Protein: APC11
Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein)

Gene: APC11, ANAPC11
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q9NYG5

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

135955

UBE2C
Ubiquitin-conjugating enzyme E2 C

64

20

Small-scale

0.997

High

1086928

UBE2S
Ubiquitin-conjugating enzyme E2 S

31

20

Small-scale

0.993

High

919882

UB2D2
Ubiquitin-conjugating enzyme E2 D2

11

20

Small-scale

0.975

High

849463

UB2D1
Ubiquitin-conjugating enzyme E2 D1

5

20

Small-scale

0.919

High

1348495

ANC2
Anaphase-promoting complex subunit 2

5

20

Small-scale

0.916

High

896388

UBE2K
Ubiquitin-conjugating enzyme E2 K

3

20

Small-scale

0.845

High

895932

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

Small-scale

0.778

High

1348490

APC11
Anaphase-promoting complex subunit 11

2

6

Small-scale

0.778

High

1274066

CUL5
Cullin-5

2

20

Small-scale

0.757

High

476475

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

3

Small-scale

0.755

High

1348494

APC4
Anaphase-promoting complex subunit 4

8

1

Small-scale

0.746

High

672906

CDC27
Cell division cycle protein 27 homolog

7

8

Small-scale

0.735

High

1017448

CDC20
Cell division cycle protein 20 homolog

4

4

Small-scale

0.683

High

1238837

IQUB
IQ motif and ubiquitin-like domain-containing protein

2

0

High-throughput

0.655

High

330213

PTTG1
Securin

3

0

Small-scale

0.627

High

1138924

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.625

High

1344010

BIRC6
Baculoviral IAP repeat-containing protein 6

1

20

Small-scale

0.618

High

212532

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

1

High-throughput

0.606

High

871491

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

1

High-throughput

0.606

High

973647

CREB5
Cyclic AMP-responsive element-binding protein 5

2

3

High-throughput

0.606

High

1317358

KRA33
Keratin-associated protein 3-3

2

1

High-throughput

0.606

High

1317382

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.606

High

1348497

FZR1
Fizzy-related protein homolog

2

4

Small-scale

0.595

High

993629

TLE5
TLE family member 5

2

0

High-throughput

0.580

High

1109097

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.580

High

1109166

KRA61
Keratin-associated protein 6-1

2

0

High-throughput

0.580

High

1109272

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.580

High

1119881

KR132
Keratin-associated protein 13-2

2

0

High-throughput

0.580

High

1200359

DTX2
Probable E3 ubiquitin-protein ligase DTX2

2

0

High-throughput

0.580

High

1216026

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.580

High

1237651

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

0

High-throughput

0.580

High

1238537

BANP
Protein BANP

2

0

High-throughput

0.580

High

1274264

RBPMS
RNA-binding protein with multiple splicing

2

0

High-throughput

0.580

High

1297298

SMIP9
Protein SPMIP9

2

0

High-throughput

0.580

High

1348491

WWOX
WW domain-containing oxidoreductase

2

0

High-throughput

0.580

High

327116

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

3

High-throughput

0.553

High

328060

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

2

2

High-throughput

0.553

High

1017000

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

2

2

High-throughput

0.553

High

1255387

OXER1
Oxoeicosanoid receptor 1

2

2

High-throughput

0.553

High

1329303

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

2

1

High-throughput

0.553

High

1023005

CDC16
Cell division cycle protein 16 homolog

2

10

High-throughput

0.552

High

595758

MAK
Serine/threonine-protein kinase MAK

1

1

High-throughput

0.541

High

1162064

TRI65
E3 ubiquitin-protein ligase TRIM65

1

1

High-throughput

0.541

High

1169194

RN111
E3 ubiquitin-protein ligase Arkadia

1

3

High-throughput

0.541

High

153181

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

2

High-throughput

0.536

High

587027

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.536

High

796486

ZAP70
Tyrosine-protein kinase ZAP-70

1

0

High-throughput

0.518

High

1239422

MLKL
Mixed lineage kinase domain-like protein

1

0

High-throughput

0.518

High

218080

PEX1
Peroxisomal ATPase PEX1

1

6

High-throughput

0.515

High

1306710

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.513

High

391939

H2A1B
Histone H2A type 1-B/E

1

4

Small-scale

0.501

High

538617

CCNB1
G2/mitotic-specific cyclin-B1

1

2

Small-scale

0.501

High

707769

H2B1B
Histone H2B type 1-B

1

2

Small-scale

0.501

High

1348496

FBX5
F-box only protein 5

1

1

Small-scale

0.501

High

1348498

APC10
Anaphase-promoting complex subunit 10

1

6

Small-scale

0.501

High

935308

H31
Histone H3.1

1

0

Small-scale

0.480

High

590227

CCNA2
Cyclin-A2

1

2

Small-scale

0.479

High

963691

E2F1
Transcription factor E2F1

1

1

Small-scale

0.479

High

1140813

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

1348492

HERC5
E3 ISG15--protein ligase HERC5

1

3

Small-scale

0.479

High

978918

TF65
Transcription factor p65

1

0

Small-scale

0.458

High

1348493

CDC23
Cell division cycle protein 23 homolog

1

10

High-throughput

0.445

High

67381

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

207385

FRS3
Fibroblast growth factor receptor substrate 3

2

0

High-throughput

0.316

High

863880

CRBA2
Beta-crystallin A2

2

0

High-throughput

0.316

High

1190523

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

0

High-throughput

0.316

High

1242766

BEND2
BEN domain-containing protein 2

2

0

High-throughput

0.316

High

1348499

CAN11
Calpain-11

1

0

High-throughput

0.282

High

943623

S35B1
Solute carrier family 35 member B1

1

0

High-throughput

0.279

Low

1266504

YLAT2
Y+L amino acid transporter 2

1

0

High-throughput

0.279

Low

660733

GRN
Progranulin

1

0

High-throughput

0.268

Low

1113775

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

1281143

NKD2
Protein naked cuticle homolog 2

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024