Protein: OTUD3
OTU domain-containing protein 3 (EC 3.4.19.12)

Gene: OTUD3
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q5T2D3

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475884

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

4

12

Small-scale

0.888

High

1132813

OTUD3
OTU domain-containing protein 3

1

7

Small-scale

0.724

High

890697

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

3

Small-scale

0.646

High

966566

OTUD4
OTU domain-containing protein 4

1

7

Small-scale

0.618

High

1132822

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.618

High

1132821

DHB14
17-beta-hydroxysteroid dehydrogenase 14

2

0

High-throughput

0.580

High

1132816

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.564

High

386881

P53
Cellular tumor antigen p53

1

2

Small-scale

0.561

High

502191

BIP
Endoplasmic reticulum chaperone BiP

1

2

Small-scale

0.561

High

975436

PPARD
Peroxisome proliferator-activated receptor delta

1

4

Small-scale

0.561

High

816816

IREB2
Iron-responsive element-binding protein 2

1

0

Small-scale

0.537

High

1132823

CHIP
E3 ubiquitin-protein ligase CHIP

1

0

Small-scale

0.537

High

67804

GNAT3
Guanine nucleotide-binding protein G(t) subunit alpha-3

1

2

High-throughput

0.536

High

670465

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

2

High-throughput

0.536

High

921600

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.536

High

1053398

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

2

High-throughput

0.536

High

1056362

PLSI
Plastin-1

1

1

High-throughput

0.536

High

1132815

MIB1
E3 ubiquitin-protein ligase MIB1

1

1

High-throughput

0.536

High

1132818

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

1

High-throughput

0.536

High

274101

XRP2
Protein XRP2

1

0

High-throughput

0.513

High

349382

RASH
GTPase HRas

1

0

High-throughput

0.513

High

885550

MLF1
Myeloid leukemia factor 1

1

0

High-throughput

0.513

High

1055913

ZN268
Zinc finger protein 268

1

0

High-throughput

0.513

High

1132814

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.513

High

1132820

ITFG2
KICSTOR complex protein ITFG2

1

0

High-throughput

0.513

High

175971

FOXN1
Forkhead box protein N1

1

1

Small-scale

0.501

High

567799

HXB8
Homeobox protein Hox-B8

1

1

Small-scale

0.501

High

727533

HNF1B
Hepatocyte nuclear factor 1-beta

1

1

Small-scale

0.501

High

311442

SIX3
Homeobox protein SIX3

1

0

Small-scale

0.480

High

932526

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

0

Small-scale

0.480

High

1132817

BHE22
Class E basic helix-loop-helix protein 22

1

0

Small-scale

0.480

High

1132824

FOXA2
Hepatocyte nuclear factor 3-beta

1

0

Small-scale

0.480

High

151814

IRS4
Insulin receptor substrate 4

1

1

Small-scale

0.479

High

160611

AURKA
Aurora kinase A

1

11

Small-scale

0.479

High

296048

MTA2
Metastasis-associated protein MTA2

1

2

Small-scale

0.479

High

582331

NUCL
Nucleolin

1

4

Small-scale

0.479

High

644270

TTP
mRNA decay activator protein ZFP36

1

4

Small-scale

0.479

High

931208

YBOX1
Y-box-binding protein 1

1

4

Small-scale

0.479

High

994202

DHX9
ATP-dependent RNA helicase A

1

4

Small-scale

0.479

High

1023178

FLII
Protein flightless-1 homolog

1

2

Small-scale

0.479

High

1028687

SRSF5
Serine/arginine-rich splicing factor 5

1

6

Small-scale

0.479

High

1052680

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

10

Small-scale

0.479

High

1132819

KAT6A
Histone acetyltransferase KAT6A

1

2

Small-scale

0.479

High

211593

ACTN4
Alpha-actinin-4

1

0

Small-scale

0.458

High

724863

MYH9
Myosin-9

1

0

Small-scale

0.458

High

837694

GBG10

1

0

High-throughput

0.279

Low

1132825

KPTN
KICSTOR complex protein kaptin

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024