Protein: PASK
PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1)

Gene: PASK
Organism: Homo sapiens
Interactions: 157
UniProt ID: Q96RG2

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

160724

AURKA
Aurora kinase A

3

17

High-throughput

0.861

High

228426

PRKN
E3 ubiquitin-protein ligase parkin

3

16

High-throughput

0.855

High

1300860

PASK
PAS domain-containing serine/threonine-protein kinase

3

17

Small-scale

0.840

High

1188147

ZN550
Zinc finger protein 550

2

0

High-throughput

0.770

High

1169024

DEFI8
Differentially expressed in FDCP 8 homolog

2

14

High-throughput

0.726

High

1300861

RSLAB
Ras-like protein family member 10B

2

11

High-throughput

0.726

High

734998

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

17

High-throughput

0.691

High

848452

IRAK1
Interleukin-1 receptor-associated kinase 1

1

8

High-throughput

0.691

High

1073115

SF3B3
Splicing factor 3B subunit 3

1

1

High-throughput

0.691

High

1224566

CDK20
Cyclin-dependent kinase 20

1

7

High-throughput

0.691

High

1300863

NPAS1
Neuronal PAS domain-containing protein 1

1

3

High-throughput

0.691

High

1300880

NLK
Serine/threonine-protein kinase NLK

1

13

High-throughput

0.691

High

881891

WNT4
Protein Wnt-4

3

3

High-throughput

0.667

High

1224062

TRM2A
tRNA

3

1

High-throughput

0.667

High

1300888

KLK5
Kallikrein-5

3

3

High-throughput

0.667

High

274284

STK16
Serine/threonine-protein kinase 16

1

17

High-throughput

0.665

High

441557

MET
Hepatocyte growth factor receptor

1

12

Small-scale

0.647

High

724562

IRS1
Insulin receptor substrate 1

1

3

Small-scale

0.647

High

1025202

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

19

Small-scale

0.647

High

256002

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.618

High

432176

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

438448

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

779951

CCNF
Cyclin-F

1

9

High-throughput

0.618

High

801323

KI67
Proliferation marker protein Ki-67

1

4

High-throughput

0.618

High

803708

BAG6
Large proline-rich protein BAG6

1

8

High-throughput

0.618

High

835502

GSK3A
Glycogen synthase kinase-3 alpha

1

19

High-throughput

0.618

High

835955

GSK3B
Glycogen synthase kinase-3 beta

1

20

High-throughput

0.618

High

861898

PLK1
Serine/threonine-protein kinase PLK1

1

17

High-throughput

0.618

High

887205

DJB13
DnaJ homolog subfamily B member 13

1

12

High-throughput

0.618

High

1060599

ZN638
Zinc finger protein 638

1

2

High-throughput

0.618

High

1128073

CEP78
Centrosomal protein of 78 kDa

1

2

High-throughput

0.618

High

1300885

ZBT21
Zinc finger and BTB domain-containing protein 21

1

1

High-throughput

0.618

High

1300887

NINL
Ninein-like protein

1

11

High-throughput

0.618

High

902401

IPKA
cAMP-dependent protein kinase inhibitor alpha

1

0

Small-scale

0.614

High

1300876

EMIL3
EMILIN-3

2

8

High-throughput

0.611

High

1300883

AGO2
Protein argonaute-2

2

9

High-throughput

0.611

High

533048

PRG2
Bone marrow proteoglycan

3

1

High-throughput

0.609

High

1300868

IQCN
IQ domain-containing protein N

2

0

High-throughput

0.602

High

196655

ZBT24
Zinc finger and BTB domain-containing protein 24

1

0

High-throughput

0.586

High

1125497

ZN628
Zinc finger protein 628

1

0

High-throughput

0.586

High

1169080

ZN574
Zinc finger protein 574

1

0

High-throughput

0.586

High

1300870

ZN768
Zinc finger protein 768

1

0

High-throughput

0.586

High

1151041

SFRP4
Secreted frizzled-related protein 4

2

0

High-throughput

0.585

High

295153

RECQ4
ATP-dependent DNA helicase Q4

2

1

High-throughput

0.584

High

591984

RAB4A
Ras-related protein Rab-4A

1

8

Small-scale

0.579

High

1017026

KCNH2
Potassium voltage-gated channel subfamily H member 2

1

11

Small-scale

0.579

High

135870

WNT7A
Protein Wnt-7a

2

3

High-throughput

0.574

High

1190920

TAFA3
Chemokine-like protein TAFA-3

2

1

High-throughput

0.574

High

1237406

FRMD1
FERM domain-containing protein 1

2

11

High-throughput

0.574

High

556951

CREB1
Cyclic AMP-responsive element-binding protein 1

1

2

Small-scale

0.536

High

