Protein: DPOA2
DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit)

Gene: DPOA2, POLA2
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q14181

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005658 - alpha DNA polymerase:primase complex
GO:0005829 - cytosol
GO:0006260 - DNA replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

456118

DPOLA
DNA polymerase alpha catalytic subunit

2

10

Small-scale

0.768

High

1029226

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.656

High

830127

PRI1
DNA primase small subunit

2

3

High-throughput

0.628

High

181322

ARPC5
Actin-related protein 2/3 complex subunit 5

2

0

High-throughput

0.602

High

666907

TKT
Transketolase

2

0

High-throughput

0.602

High

925275

RAC1
Ras-related C3 botulinum toxin substrate 1

2

0

High-throughput

0.602

High

1050454

STN1
CST complex subunit STN1

2

0

High-throughput

0.602

High

1050423

EZH2
Histone-lysine N-methyltransferase EZH2

2

0

High-throughput

0.588

High

227430

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

124510

TULP2
Tubby-related protein 2

2

1

High-throughput

0.574

High

1050439

SNX21
Sorting nexin-21

2

1

High-throughput

0.574

High

1050450

LRC27
Leucine-rich repeat-containing protein 27

2

1

High-throughput

0.574

High

455428

PARP1
Poly [ADP-ribose] polymerase 1

1

2

Small-scale

0.561

High

943830

RAE1L
mRNA export factor RAE1

2

0

High-throughput

0.559

High

814948

LEG7
Galectin-7

2

1

High-throughput

0.558

High

878308

NH2L1
NHP2-like protein 1

1

2

High-throughput

0.541

High

1050422

SETB1
Histone-lysine N-methyltransferase SETDB1

1

1

High-throughput

0.541

High

272925

RFPL2
Ret finger protein-like 2

1

1

High-throughput

0.536

High

708640

MCM5
DNA replication licensing factor MCM5

1

6

High-throughput

0.536

High

996666

SSRP1
FACT complex subunit SSRP1

1

1

High-throughput

0.536

High

1050449

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.536

High

1050432

ULK2
Serine/threonine-protein kinase ULK2

1

0

High-throughput

0.518

High

1050433

STK40
Serine/threonine-protein kinase 40

1

0

High-throughput

0.518

High

1050434

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.518

High

1050445

KLF6
Krueppel-like factor 6

1

0

High-throughput

0.518

High

1050452

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.518

High

1050456

XPP1
Xaa-Pro aminopeptidase 1

1

0

High-throughput

0.518

High

684712

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.515

High

427888

CAN1
Calpain-1 catalytic subunit

1

0

High-throughput

0.513

High

590915

BTF3
Transcription factor BTF3

1

0

High-throughput

0.513

High

1050448

DHRS6
Dehydrogenase/reductase SDR family member 6

1

0

High-throughput

0.513

High

394705

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

830170

PRI2
DNA primase large subunit

1

2

Small-scale

0.501

High

1050451

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.494

High

1050455

AKTIP
AKT-interacting protein

1

1

High-throughput

0.494

High

263625

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.493

High

829377

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

871565

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.493

High

877034

CASP6
Caspase-6

1

0

High-throughput

0.493

High

919074

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.493

High

1050463

SHLB1
Endophilin-B1

1

0

High-throughput

0.493

High

1050436

SSH3
Protein phosphatase Slingshot homolog 3

1

1

High-throughput

0.489

High

611439

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

0

High-throughput

0.486

High

1050430

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.486

High

1050459

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.486

High

1050435

HELB
DNA helicase B

1

0

Small-scale

0.480

High

552704

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

651181

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

826272

CDK8
Cyclin-dependent kinase 8

1

1

High-throughput

0.479

High

918355

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

1041553

CUL3
Cullin-3

1

2

High-throughput

0.479

High

1042973

CUL4A
Cullin-4A

1

2

High-throughput

0.479

High

1043349

CUL4B
Cullin-4B

1

2

High-throughput

0.479

High

1050429

TAXB1
Tax1-binding protein 1

1

1

High-throughput

0.479

High

880922

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.460

High

162735

XPO1
Exportin-1

1

0

High-throughput

0.458

High

244425

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

569717

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

622584

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.458

High

720442

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

932149

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

952326

H33
Histone H3.3

1

0

High-throughput

0.458

High

967868

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1050424

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1050442

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1050444

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1050457

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1050458

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1050460

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1050461

HERC5
E3 ISG15--protein ligase HERC5

1

0

Small-scale

0.458

High

1050428

RBM23
Probable RNA-binding protein 23

1

3

High-throughput

0.439

High

1050447

HGH1
Protein HGH1 homolog

1

1

High-throughput

0.439

High

1032231

CENPR
Centromere protein R

1

0

High-throughput

0.438

High

1050426

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1050427

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1050453

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

497004

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

1050425

Q6IA98
RNPC4 protein

1

3

High-throughput

0.417

High

1050440

Q96BK8
Protein HGH1 homolog

1

1

High-throughput

0.417

High

67757

ZBBX
Zinc finger B-box domain-containing protein 1

2

0

High-throughput

0.328

High

1050437

LIPH
Lipase member H

2

0

High-throughput

0.328

High

562472

CBPE
Carboxypeptidase E

1

0

High-throughput

0.282

High

572511

IBP3
Insulin-like growth factor-binding protein 3

1

0

High-throughput

0.282

High

609285

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.282

High

674663

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.282

High

735939

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.282

High

1049407

DHX34
Probable ATP-dependent RNA helicase DHX34

1

0

High-throughput

0.282

High

1050431

F219A
Protein FAM219A

1

0

High-throughput

0.282

High

1050441

CREL1
Protein disulfide isomerase CRELD1

1

0

High-throughput

0.282

High

1050464

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

0

High-throughput

0.279

Low

311077

MPZL1
Myelin protein zero-like protein 1

1

0

High-throughput

0.279

Low

795751

MAGA3
Melanoma-associated antigen 3

1

0

High-throughput

0.279

Low

975652

LMNB2
Lamin-B2

1

0

High-throughput

0.279

Low

1050443

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.279

Low

1050446

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.279

Low

1050462

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.279

Low

265520

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.268

Low

527451

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

1012396

Q0VDC6
peptidylprolyl isomerase

1

0

High-throughput

0.268

Low

1050438

SFRP3
Secreted frizzled-related protein 3

1

0

High-throughput

0.265

Low

1050465

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.265

Low

282899

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024