Protein: CYTN
Cystatin-SN (Cystain-SA-I) (Cystatin-1) (Salivary cystatin-SA-1)

Gene: CYTN, CST1
Organism: Homo sapiens
Interactions: 142
UniProt ID: P01037

Gene Ontology (top 5):
GO:0001580 - detection of chemical stimulus involved in sensory perception of bitter taste
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0031982 - vesicle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

344837

CYTS
Cystatin-S

3

2

Small-scale

0.861

High

245770

CATL2
Cathepsin L2

2

13

High-throughput

0.811

High

344922

CATL1
Procathepsin L

2

13

High-throughput

0.811

High

344926

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

2

13

High-throughput

0.811

High

345001

UBTD2
Ubiquitin domain-containing protein 2

3

1

High-throughput

0.667

High

345021

GKN1
Gastrokine-1

2

1

High-throughput

0.628

High

344912

CYTN
Cystatin-SN

1

2

Small-scale

0.618

High

345010

LGMN
Legumain

1

3

Small-scale

0.618

High

274677

B3GL1
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

3

4

High-throughput

0.609

High

344967

TF2B
Transcription initiation factor IIB

3

2

High-throughput

0.609

High

345028

UBQL2
Ubiquilin-2

2

1

High-throughput

0.606

High

345026

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

2

0

High-throughput

0.602

High

344964

CSK2B
Casein kinase II subunit beta

2

0

High-throughput

0.580

High

159449

QCR8
Cytochrome b-c1 complex subunit 8

2

1

High-throughput

0.574

High

297563

RHBT1
Rho-related BTB domain-containing protein 1

2

3

High-throughput

0.574

High

344963

RUXF
Small nuclear ribonucleoprotein F

2

2

High-throughput

0.574

High

344984

PKHG6
Pleckstrin homology domain-containing family G member 6

2

3

High-throughput

0.574

High

344999

FRMD1
FERM domain-containing protein 1

2

3

High-throughput

0.574

High

345019

DDX31
ATP-dependent DNA helicase DDX31

2

3

High-throughput

0.574

High

213433

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

2

High-throughput

0.573

High

344951

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

2

3

High-throughput

0.558

High

345000

KCNG4
Potassium voltage-gated channel subfamily G member 4

2

2

High-throughput

0.558

High

345006

HVCN1
Voltage-gated hydrogen channel 1

2

1

High-throughput

0.558

High

345020

TNR19
Tumor necrosis factor receptor superfamily member 19

2

2

Small-scale

0.558

High

127656

CCRL2
C-C chemokine receptor-like 2

1

4

High-throughput

0.536

High

158081

TX1B3
Tax1-binding protein 3

1

3

High-throughput

0.536

High

177640

BIRC5
Baculoviral IAP repeat-containing protein 5

1

1

High-throughput

0.536

High

344914

FRIH
Ferritin heavy chain

1

3

High-throughput

0.536

High

344920

CRF
Corticoliberin

1

2

High-throughput

0.536

High

344944

UFO
Tyrosine-protein kinase receptor UFO

1

6

High-throughput

0.536

High

344956

MP2K6
Dual specificity mitogen-activated protein kinase kinase 6

1

1

High-throughput

0.536

High

344960

ARP3
Actin-related protein 3

1

1

High-throughput

0.536

High

344975

DAZ2
Deleted in azoospermia protein 2

1

2

High-throughput

0.536

High

344979

RCAN2
Calcipressin-2

1

5

High-throughput

0.536

High

344982

STK11
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.536

High

344990

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

1

High-throughput

0.536

High

344993

KCC1D
Calcium/calmodulin-dependent protein kinase type 1D

1

1

High-throughput

0.536

High

344997

COMD1
COMM domain-containing protein 1

1

2

High-throughput

0.536

High

345002

CHAC2
Glutathione-specific gamma-glutamylcyclotransferase 2

1

1

High-throughput

0.536

High

345004

ITLN2
Intelectin-2

1

1

High-throughput

0.536

High

345013

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

3

High-throughput

0.536

High

345018

GREM2
Gremlin-2

1

1

High-throughput

0.536

High

345030

NXT1
NTF2-related export protein 1

1

