Protein: UBP1
Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (hUBP) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) [Cleaved into: Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment]

Gene: UBP1, USP1
Organism: Homo sapiens
Interactions: 115
UniProt ID: O94782

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

296325

WDR48
WD repeat-containing protein 48

25

18

Small-scale

0.992

High

296342

FACD2
Fanconi anemia group D2 protein

8

4

Small-scale

0.967

High

296262

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

4

20

Small-scale

0.888

High

296351

FZR1
Fizzy-related protein homolog

2

12

Small-scale

0.806

High

232750

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

8

11

Small-scale

0.754

High

296265

PCNA
Proliferating cell nuclear antigen

8

1

Small-scale

0.751

High

296281

IMA5
Importin subunit alpha-5

5

10

Small-scale

0.726

High

296348

FANCI
Fanconi anemia group I protein

4

1

Small-scale

0.694

High

296332

R51A1
RAD51-associated protein 1

4

2

Small-scale

0.694

High

296278

BAG6
Large proline-rich protein BAG6

1

11

High-throughput

0.691

High

296318

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

19

High-throughput

0.691

High

296297

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

18

High-throughput

0.665

High

296317

PHLP2
PH domain leucine-rich repeat-containing protein phosphatase 2

3

9

Small-scale

0.662

High

296282

STAT2
Signal transducer and activator of transcription 2

2

4

High-throughput

0.628

High

296257

MYC
Myc proto-oncogene protein

2

13

Small-scale

0.624

High

259256

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

18

High-throughput

0.618

High

296253

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

18

Small-scale

0.618

High

296289

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

17

High-throughput

0.618

High

296327

WDR20
WD repeat-containing protein 20

1

20

High-throughput

0.618

High

296347

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.618

High

147466

SOCS6
Suppressor of cytokine signaling 6

2

7

High-throughput

0.611

High

296306

IMB1
Importin subunit beta-1

2

3

Small-scale

0.611

High

296352

KLDC2
Kelch domain-containing protein 2

2

10

Small-scale

0.608

High

296336

ATAD5
ATPase family AAA domain-containing protein 5

2

7

Small-scale

0.584

High

296330

LRC15
Leucine-rich repeat-containing protein 15

2

6

High-throughput

0.574

High

177571

BCAT2
Branched-chain-amino-acid aminotransferase, mitochondrial

1

2

Small-scale

0.561

High

296287

MAX
Protein max

1

13

Small-scale

0.561

High

296309

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

Small-scale

0.561

High

296346

NMRL1
NmrA-like family domain-containing protein 1

1

2

High-throughput

0.561

High

296267

EZRI
Ezrin

1

1

High-throughput

0.541

High

235631

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

3

High-throughput

0.536

High

296280

IMA1
Importin subunit alpha-1

1

10

High-throughput

0.536

High

296311

SGO1
Shugoshin 1

1

2

High-throughput

0.536

High

296337

SORT
Sortilin

1

1

High-throughput

0.536

High

296310

TAZ
Tafazzin

2

2

Small-scale

0.533

High

296260

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.515

High

296266

PLAK
Junction plakoglobin

1

18

High-throughput

0.515

High

296269

FILA
Filaggrin

1

12

High-throughput

0.515

High

296274

MYH9
Myosin-9

1

12

High-throughput

0.515

High

296275

TAGL2
Transgelin-2

1

3

High-throughput

0.515

High

296279

LEG7
Galectin-7

1

2

High-throughput

0.515

High

296294

DSG1
Desmoglein-1

1

4

High-throughput

0.515

High

296295

K1C17
Keratin, type I cytoskeletal 17

1

11

High-throughput

0.515

High

296303

PKP1
Plakophilin-1

1

14

High-throughput

0.515

High

296312

TOIP1
Torsin-1A-interacting protein 1

1

0

High-throughput

0.513

High

296340

RSRP1
Arginine/serine-rich protein 1

1

0

High-throughput

0.513

High

296345

PGES2
Prostaglandin E synthase 2

1

0

High-throughput

0.513

High

296286

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

5

Small-scale

0.501

High

265381

KTNA1
Katanin p60 ATPase-containing subunit A1

1

7

High-throughput

0.489

High

296272

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

296313

SPXN5
Sperm protein associated with the nucleus on the X chromosome N5

1

1

High-throughput

0.489

High

296314

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

2

High-throughput

0.489

High

296320

UBE3B
Ubiquitin-protein ligase E3B

1

14

High-throughput

0.489

High

296326

ZCH10
Zinc finger CCHC domain-containing protein 10

1

1

High-throughput

0.489

High

296334