63939

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

1

High-throughput

0.536

High

439357

CATG
Cathepsin G

1

3

High-throughput

0.536

High

452002

WNT2
Protein Wnt-2

1

3

High-throughput

0.536

High

595561

GRAH
Granzyme H

1

3

High-throughput

0.536

High

795561

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

1

High-throughput

0.536

High

1021203

FOXD4
Forkhead box protein D4

1

2

High-throughput

0.536

High

1102056

ERC6L
DNA excision repair protein ERCC-6-like

1

1

High-throughput

0.536

High

1110371

FX4L6
Forkhead box protein D4-like 6

1

1

High-throughput

0.536

High

1191120

PODN
Podocan

1

2

High-throughput

0.536

High

1244197

NOXO1
NADPH oxidase organizer 1

1

8

High-throughput

0.536

High

1261076

TRI41
E3 ubiquitin-protein ligase TRIM41

1

2

High-throughput

0.536

High

1272803

FGF11
Fibroblast growth factor 11

1

2

High-throughput

0.536

High

1296582

WDR90
WD repeat-containing protein 90

1

4

High-throughput

0.536

High

1300864

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

9

High-throughput

0.536

High

1300878

KLH14
Kelch-like protein 14

1

3

High-throughput

0.536

High

594613

PSB1
Proteasome subunit beta type-1

1

3

High-throughput

0.515

High

603657

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.515

High

903449

WDR5
WD repeat-containing protein 5

1

6

High-throughput

0.515

High

916783

RS6
Small ribosomal subunit protein eS6

1

0

Small-scale

0.513

High

1274629

KPBB
Phosphorylase b kinase regulatory subunit beta

1

0

Small-scale

0.513

High

215675

AKAP8
A-kinase anchor protein 8

1

0

High-throughput

0.513

High

272378

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.513

High

540871

PO2F1
POU domain, class 2, transcription factor 1

1

0

High-throughput

0.513

High

726535

TIMP3
Metalloproteinase inhibitor 3

1

0

High-throughput

0.513

High

846704

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

1

0

High-throughput

0.513

High

942550

CTG1B
Cancer/testis antigen 1

1

0

High-throughput

0.513

High

1030115

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

High-throughput

0.513

High

1088105

UPP1
Uridine phosphorylase 1

1

0

High-throughput

0.513

High

1218916

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1237829

ENDOV
Endonuclease V

1

0

High-throughput

0.513

High

1300871

PIF1
ATP-dependent DNA helicase PIF1

1

0

High-throughput

0.513

High

1300881

FBX10
F-box only protein 10

1

0

High-throughput

0.513

High

278149

PIAS1
E3 SUMO-protein ligase PIAS1

1

2

Small-scale

0.501

High

360311

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

10

Small-scale

0.501

High

388669

HSPB1
Heat shock protein beta-1

1

9

Small-scale

0.501

High

409203

K2C8
Keratin, type II cytoskeletal 8

1

3

Small-scale

0.501

High

497468

TAU
Microtubule-associated protein tau

1

12

Small-scale

0.501

High

533724

GYS1
Glycogen [starch] synthase, muscle

1

1

Small-scale

0.501

High

537664

NCF1
Neutrophil cytosol factor 1

1

8

Small-scale

0.501

High

555741

F261
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

1

7

Small-scale

0.501

High

595368

LMNB1
Lamin-B1

1

10

Small-scale

0.501

High

655446

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

9

Small-scale

0.501

High

857940

PDX1
Pancreas/duodenum homeobox protein 1

1

2

Small-scale

0.501

High

932830

EF1A1
Elongation factor 1-alpha 1

1

3

Small-scale

0.501

High

1060279

NFAC4
Nuclear factor of activated T-cells, cytoplasmic 4

1

2

Small-scale

0.501

High

1083721

FRDA
Frataxin, mitochondrial

1

1

Small-scale

0.501

High

1167464

RFIP1
Rab11 family-interacting protein 1

1

7

Small-scale

0.501

High

1300874

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

Small-scale

0.501

High

885349

INHBE
Inhibin beta E chain

1

1

High-throughput

0.489

High

1157958

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

2

High-throughput

0.489

High

1176299

ATS13
A disintegrin and metalloproteinase with thrombospondin motifs 13

1

2

High-throughput

0.489

High

1231776

FA43A
Protein FAM43A

1

4

High-throughput

0.489

High

1251835

F110D
Protein FAM110D

1

1

