Protein: SOCS7
Suppressor of cytokine signaling 7 (SOCS-7) (Nck, Ash and phospholipase C gamma-binding protein) (Nck-associated protein 4) (NAP-4)

Gene: SOCS7
Organism: Homo sapiens
Interactions: 42
UniProt ID: O14512

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005942 - phosphatidylinositol 3-kinase complex
GO:0009968 - negative regulation of signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

146692

CUL5
Cullin-5

5

20

Small-scale

0.927

High

146664

VINEX
Vinexin

3

9

Small-scale

0.864

High

146669

NCK1
SH2/SH3 adapter protein NCK1

3

20

Small-scale

0.858

High

146663

NCK2
Cytoplasmic protein NCK2

3

20

High-throughput

0.858

High

146666

SRBS2
Sorbin and SH3 domain-containing protein 2

2

20

High-throughput

0.783

High

146668

YES
Tyrosine-protein kinase Yes

2

20

High-throughput

0.783

High

146674

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.783

High

146680

TENS2
Tensin-2

2

8

High-throughput

0.783

High

146671

STAT3
Signal transducer and activator of transcription 3

1

18

Small-scale

0.740

High

146696

KPCD2
Serine/threonine-protein kinase D2

1

10

High-throughput

0.691

High

146686

ABI1
Abl interactor 1

1

16

Small-scale

0.647

High

146683

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

12

High-throughput

0.621

High

146691

OSTF1
Osteoclast-stimulating factor 1

1

18

High-throughput

0.621

High

146662

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

20

Small-scale

0.618

High

146667

INSR
Insulin receptor

1

20

Small-scale

0.618

High

146672

STA5A
Signal transducer and activator of transcription 5A

1

18

Small-scale

0.618

High

146678

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

15

Small-scale

0.618

High

146688

GA2L2
GAS2-like protein 2

2

1

High-throughput

0.606

High

146695

MDFI
MyoD family inhibitor

2

1

High-throughput

0.606

High

146700

HSPB8
Heat shock protein beta-8

2

2

High-throughput

0.606

High

146681

NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor

2

0

High-throughput

0.580

High

146685

MISP
Mitotic interactor and substrate of PLK1

2

0

High-throughput

0.580

High

146693

EXOS8
Exosome complex component RRP43

2

0

High-throughput

0.580

High

146694

LENG8
Leukocyte receptor cluster member 8

2

0

High-throughput

0.580

High

146665

DAB1
Disabled homolog 1

1

16

Small-scale

0.536

High

146677

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.536

High

146687

KBTB8
Kelch repeat and BTB domain-containing protein 8

1

3

High-throughput

0.536

High

146697

JMJD4
2-oxoglutarate and iron-dependent oxygenase JMJD4

1

1

High-throughput

0.536

High

146698

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

10

High-throughput

0.536

High

146699

RBX2
RING-box protein 2

1

8

High-throughput

0.536

High

146701

CE164
Centrosomal protein of 164 kDa

1

6

High-throughput

0.536

High

146673

DCAF7
DDB1- and CUL4-associated factor 7

1

0

High-throughput

0.513

High

146675

SEPT6
Septin-6

1

2

Small-scale

0.506

High

146689

FAT3
Protocadherin Fat 3

1

11

High-throughput

0.489

High

146690

K0232
Uncharacterized protein KIAA0232

1

1

High-throughput

0.489

High

146702

CRBG1
Beta/gamma crystallin domain-containing protein 1

1

1

High-throughput

0.489

High

146670

IRS1
Insulin receptor substrate 1

1

20

Small-scale

0.479

High

146676

ELOB
Elongin-B

1

10

High-throughput

0.479

High

146679

ELAV1
ELAV-like protein 1

1

0

Small-scale

0.458

High

66899

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

146682

XIRP1
Xin actin-binding repeat-containing protein 1

1

0

High-throughput

0.279

Low

146684

P3H3
Prolyl 3-hydroxylase 3

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024