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

10

High-throughput

0.489

High

296335

OPALI
Opalin

1

2

High-throughput

0.489

High

296324

DTX3
Probable E3 ubiquitin-protein ligase DTX3

1

5

High-throughput

0.481

High

296341

PHF7
PHD finger protein 7

1

8

High-throughput

0.481

High

296353

TRAF6
TNF receptor-associated factor 6

1

20

High-throughput

0.481

High

296254

UFL1
E3 UFM1-protein ligase 1

1

0

Small-scale

0.480

High

64109

AXA2L
Putative annexin A2-like protein

1

2

High-throughput

0.479

High

69187

IMA8
Importin subunit alpha-8

1

10

Small-scale

0.479

High

123812

SPT5H
Transcription elongation factor SPT5

1

2

Small-scale

0.479

High

131355

IMA4
Importin subunit alpha-4

1

10

Small-scale

0.479

High

168606

IMA6
Importin subunit alpha-6

1

10

Small-scale

0.479

High

262206

ULK1
Serine/threonine-protein kinase ULK1

1

7

Small-scale

0.479

High

296255

NFAT5
Nuclear factor of activated T-cells 5

1

4

Small-scale

0.479

High

296256

SNAI1
Zinc finger protein SNAI1

1

9

Small-scale

0.479

High

296258

ESR1
Estrogen receptor

1

14

Small-scale

0.479

High

296259

CPNS1
Calpain small subunit 1

1

3

Small-scale

0.479

High

296261

PARP1
Poly [ADP-ribose] polymerase 1

1

9

Small-scale

0.479

High

296263

KIT
Mast/stem cell growth factor receptor Kit

1

1

Small-scale

0.479

High

296264

BCR
Breakpoint cluster region protein

1

5

Small-scale

0.479

High

296268

K2C4
Keratin, type II cytoskeletal 4

1

5

High-throughput

0.479

High

296271

AKT1
RAC-alpha serine/threonine-protein kinase

1

6

Small-scale

0.479

High

296273

HNRH3
Heterogeneous nuclear ribonucleoprotein H3

1

9

Small-scale

0.479

High

296276

GRP75
Stress-70 protein, mitochondrial

1

12

Small-scale

0.479

High

296277

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

296283

PLK1
Serine/threonine-protein kinase PLK1

1

13

Small-scale

0.479

High

296284

CTBP2
C-terminal-binding protein 2

1

1

High-throughput

0.479

High

296285

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

8

High-throughput

0.479

High

296290

RS16
Small ribosomal subunit protein uS9

1

4

Small-scale

0.479

High

296291

RS18
Small ribosomal subunit protein uS13

1

3

Small-scale

0.479

High

296292

RS4X
Small ribosomal subunit protein eS4, X isoform

1

3

Small-scale

0.479

High

296293

ID2
DNA-binding protein inhibitor ID-2

1

3

Small-scale

0.479

High

296298

TRAF3
TNF receptor-associated factor 3

1

20

Small-scale

0.479

High

296300

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

7

Small-scale

0.479

High

296301

CUL1
Cullin-1

1

9

Small-scale

0.479

High

296302

CUL4A
Cullin-4A

1

9

High-throughput

0.479

High

296304

CIRBP
Cold-inducible RNA-binding protein

1

5

High-throughput

0.479

High

296305

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

10

Small-scale

0.479

High

296307

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

12

Small-scale

0.479

High

296308

SIX1
Homeobox protein SIX1

1

2

Small-scale

0.479

High

296319

SPT6H
Transcription elongation factor SPT6

1

2

Small-scale

0.479

High

296331

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

2

Small-scale

0.479

High

296338

VRK1
Serine/threonine-protein kinase VRK1

1

2

Small-scale

0.479

High

296339

AN32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E

1

3

Small-scale

0.479

High

296343

WWTR1
WW domain-containing transcription regulator protein 1

1

18

Small-scale

0.479

High

296344

APC1
Anaphase-promoting complex subunit 1

1

1

Small-scale

0.479

High

296350

TBK1
Serine/threonine-protein kinase TBK1

1

9

Small-scale

0.479

High

296270

CALL3
Calmodulin-like protein 3

1

3

High-throughput

0.470

High

296288

LYSC
Lysozyme C

1

1

High-throughput

0.470

High

296296

DSC1
Desmocollin-1

1

2

High-throughput

0.470

High

296323

A16A1
Aldehyde dehydrogenase family 16 member A1

1

2

High-throughput

0.470

High

296349

CALL5
Calmodulin-like protein 5

1

3

High-throughput

0.470

High

296322

TM192
Transmembrane protein 192

1

0

Small-scale

0.458

High

296321

TRI46
Tripartite motif-containing protein 46

1

20

High-throughput

0.439

High

150142

AP3D1
AP-3 complex subunit delta-1

1

3

Small-scale

0.437

High

296299

OS9
Protein OS-9

1

1

Small-scale

0.437

High

296315

CHIC1
Cysteine-rich hydrophobic domain-containing protein 1

1

0

High-throughput

0.279

Low

296328

CERK1
Ceramide kinase

1

0

High-throughput

0.279

Low

296329

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

296316

GOLM2
Protein GOLM2

1

0

Small-scale

0.249

Low

296333

ZN428
Zinc finger protein 428

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024