1

High-throughput

0.536

High

344978

C1D
Nuclear nucleic acid-binding protein C1D

1

0

High-throughput

0.513

High

345014

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

0

High-throughput

0.513

High

168484

SCAM2
Secretory carrier-associated membrane protein 2

1

2

High-throughput

0.489

High

267604

TADA3
Transcriptional adapter 3

1

1

High-throughput

0.489

High

278709

DNJC8
DnaJ homolog subfamily C member 8

1

1

High-throughput

0.489

High

344924

HBAT
Hemoglobin subunit theta-1

1

6

High-throughput

0.489

High

344962

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

3

High-throughput

0.489

High

344972

RING1
E3 ubiquitin-protein ligase RING1

1

1

High-throughput

0.489

High

344986

AKND1
Protein AKNAD1

1

2

High-throughput

0.489

High

344989

HBM
Hemoglobin subunit mu

1

6

High-throughput

0.489

High

344994

APLF
Aprataxin and PNK-like factor

1

1

High-throughput

0.489

High

344996

NKAP
NF-kappa-B-activating protein

1

2

High-throughput

0.489

High

344998

CJ053
UPF0728 protein C10orf53

1

1

High-throughput

0.489

High

345003

RN141
RING finger protein 141

1

1

High-throughput

0.489

High

345005

CRGN
Gamma-crystallin N

1

2

High-throughput

0.489

High

345008

SNX27
Sorting nexin-27

1

2

High-throughput

0.489

High

345012

CML1
Chemerin-like receptor 1

1

4

High-throughput

0.489

High

345023

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

4

High-throughput

0.489

High

345031

COR1C
Coronin-1C

1

2

High-throughput

0.489

High

175735

HMGB3
High mobility group protein B3

1

1

Small-scale

0.479

High

344776

TIMP1
Metalloproteinase inhibitor 1

1

2

Small-scale

0.479

High

344918

A4
Amyloid-beta precursor protein

1

5

Small-scale

0.479

High

344921

SAP
Prosaposin

1

1

Small-scale

0.479

High

344928

ANXA3
Annexin A3

1

1

Small-scale

0.479

High

344930

PDIA4
Protein disulfide-isomerase A4

1

2

Small-scale

0.479

High

344933

TIMP2
Metalloproteinase inhibitor 2

1

2

Small-scale

0.479

High

344937

FBLN1
Fibulin-1

1

6

Small-scale

0.479

High

344941

PCSK6
Proprotein convertase subtilisin/kexin type 6

1

2

Small-scale

0.479

High

344958

PSA
Puromycin-sensitive aminopeptidase

1

1

Small-scale

0.479

High

344966

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

4

Small-scale

0.479

High

344973

FOXO1
Forkhead box protein O1

1

1

High-throughput

0.479

High

344976

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

5

Small-scale

0.479

High

344977

CUL4A
Cullin-4A

1

2

High-throughput

0.479

High

344995

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

3

Small-scale

0.479

High

171568

PFD6
Prefoldin subunit 6

1

0

Small-scale

0.458

High

239013

CTND1
Catenin delta-1

1

0

Small-scale

0.458

High

259997

TBCA
Tubulin-specific chaperone A

1

0

Small-scale

0.458

High

344913

TFR1
Transferrin receptor protein 1

1

0

Small-scale

0.458

High

344915

SMR3B
Submaxillary gland androgen-regulated protein 3B

1

0

High-throughput

0.458

High

344917

TYSY
Thymidylate synthase

1

0

Small-scale

0.458

High

344931

CD59
CD59 glycoprotein

1

0

Small-scale

0.458

High

344935

GSTM3
Glutathione S-transferase Mu 3

1

0

Small-scale

0.458

High

344940

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

Small-scale

0.458

High

344942

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

1

0

Small-scale

0.458

High

344943

PURA2
Adenylosuccinate synthetase isozyme 2

1

0

Small-scale

0.458

High

344948

TALDO
Transaldolase

1

0

Small-scale

0.458

High

344949

MDHC
Malate dehydrogenase, cytoplasmic

1

0

Small-scale

0.458

High

344950

ACTY
Beta-centractin

1

0

Small-scale

0.458

High

344957

IF5
Eukaryotic translation initiation factor 5

1

0

Small-scale

0.458

High

344961

ARP2
Actin-related protein 2

1

0

Small-scale

0.458

High

344968

HMCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

1

0

Small-scale

0.458

High

344988

KPRP
Keratinocyte proline-rich protein

1

0

Small-scale

0.458

High

345011

DNJC7
DnaJ homolog subfamily C member 7

1

0

Small-scale

0.458

High

345015

SH3L3
SH3 domain-binding glutamic acid-rich-like protein 3

1

0

Small-scale

0.458

High

344916

SODM
Superoxide dismutase [Mn], mitochondrial

1

1

High-throughput

0.437

High

344919

INSR
Insulin receptor

1

6

Small-scale

0.437

High

344934

ITB5
Integrin beta-5

1

3

Small-scale

0.437

High

344939

FKBP2
Peptidyl-prolyl cis-trans isomerase FKBP2

1

4

Small-scale

0.437

High

344947

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

1

Small-scale

0.437

High

344971

UPAR
Urokinase plasminogen activator surface receptor

1

2

Small-scale

0.437

High

344981

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.437

High

345016

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

1

Small-scale

0.437

High

345029

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

5

Small-scale

0.437

High

344969

TAGL
Transgelin

1

0

High-throughput

0.426

High

344992

CPLX4
Complexin-4

2

0

High-throughput

0.328

High

344974

ASPH
Aspartyl/asparaginyl beta-hydroxylase

2

0

High-throughput

0.316

High

345032

IR3IP
Immediate early response 3-interacting protein 1

2

0

High-throughput

0.316

High

243770

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.279

Low

344925

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.279

Low

344952

OMP
Olfactory marker protein

1

0

High-throughput

0.279

Low

344959

PIGP
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

1

0

High-throughput

0.279

Low

344983

INF2
Inverted formin-2

1

0

High-throughput

0.279

Low

344985

ATAT
Alpha-tubulin N-acetyltransferase 1

1

0

High-throughput

0.279

Low

344991

FBX42
F-box only protein 42

1

0

High-throughput

0.279

Low

345017

VIAAT
Vesicular inhibitory amino acid transporter

1

0

High-throughput

0.279

Low

67691

SYC1L
Synaptonemal complex central element protein 1-like

1

0

High-throughput

0.251

Low

174033

SPTC1
Serine palmitoyltransferase 1

1

0

Small-scale

0.249

Low

344923

4F2
Amino acid transporter heavy chain SLC3A2

1

0

Small-scale

0.249

Low

344927

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

Small-scale

0.249

Low

344929

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

Small-scale

0.249

Low

344932

CATE
Cathepsin E

1

0

Small-scale

0.249

Low

344936

VDAC1
Voltage-dependent anion-selective channel protein 1

1

0

Small-scale

0.249

Low

344938

TCEA1
Transcription elongation factor A protein 1

1

0

Small-scale

0.249

Low

344945

PUR9
Bifunctional purine biosynthesis protein ATIC

1

0

Small-scale

0.249

Low

344946

RFA3
Replication protein A 14 kDa subunit

1

0

Small-scale

0.249

Low

344953

RM19
Large ribosomal subunit protein bL19m

1

0

Small-scale

0.249

Low

344954

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

Small-scale

0.249

Low

344955

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

Small-scale

0.249

Low

344965

SERF2
Small EDRK-rich factor 2

1

0

Small-scale

0.249

Low

344970

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

0

Small-scale

0.249

Low

344980

SPCS2
Signal peptidase complex subunit 2

1

0

Small-scale

0.249

Low

344987

CAF17
Putative transferase CAF17, mitochondrial

1

0

Small-scale

0.249

Low

345007

OTUB1
Ubiquitin thioesterase OTUB1

1

0

Small-scale

0.249

Low

345009

ATAD5
ATPase family AAA domain-containing protein 5

1

0

High-throughput

0.249

Low

345022

ABCF3
ATP-binding cassette sub-family F member 3

1

0

Small-scale

0.249

Low

345024

TECR
Very-long-chain enoyl-CoA reductase

1

0

Small-scale

0.249

Low

345025

MYOF
Myoferlin

1

0

Small-scale

0.249

Low

345027

TES
Testin

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024