Protein: SCN4A
Sodium channel protein type 4 subunit alpha (SkM1) (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4)

Gene: SCN4A
Organism: Homo sapiens
Interactions: 91
UniProt ID: P35499

Gene Ontology (top 5):
GO:0001518 - voltage-gated sodium channel complex
GO:0005248 - voltage-gated sodium channel activity
GO:0005886 - plasma membrane
GO:0006814 - sodium ion transport
GO:0006936 - muscle contraction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

723923

SCN8A
Sodium channel protein type 8 subunit alpha

1

5

High-throughput

0.691

High

723860

SCN1B
Sodium channel subunit beta-1

1

2

Small-scale

0.666

High

233055

FZD6
Frizzled-6

1

3

High-throughput

0.536

High

300335

AGRL1
Adhesion G protein-coupled receptor L1

1

7

High-throughput

0.536

High

313921

PIGN
GPI ethanolamine phosphate transferase 1

1

1

High-throughput

0.536

High

326036

TSN15
Tetraspanin-15

1

3

High-throughput

0.536

High

526491

GP1BB
Platelet glycoprotein Ib beta chain

1

4

High-throughput

0.536

High

566944

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.536

High

723854

AGRE5
Adhesion G protein-coupled receptor E5

1

10

High-throughput

0.536

High

723865

FZD2
Frizzled-2

1

3

High-throughput

0.536

High

723867

SLMAP
Sarcolemmal membrane-associated protein

1

9

High-throughput

0.536

High

723881

AGRG6
Adhesion G-protein coupled receptor G6

1

7

High-throughput

0.536

High

723887

MACOI
Macoilin

1

8

High-throughput

0.536

High

723901

DNJC1
DnaJ homolog subfamily C member 1

1

4

High-throughput

0.536

High

723906

SMO
Protein smoothened

1

3

High-throughput

0.536

High

723910

S1PR5
Sphingosine 1-phosphate receptor 5

1

4

High-throughput

0.536

High

723911

FZD8
Frizzled-8

1

3

High-throughput

0.536

High

723864

SNTA1
Alpha-1-syntrophin

1

11

Small-scale

0.527

High

306933

CSPG5
Chondroitin sulfate proteoglycan 5

1

0

High-throughput

0.513

High

723853

GLRB
Glycine receptor subunit beta

1

0

High-throughput

0.513

High

723866

ICAM4
Intercellular adhesion molecule 4

1

0

High-throughput

0.513

High

723871

CSCL2
CSC1-like protein 2

1

0

High-throughput

0.513

High

723873

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.513

High

723875

MFS12
Major facilitator superfamily domain-containing protein 12

1

0

High-throughput

0.513

High

723884

TM219
Insulin-like growth factor-binding protein 3 receptor

1

0

High-throughput

0.513

High

723889

S15A4
Solute carrier family 15 member 4

1

0

High-throughput

0.513

High

723891

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.513

High

723892

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.513

High

723894

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

723897

CTL1
Choline transporter-like protein 1

1

0

High-throughput

0.513

High

723905

S29A1
Equilibrative nucleoside transporter 1

1

0

High-throughput

0.513

High

723907

SELS
Selenoprotein S

1

0

High-throughput

0.513

High

723909

YIPF3
Protein YIPF3

1

0

High-throughput

0.513

High

723912

PIGU
Phosphatidylinositol glycan anchor biosynthesis class U protein

1

0

High-throughput

0.513

High

723918

CNNM1
Metal transporter CNNM1

1

0

High-throughput

0.513

High

723922

NB5R1
NADH-cytochrome b5 reductase 1

1

0

High-throughput

0.513

High

723903

ERBIN
Erbin

1

0

Small-scale

0.505

High

209318

TSN6
Tetraspanin-6

1

3

High-throughput

0.489

High

257747

SIN3B
Paired amphipathic helix protein Sin3b

1

1

High-throughput

0.489

High

573597

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

10

High-throughput

0.489

High

723877

XIRP1
Xin actin-binding repeat-containing protein 1

1

1

High-throughput

0.489

High

723878

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

1

High-throughput

0.489

High

723882

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

2

High-throughput

0.489

High

723883

CARM1
Histone-arginine methyltransferase CARM1

1

2

High-throughput

0.489

High

723895

PIGO
GPI ethanolamine phosphate transferase 3

1

1

High-throughput

0.489

High

723902

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

3

High-throughput

0.489

High

723924

DJC16
DnaJ homolog subfamily C member 16

1

4

High-throughput

0.489

High

558998

H15
Histone H1.5

1

1

High-throughput

0.470

High

723857

RL10A
Large ribosomal subunit protein uL1

1

2

High-throughput

0.470

High

723859

H11
Histone H1.1

1

1

High-throughput

0.470

High

723863

DNJC3
DnaJ homolog subfamily C member 3

1

1

High-throughput

0.470

High

474457

GPHRB
Golgi pH regulator B

1

1

High-throughput

0.437

High

81796

GPHRA
Golgi pH regulator A

1

1

High-throughput

0.407

High

723900

NEUL4
Neuralized-like protein 4

1

2

High-throughput

0.407

High

153887

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

5

Small-scale

0.373

High

63919

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

0

High-throughput

0.279

Low

200018

GPAA1
Glycosylphosphatidylinositol anchor attachment 1 protein

1

0

High-throughput

0.279

Low

238845

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

723852

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

723855

MFAP3
Microfibril-associated glycoprotein 3

1

0

High-throughput

0.279

Low

723856

SELT
Thioredoxin reductase-like selenoprotein T

1

0

High-throughput

0.279

Low

723858

EREP3
Protein ENTREP3

1

0

High-throughput

0.279

Low

723861

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

0

High-throughput

0.279

Low

723862

TMM62
Transmembrane protein 62

1

0

High-throughput

0.279

Low

723868

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

0

High-throughput

0.279

Low

723869

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.279

Low

723870

PPM1L
Protein phosphatase 1L

1

0

High-throughput

0.279

Low

723872

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.279

Low

723874

MYORG
Myogenesis-regulating glycosidase

1

0

High-throughput

0.279

Low

723876

TMPPE
Transmembrane protein with metallophosphoesterase domain

1

0

High-throughput

0.279

Low

723879

D19L4
Probable C-mannosyltransferase DPY19L4

1

0

High-throughput

0.279

Low

723880

PIGW
Phosphatidylinositol-glycan biosynthesis class W protein

1

0

High-throughput

0.279

Low

723885

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.279

Low

723886

GLT16
Polypeptide N-acetylgalactosaminyltransferase 16

1

0

High-throughput

0.279

Low

723888

PAR16
Protein mono-ADP-ribosyltransferase PARP16

1

0

High-throughput

0.279

Low

723890

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

0

High-throughput

0.279

Low

723893

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

High-throughput

0.279

Low

723896

NAT14
Probable N-acetyltransferase 14

1

0

High-throughput

0.279

Low

723898

F162A
Protein FAM162A

1

0

High-throughput

0.279

Low

723899

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

723904

SEC62
Translocation protein SEC62

1

0

High-throughput

0.279

Low

723908

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

1

0

High-throughput

0.279

Low

723913

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

723914

S38AA
Solute carrier family 38 member 10

1

0

High-throughput

0.279

Low

723915

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

0

High-throughput

0.279

Low

723916

CHSTB
Carbohydrate sulfotransferase 11

1

0

High-throughput

0.279

Low

723917

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.279

Low

723919

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

0

High-throughput

0.279

Low

723920

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.279

Low

723921

B4GT7
Beta-1,4-galactosyltransferase 7

1

0

High-throughput

0.279

Low

573149

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024