Protein: LIN2
Protein lin-2 (Abnormal cell lineage protein 2)

Gene: LIN2, lin-2
Organism: Caenorhabditis elegans
Interactions: 75
UniProt ID: P54936

Gene Ontology (top 5):
GO:0004713 - protein tyrosine kinase activity
GO:0005102 - signaling receptor binding
GO:0005159 - insulin-like growth factor receptor binding
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

873636

Q9U245
Protein lin-7 homolog

6

20

Small-scale

0.947

High

184588

LIN10
Protein lin-10

6

20

Small-scale

0.945

High

105688

G5ED33
Epidermal growth factor receptor pathway substrate 8 splice variant A

4

4

Small-scale

0.875

High

528290

GLP1
Protein glp-1 [Cleaved into: glp-1/Notch intracellular domain]

2

5

High-throughput

0.743

High

873612

SPK1
Serine/threonine-protein kinase spk-1

2

10

High-throughput

0.743

High

107539

UBQL
Ubiquilin

3

7

High-throughput

0.733

High

619838

UN104
Kinesin-like protein unc-104

1

14

Small-scale

0.713

High

873620

LIPA
Liprin-alpha

1

6

Small-scale

0.713

High

873634

INSR
Insulin-like receptor

1

20

Small-scale

0.621

High

108104

HIF1
Hypoxia-inducible factor 1

3

1

High-throughput

0.599

High

567376

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

3

1

High-throughput

0.599

High

712124

YMV2
Uncharacterized protein K04H4.2

3

6

High-throughput

0.599

High

873613

Q17746
ZZ-type domain-containing protein

3

3

High-throughput

0.599

High

873625

MIG5
Segment polarity protein dishevelled homolog mig-5

1

20

High-throughput

0.590

High

284139

PPN1
Papilin

1

4

High-throughput

0.587

High

218387

O44444
RRM domain-containing protein

1

0

High-throughput

0.584

High

64258

A6PVA5
ATP synthase subunit s, mitochondrial

3

1

High-throughput

0.583

High

713374

KTNA1
Meiotic spindle formation protein mei-1

2

1

High-throughput

0.576

High

741930

UNC87
Protein unc-87

2

2

High-throughput

0.559

High

873635

Q9TZK8
J domain-containing protein

2

1

High-throughput

0.553

High

103922

G5EBE3
CBF1-interacting co-repressor CIR N-terminal domain-containing protein

2

1

High-throughput

0.542

High

873614

Q17796
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

4

High-throughput

0.542

High

873629

TOP2
DNA topoisomerase 2 top-2

1

1

High-throughput

0.541

High

218667

O44490
ELKS/RAB6-interacting/CAST family member 2

2

5

High-throughput

0.533

High

186267

O18672
F15C11.2

1

12

High-throughput

0.528

High

873616

Q18529
Chitin-binding type-2 domain-containing protein

2

7

High-throughput

0.526

High

873622

Q21225
Protein VAC14 homolog

2

1

High-throughput

0.526

High

873638

LIN41
Protein lin-41

2

9

High-throughput

0.526

High

873639

OSTA3
Organic solute transporter alpha-like protein 3

1

0

High-throughput

0.518

High

136256

O01331
Galectin

1

4

High-throughput

0.494

High

110527

H2L2C8
Alpha-actinin, sarcomeric

1

14

High-throughput

0.481

High

184973

O17905
Moesin/ezrin/radixin homolog 1

1

20

Small-scale

0.481

High

873626

Q22387
Centrosomal protein of 162 kDa

1

2

High-throughput

0.464

High

873627

Q23158
Alpha-actinin, sarcomeric

1

14

High-throughput

0.457

High

873641

Q9XVU8
Alpha-actinin, sarcomeric

1

14

High-throughput

0.457

High

87667

D0IMZ6
FiLamiN

1

4

High-throughput

0.439

High

107588

G5EFG1
PDZ and LIM domain protein Zasp

1

2

High-throughput

0.439

High

185085

O17977
Cell wall protein DAN4

1

1

High-throughput

0.439

High

218216

HMP2
Beta-catenin-like protein hmp-2

1

6

High-throughput

0.439

High

873623

EPI1
Laminin-like protein epi-1

1

10

High-throughput

0.439

High

873630

Q564V2
Lateral Signaling Target

1

1

High-throughput

0.439

High

91823

E9P875
Neurexin-3-beta

1

1

High-throughput

0.437

High

81072

B7WNA3
Cell wall protein DAN4

1

1

High-throughput

0.417

High

87659

D0IMZ5
Calponin-homology

1

16

High-throughput

0.417

High

107188

G5EEV6
Laminin alpha

1

10

High-throughput

0.417

High

110590

H2L2I2
Armadillo/beta-catenin-like repeat protein

1

6

High-throughput

0.417

High

183822

O16314
ATP synthase subunit s, mitochondrial

1

1

High-throughput

0.417

High

873611

P91820
Lateral Signaling Target

1

1

High-throughput

0.417

High

873619

VPS39
Vacuolar protein sorting-associated protein 39 homolog

1

7

High-throughput

0.417

High

873617

Q18624
SAND domain-containing protein

5

0

High-throughput

0.375

High

247687

O61711
RRM domain-containing protein

3

0

High-throughput

0.342

High

711220

TYR1
Putative tyrosinase-like protein tyr-1

3

0

High-throughput

0.342

High

712494

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

3

0

High-throughput

0.342

High

804450

SUMV1
Protein sumv-1

3

0

High-throughput

0.342

High

873624

MEP1
MOG interacting and ectopic P-granules protein 1

3

0

High-throughput

0.342

High

873631

Q93831
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

3

0

High-throughput

0.342

High

220402

CPL1
Cathepsin L-like

2

0

High-throughput

0.300

High

712356

EI2BA
Translation initiation factor eIF2B subunit alpha

2

0

High-throughput

0.300

High

873632

HYLS1
Centriolar and ciliogenesis-associated protein hyls-1

2

0

High-throughput

0.300

High

873637

GYS
Glycogen [starch] synthase

2

0

High-throughput

0.300

High

105846

G5ED81
C09G4.4 protein

1

0

High-throughput

0.282

High

183670

O16208
PAN-3 domain-containing protein

1

0

High-throughput

0.282

High

283807

O76412
G_PROTEIN_RECEP_F1_2 domain-containing protein

1

0

High-throughput

0.282

High

873615

Q18238
Intrinsically Disordered Protein, class B

1

0

High-throughput

0.282

High

873618

NDUS6
Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.282

High

873621

Q21083
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.282

High

873628

Q23615
SXP/RAL-2 family protein Ani s 5-like cation-binding domain-containing protein

1

0

High-throughput

0.282

High

873633

Q95YA5
DYnein Light chain, Axonemal p28 type

1

0

High-throughput

0.282

High

873640

Q9XV58
ShKT domain-containing protein

1

0

High-throughput

0.282

High

410534

VIT5
Vitellogenin-5

1

0

High-throughput

0.265

Low

81077

B7WNB1
Geranylgeranyl transferase type I subunit beta

1

0

High-throughput

0.251

Low

82887

B9WRT8
C3H1-type domain-containing protein

1

0

High-throughput

0.251

Low

103466

G4SL51
DUF1080 domain-containing protein

1

0

High-throughput

0.251

Low

81074

B7WNB0
Geranylgeranyl transferase type I subunit beta

1

0

High-throughput

0.238

Low

218138

O44144
PERMeable eggshell

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024