High-throughput

0.489

High

1300867

WN10A
Protein Wnt-10a

1

3

High-throughput

0.489

High

1300869

KLK15
Kallikrein-15

1

3

High-throughput

0.489

High

1300882

TF3C4
General transcription factor 3C polypeptide 4

1

1

High-throughput

0.489

High

1300886

CCL26
C-C motif chemokine 26

1

1

High-throughput

0.489

High

163169

XPO1
Exportin-1

1

5

High-throughput

0.479

High

164456

TRI66
Tripartite motif-containing protein 66

1

7

High-throughput

0.479

High

212660

AP1G1
AP-1 complex subunit gamma-1

1

5

High-throughput

0.479

High

272930

RFPL2
Ret finger protein-like 2

1

4

High-throughput

0.479

High

300238

PRP6
Pre-mRNA-processing factor 6

1

1

High-throughput

0.479

High

575827

VINC
Vinculin

1

3

High-throughput

0.479

High

840560

VASP
Vasodilator-stimulated phosphoprotein

1

2

High-throughput

0.479

High

1042337

CUL3
Cullin-3

1

8

High-throughput

0.479

High

1052136

MAP7
Ensconsin

1

9

High-throughput

0.479

High

1146755

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.479

High

1147700

TENS3
Tensin-3

1

1

High-throughput

0.479

High

1201445

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

6

High-throughput

0.479

High

1267849

CNOT9
CCR4-NOT transcription complex subunit 9

1

2

High-throughput

0.479

High

1271237

GOGA1
Golgin subfamily A member 1

1

9

High-throughput

0.479

High

1272002

RAD50
DNA repair protein RAD50

1

12

High-throughput

0.479

High

1300872

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1300884

AGO1
Protein argonaute-1

1

9

High-throughput

0.479

High

1300890

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

1

High-throughput

0.479

High

203160

P52K
52 kDa repressor of the inhibitor of the protein kinase

1

0

High-throughput

0.458

High

305803

ELP1
Elongator complex protein 1

1

0

High-throughput

0.458

High

1039295

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

1115660

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.458

High

1132156

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

1

0

High-throughput

0.458

High

1204314

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

1241363

HJURP
Holliday junction recognition protein

1

0

High-throughput

0.458

High

1293588

SENP5
Sentrin-specific protease 5

1

0

High-throughput

0.458

High

1300865

B9D2
B9 domain-containing protein 2

1

0

High-throughput

0.458

High

1300866

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

1300877

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.458

High

361777

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

1

Small-scale

0.457

High

1125217

NOM1
Nucleolar MIF4G domain-containing protein 1

1

2

High-throughput

0.437

High

1300862

DCR1C
Protein artemis

1

1

High-throughput

0.437

High

1300879

UVRAG
UV radiation resistance-associated gene protein

1

0

High-throughput

0.426

High

1300873

CG069
Putative uncharacterized protein PKD1L1-AS1

2

0

High-throughput

0.328

High

1264925

DNS2B
Deoxyribonuclease-2-beta

2

0

High-throughput

0.318

High

67768

ZBBX
Zinc finger B-box domain-containing protein 1

1

0

High-throughput

0.279

Low

312836

CCN6
Cellular communication network factor 6

1

0

High-throughput

0.279

Low

960730

NDP
Norrin

1

0

High-throughput

0.279

Low

1032350

MFAP5
Microfibrillar-associated protein 5

1

0

High-throughput

0.279

Low

1089441

ODAPH
Odontogenesis associated phosphoprotein

1

0

High-throughput

0.279

Low

1132355

F120S
Uncharacterized protein FAM120AOS

1

0

High-throughput

0.279

Low

1221047

IQCF2
IQ domain-containing protein F2

1

0

High-throughput

0.279

Low

1300875

IGSF5
Immunoglobulin superfamily member 5

1

0

High-throughput

0.279

Low

353085

IL2RA
Interleukin-2 receptor subunit alpha

1

0

Small-scale

0.261

Low

373057

VTNC
Vitronectin

1

0

Small-scale

0.261

Low

1137004

PR14L
Protein PRR14L

1

0

High-throughput

0.249

Low

1139551

SLX4I
Protein SLX4IP

1

0

Small-scale

0.249

Low

1259900

TF3C2
General transcription factor 3C polypeptide 2

1

0

High-throughput

0.249

Low

1300889

LAS1L
Ribosomal biogenesis protein LAS1L

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024