomyces cerevisiae S288C
Interactions: 161
UniProt ID: P28274

Gene Ontology (top 5):
GO:0000324 - fungal-type vacuole
GO:0003883 - CTP synthase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006241 - CTP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

701696

URA8
CTP synthase 2

2

9

High-throughput

0.785

High

701665

URA7
CTP synthase 1

2

9

High-throughput

0.770

High

399349

CARB
Carbamoyl phosphate synthase arginine-specific large chain

2

1

High-throughput

0.759

High

518228

IF4A
ATP-dependent RNA helicase eIF4A

3

3

High-throughput

0.662

High

531263

METK1
S-adenosylmethionine synthase 1

3

1

High-throughput

0.662

High

701714

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

4

4

High-throughput

0.630

High

665786

KPC1
Protein kinase C-like 1

3

0

Small-scale

0.627

High

701681

PRS6B
26S proteasome regulatory subunit 6B homolog

2

2

High-throughput

0.621

High

701733

PRS8
26S proteasome regulatory subunit 8 homolog

2

3

High-throughput

0.621

High

701688

YKT6
Synaptobrevin homolog YKT6

3

0

High-throughput

0.616

High

701706

SSB2
Ribosome-associated molecular chaperone SSB2

3

6

High-throughput

0.611

High

701698

RPN1
26S proteasome regulatory subunit RPN1

2

1

High-throughput

0.611

High

701704

RV167
Reduced viability upon starvation protein 167

2

0

Small-scale

0.598

High

701738

CLU
Clustered mitochondria protein 1

2

0

High-throughput

0.595

High

701680

PRS6A
26S proteasome regulatory subunit 6A

2

1

High-throughput

0.588

High

392351

HSP82
ATP-dependent molecular chaperone HSP82

2

5

High-throughput

0.584

High

578972

HSC82
ATP-dependent molecular chaperone HSC82

2

5

High-throughput

0.584

High

453458

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.575

High

364960

KPYK1
Pyruvate kinase 1

2

1

High-throughput

0.571

High

434891

RS3
Small ribosomal subunit protein uS3

2

1

High-throughput

0.571

High

544050

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.571

High

701676

HSP7F
Heat shock protein homolog SSE1

2

9

High-throughput

0.571

High

470479

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

1

High-throughput

0.567

High

701699

RPN10
26S proteasome regulatory subunit RPN10

2

1

High-throughput

0.567

High

701743

RPN8
26S proteasome regulatory subunit RPN8

2

1

High-throughput

0.567

High

440826

KIN28
Serine/threonine-protein kinase KIN28

1

4

High-throughput

0.561

High

523256

HSP71
Heat shock protein SSA1

2

5

High-throughput

0.552

High

526092

HSP72
Heat shock protein SSA2

2

6

High-throughput

0.552

High

701737

GCN5
Histone acetyltransferase GCN5

2

1

High-throughput

0.549

High

701745

FDH1
Formate dehydrogenase 1

2

2

High-throughput

0.537

High

486067

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.536

High

688836

RS5
Small ribosomal subunit protein uS7

1

2

High-throughput

0.536

High

701731

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

512305

RS6A
Small ribosomal subunit protein eS6A

2

1

High-throughput

0.533

High

670414

SIS1
Protein SIS1

2

1

High-throughput

0.521

High

689310

RS7A
Small ribosomal subunit protein eS7A

2

1

High-throughput

0.521

High

701683

RS3A1
Small ribosomal subunit protein eS1A

2

1

High-throughput

0.521

High

701720

ASNS2
Asparagine synthetase [glutamine-hydrolyzing] 2

1

1

High-throughput

0.515

High

454418

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

701709

MAD2
Mitotic spindle checkpoint component MAD2

1

0

High-throughput

0.513

High

701711

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.513

High

701725

BUD32
EKC/KEOPS complex subunit BUD32

1

0

High-throughput

0.513

High

602347

PHO85
Cyclin-dependent protein kinase PHO85

1

3

High-throughput

0.501

High

666152

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

1

High-throughput

0.500

High

675276

DMC1
Meiotic recombination protein DMC1

1

1

High-throughput

0.500

High

701670

ARP2
Actin-related protein 2

1

3

High-throughput

0.500

High

701671

MKK2
MAP kinase kinase MKK2/SSP33

1

3

High-throughput

0.500

High

701693

IMB2
Importin subunit beta-2

1

1

High-throughput

0.500

High

701726

SSK2
MAP kinase kinase kinase SSK2

1

1

High-throughput

0.500

High

531635

RL4A
Large ribosomal subunit protein uL4A

1

2

High-throughput

0.489

High

701668

EF2
Elongation factor 2

1

3

High-throughput

0.489

High

701674

RPN2
26S proteasome regulatory subunit RPN2

1

1

High-throughput

0.489

High

701716

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.489

High

701734

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.489

High

517931

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.480

High

453911

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.479

High

633442

PP11
Serine/threonine-protein phosphatase PP1-1

1

0

High-throughput

0.479

High

644614

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.479

High

701705

HAT2
Histone acetyltransferase type B subunit 2

1

0

High-throughput

0.479

High

149632

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

364383

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.479

High

430796

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

3

Small-scale

0.479

High

435824

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

514502

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

587288

ABP1
Actin-binding protein

1

1

High-throughput

0.479

High

674463

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

679446

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

682187

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.479

High

701667

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

701673

ZUO1
Zuotin

1

1

Small-scale

0.479

High

701675

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.479

High

701677

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.479

High

701686

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

701690

LONM
Lon protease homolog, mitochondrial

1

4

High-throughput

0.479

High

701691

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

701697

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

701702

DHH1
