Protein: PPP5
Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PPT)

Gene: PPP5, Ppp5c
Organism: Mus musculus
Interactions: 89
UniProt ID: Q60676

Gene Ontology (top 5):
GO:0001965 - G-protein alpha-subunit binding
GO:0003723 - RNA binding
GO:0004721 - phosphoprotein phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

462116

HS90A
Heat shock protein HSP 90-alpha

1

12

High-throughput

0.618

High

465815

ENPL
Endoplasmin

1

10

Small-scale

0.618

High

547256

HS90B
Heat shock protein HSP 90-beta

1

13

High-throughput

0.618

High

1221303

PPP5
Serine/threonine-protein phosphatase 5

1

15

High-throughput

0.618

High

1221328

DGKG
Diacylglycerol kinase gamma

1

2

High-throughput

0.618

High

1221341

NOS1
Nitric oxide synthase 1

1

4

High-throughput

0.618

High

994003

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

14

Small-scale

0.590

High

1221334

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

3

Small-scale

0.589

High

771473

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

8

High-throughput

0.536

High

64308

RBG1L
Rab GTPase-activating protein 1-like

1

4

High-throughput

0.479

High

73898

PYR1
Multifunctional protein CAD

1

6

High-throughput

0.479

High

74310

TUT4
Terminal uridylyltransferase 4

1

1

High-throughput

0.479

High

92770

D3Z656
Synaptojanin-1

1

2

High-throughput

0.479

High

205387

NUDC
Nuclear migration protein nudC

1

4

High-throughput

0.479

High

205750

PER1
Period circadian protein homolog 1

1

12

High-throughput

0.479

High

312911

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

11

High-throughput

0.479

High

421228

ALDOA
Fructose-bisphosphate aldolase A

1

1

High-throughput

0.479

High

530816

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.479

High

548949

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

13

High-throughput

0.479

High

576879

MAP1B
Microtubule-associated protein 1B

1

17

High-throughput

0.479

High

578750

GLNA
Glutamine synthetase

1

1

High-throughput

0.479

High

586404

H12
Histone H1.2

1

3

High-throughput

0.479

High

631787

MTAP2
Microtubule-associated protein 2

1

20

High-throughput

0.479

High

693475

PLAP
Phospholipase A-2-activating protein

1

9

High-throughput

0.479

High

704215

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

13

High-throughput

0.479

High

845184

EAA2
Excitatory amino acid transporter 2

1

1

High-throughput

0.479

High

871194

DCE2
Glutamate decarboxylase 2

1

3

High-throughput

0.479

High

941871

EAA1
Excitatory amino acid transporter 1

1

1

High-throughput

0.479

High

949044

RUVB1
RuvB-like 1

1

9

High-throughput

0.479

High

959307

ABCE1
ATP-binding cassette sub-family E member 1

1

3

High-throughput

0.479

High

961458

RL27
Large ribosomal subunit protein eL27

1

2

High-throughput

0.479

High

982052

RL23
Large ribosomal subunit protein uL14

1

2

High-throughput

0.479

High

986306

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.479

High

987289

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

3

High-throughput

0.479

High

989249

HSP7C
Heat shock cognate 71 kDa protein

1

14

High-throughput

0.479

High

1029196

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

8

High-throughput

0.479

High

1033470

TERA
Transitional endoplasmic reticulum ATPase

1

10

High-throughput

0.479

High

1034646

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

3

High-throughput

0.479

High

1179277

GSK3A
Glycogen synthase kinase-3 alpha

1

17

High-throughput

0.479

High

1185242

OSBP1
Oxysterol-binding protein 1

1

2

High-throughput

0.479

High

1190082

NT5D3
5'-nucleotidase domain-containing protein 3

1

1

High-throughput

0.479

High

1190606

GRIN1
G protein-regulated inducer of neurite outgrowth 1

1

10

High-throughput

0.479

High

1221179

SRC8
Src substrate cortactin