ATP-dependent RNA helicase DHH1

1

4

High-throughput

0.479

High

701718

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

701727

HST2
NAD-dependent protein deacetylase HST2

1

1

High-throughput

0.479

High

701732

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

701741

SUB2
ATP-dependent RNA helicase SUB2

1

5

High-throughput

0.479

High

701749

KPR5
Ribose-phosphate pyrophosphokinase 5

1

1

High-throughput

0.479

High

701752

DBP10
ATP-dependent RNA helicase DBP10

1

4

High-throughput

0.479

High

558616

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

585686

UBC4
Ubiquitin-conjugating enzyme E2 4

1

0

High-throughput

0.458

High

597400

EF3A
Elongation factor 3A

1

0

High-throughput

0.458

High

646322

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

701669

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

701679

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

701695

SDS24
Protein SDS24

1

0

High-throughput

0.458

High

701736

ESP1
Separin

1

0

High-throughput

0.458

High

701742

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

701747

YP225
Protein PBDC1 homolog

1

0

High-throughput

0.458

High

701748

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

701753

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.458

High

701754

YOR31
Uncharacterized hydrolase YOR131C

1

0

High-throughput

0.458

High

701757

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.458

High

575308

EI2BA
Translation initiation factor eIF2B subunit alpha

1

1

High-throughput

0.457

High

701672

EI2BB
Translation initiation factor eIF2B subunit beta

1

1

High-throughput

0.457

High

701730

AP1M1
AP-1 complex subunit mu-1-I

1

1

High-throughput

0.457

High

701758

AP2M
AP-2 complex subunit mu

1

1

High-throughput

0.457

High

386604

TBB
Tubulin beta chain

1

1

High-throughput

0.445

High

394309

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

432513

RL7A
Large ribosomal subunit protein uL30A

1

2

High-throughput

0.445

High

592064

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.445

High

671585

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.445

High

675771

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

701682

PRS7
26S proteasome regulatory subunit 7 homolog

1

5

High-throughput

0.445

High

701721

RL4B
Large ribosomal subunit protein uL4B

1

2

High-throughput

0.445

High

701750

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

368142

THDH
Threonine dehydratase, mitochondrial

1

1

High-throughput

0.437

High

383566

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.437

High

409979

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.437

High

433498

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

454924

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

502896

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

504080

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

512868

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

513468

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.437

High

515058

RL19B
Large ribosomal subunit protein eL19

1

1

High-throughput

0.437

High

515224

RL35A
Large ribosomal subunit protein uL29A

1

1

High-throughput

0.437

High

548672

RNA1
Ran GTPase-activating protein 1

1

1

High-throughput

0.437

High

701666

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

701678

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

701708

RLP7
Ribosome biogenesis protein RLP7

1

2

High-throughput

0.437

High

701713

SET4
SET domain-containing protein 4

1

1

Small-scale

0.437

High

701719

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

701728

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

2

High-throughput

0.437

High

701744

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

701692

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.426

High

570220

RS17B
Small ribosomal subunit protein eS17B

1

2

High-throughput

0.407

High

689179

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.407

High

701684

SPT7
SAGA complex subunit SPT7

1

2

High-throughput

0.407

High

701715

RSSA2
Small ribosomal subunit protein uS2B

1

2

High-throughput

0.407

High

701735

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

1

High-throughput

0.407

High

701756

RL13A
Large ribosomal subunit protein eL13A

1

1

High-throughput

0.407

High

701707

LYS12
Homoisocitrate dehydrogenase, mitochondrial

3

0

High-throughput

0.335

High

701689

RM03
Large ribosomal subunit protein mL44

2

0

High-throughput

0.324

High

441753

RS14A
Small ribosomal subunit protein uS11A

2

0

High-throughput

0.318

High

660208

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.282

High

701710

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.282

High

701687

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.279

Low

701722

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.279

Low

701723

YGI1
Uncharacterized protein YGL081W

1

0

High-throughput

0.279

Low

701751

SWM1
Anaphase-promoting complex subunit SWM1

1

0

High-throughput

0.279

Low

701701

STT3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3

1

0

High-throughput

0.269

Low

459043

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.261

Low

701739

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.261

Low

513648

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

701685

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

701694

POA1
ADP-ribose 1''-phosphate phosphatase

1

0

High-throughput

0.249

Low

701703

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

701712

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

701724

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

701729

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.249

Low

701746

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

701717

GPI14
GPI mannosyltransferase 1

1

0

High-throughput

0.238

Low

701700

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.232

Low

701740

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.232

Low

701755

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025