1

11

High-throughput

0.479

High

1221304

PRDX2
Peroxiredoxin-2

1

1

High-throughput

0.479

High

1221306

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

3

High-throughput

0.479

High

1221309

Q6P5B5
FMR1 autosomal homolog 2

1

4

High-throughput

0.479

High

1221310

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

13

High-throughput

0.479

High

1221311

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme UBE2O

1

8

High-throughput

0.479

High

1221312

NP1L4
Nucleosome assembly protein 1-like 4

1

4

High-throughput

0.479

High

1221314

IF4G3
Eukaryotic translation initiation factor 4 gamma 3

1

2

High-throughput

0.479

High

1221316

DLGP2
Disks large-associated protein 2

1

7

High-throughput

0.479

High

1221319

Q8BVQ9
26S proteasome regulatory subunit 7

1

2

High-throughput

0.479

High

1221323

WDR47
WD repeat-containing protein 47

1

13

High-throughput

0.479

High

1221325

ZNFX1
NFX1-type zinc finger-containing protein 1

1

5

High-throughput

0.479

High

1221327

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

6

High-throughput

0.479

High

1221329

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

13

High-throughput

0.479

High

1221330

ARBK1
Beta-adrenergic receptor kinase 1

1

13

High-throughput

0.479

High

1221332

ACBG1
Long-chain-fatty-acid--CoA ligase ACSBG1

1

1

High-throughput

0.479

High

1221333

SGT1
Protein SGT1 homolog

1

12

High-throughput

0.479

High

1221335

RUFY3
Protein RUFY3

1

4

High-throughput

0.479

High

1221337

APBB1
Amyloid beta precursor protein binding family B member 1

1

2

High-throughput

0.479

High

1221338

MAP1A
Microtubule-associated protein 1A

1

9

High-throughput

0.479

High

1221339

RUVB2
RuvB-like 2

1

9

High-throughput

0.479

High

1221342

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

9

High-throughput

0.479

High

1221343

NFS1
Cysteine desulfurase

1

1

High-throughput

0.479

High

1000376

IDHG1
Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial

1

0

High-throughput

0.458

High

1071123

KNDC1
Kinase non-catalytic C-lobe domain-containing protein 1

1

0

High-throughput

0.458

High

1221313

CAPS1
Calcium-dependent secretion activator 1

1

0

High-throughput

0.458

High

1221322

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.458

High

1221326

TCF25
Ribosome quality control complex subunit TCF25

1

0

High-throughput

0.458

High

1221331

SCD3
Acyl-CoA desaturase 3

1

0

High-throughput

0.458

High

72849

B0V2P5
Dmx-like 2

1

6

High-throughput

0.437

High

871192

DCE1
Glutamate decarboxylase 1

1

3

High-throughput

0.437

High

1021286

VPS45
Vacuolar protein sorting-associated protein 45

1

2

High-throughput

0.437

High

1021881

XRN1
5'-3' exoribonuclease 1

1

2

High-throughput

0.437

High

1135206

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

1

3

High-throughput

0.437

High

1190046

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

4

High-throughput

0.437

High

1221305

SERA
D-3-phosphoglycerate dehydrogenase

1

5

High-throughput

0.437

High

1221308

SPKAP
A-kinase anchor protein SPHKAP

1

4

High-throughput

0.437

High

1221315

ATG2B
Autophagy-related protein 2 homolog B

1

2

High-throughput

0.437

High

1221318

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

6

High-throughput

0.437

High

1221320

ASGL1
Isoaspartyl peptidase/L-asparaginase

1

2

High-throughput

0.437

High

1221321

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

13

High-throughput

0.437

High

1221324

NAV1
Neuron navigator 1

1

12

High-throughput

0.437

High

1221336

RTN3
Reticulon-3

1

4

High-throughput

0.437

High

1221340

COR1C
Coronin-1C

1

12

High-throughput

0.437

High

1221307

FBX41
F-box only protein 41

1

0

High-throughput

0.249

Low

1221317

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025