Protein: KCTD3
BTB/POZ domain-containing protein KCTD3 (Renal carcinoma antigen NY-REN-45)

Gene: KCTD3
Organism: Homo sapiens
Interactions: 155
UniProt ID: Q9Y597

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0051260 - protein homooligomerization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1174585

KCTD1
BTB/POZ domain-containing protein KCTD1

2

17

High-throughput

0.811

High

1252650

SHKB1
SH3KBP1-binding protein 1

2

18

High-throughput

0.811

High

1302211

KCD15
BTB/POZ domain-containing protein KCTD15

2

18

High-throughput

0.811

High

1042934

CUL3
Cullin-3

6

20

Small-scale

0.732

High

640292

PTN3
Tyrosine-protein phosphatase non-receptor type 3

4

5

High-throughput

0.697

High

1297995

KCTD7
BTB/POZ domain-containing protein KCTD7

1

19

High-throughput

0.691

High

1328947

EPN3
Epsin-3

3

5

High-throughput

0.667

High

1317967

ASPC1
Tether containing UBX domain for GLUT4

2

2

High-throughput

0.628

High

1132930

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

2

20

High-throughput

0.611

High

603271

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

3

1

High-throughput

0.609

High

1044745

FHL3
Four and a half LIM domains protein 3

3

2

High-throughput

0.609

High

1310836

WDR83
WD repeat domain-containing protein 83

3

6

High-throughput

0.609

High

1377912

ARI1
E3 ubiquitin-protein ligase ARIH1

3

7

High-throughput

0.609

High

1261755

TPC14
Trafficking protein particle complex subunit 14

2

0

High-throughput

0.602

High

872325

RD23B
UV excision repair protein RAD23 homolog B

2

5

High-throughput

0.574

High

896280

UBC12
NEDD8-conjugating enzyme Ubc12

2

8

High-throughput

0.574

High

370812

ESR1
Estrogen receptor

2

9

High-throughput

0.571

High

636534

DNJB2
DnaJ homolog subfamily B member 2

2

6

High-throughput

0.558

High

1296975

SNX27
Sorting nexin-27

2

20

High-throughput

0.558

High

809498

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

2

High-throughput

0.536

High

871845

HSP72
Heat shock-related 70 kDa protein 2

1

10

High-throughput

0.536

High

1075479

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

20

High-throughput

0.536

High

1334867

PKHA5
Pleckstrin homology domain-containing family A member 5

2

9

Small-scale

0.533

High

1153476

PKHA7
Pleckstrin homology domain-containing family A member 7

2

10

High-throughput

0.521

High

827299

ARRB1
Beta-arrestin-1

1

0

High-throughput

0.513

High

388828

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.494

High

153961

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

20

High-throughput

0.489

High

243683

DNJA2
DnaJ homolog subfamily A member 2

1

8

High-throughput

0.489

High

324143

BAG2
BAG family molecular chaperone regulator 2

1

3

High-throughput

0.489

High

718366

BMI1
Polycomb complex protein BMI-1

1

6

High-throughput

0.489

High

921492

RBX1
E3 ubiquitin-protein ligase RBX1

1

6

High-throughput

0.489

High

1079644

NEDD8
NEDD8

1

3

High-throughput

0.489

High

1136035

RNH2B
Ribonuclease H2 subunit B

1

1

High-throughput

0.489

High

1161502

DCNL2
DCN1-like protein 2

1

4

High-throughput

0.489

High

1232320

MTURN
Maturin

1

4

High-throughput

0.489

High

1233290

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.489

High

1260464

FBLI1
Filamin-binding LIM protein 1

1

6

High-throughput

0.489

High

1272737

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.489

High

1283480

SPSB4
SPRY domain-containing SOCS box protein 4

1

8

High-throughput

0.489

High

1292417

DCNL1
DCN1-like protein 1

1

4

High-throughput

0.489

High

1306185

NPAS1
Neuronal PAS domain-containing protein 1

1

1

High-throughput

0.489

High

1332821

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.489

High

166639

DCLK1
Serine/threonine-protein kinase DCLK1

1

3

High-throughput

0.479

High

196537

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

1

High-throughput

0.479

High

598553

NF1
Neurofibromin

1

2

High-throughput

0.479

High

608208

FGFR4
Fibroblast growth factor receptor 4

1

4

High-throughput

0.479

High

876551

AFAD
Afadin

1

13

High-throughput

0.479

High

882663

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

6

High-throughput

0.479

High

894625

CDC42
Cell division control protein 42 homolog

1

7

High-throughput

0.479

High

906217

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

3

High-throughput

0.479

High

960432

CDK16
Cyclin-dependent kinase 16

1

4

High-throughput

0.479

High

1020242

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

6

High-throughput

0.479

High

1022479

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

3

High-throughput

0.479

High

1057215

MELK
Maternal embryonic leucine zipper kinase

1

2

High-throughput

0.479

High

1078552

NCOA1
Nuclear receptor coactivator 1

1

2

Small-scale

0.479

High

1139658

DEN4C
DENN domain-containing protein 4C

1

2

High-throughput

0.479

High

1164934

CRTC1
CREB-regulated transcription coactivator 1

1

4

High-throughput

0.479

High

1197858

PHLB2
Pleckstrin homology-like domain family B member 2

1

4

High-throughput

0.479

High

1203953

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

3

High-throughput

0.479

High

1285234

SH3K1
SH3 domain-containing kinase-binding protein 1

1

8

High-throughput

0.479

High

1300703

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

20

High-throughput

0.479

High

1316850

ACE2
Angiotensin-converting enzyme 2

1

1

Small-scale

0.479

High

1318040

OSBL6
Oxysterol-binding protein-related protein 6

1

1

High-throughput

0.479

High

1331240

OSBL3
Oxysterol-binding protein-related protein 3

1

1

High-throughput

0.479

High

1331736

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.479

High

1350032

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

3

High-throughput

0.479

High

1350458

CING
Cingulin

1

1

High-throughput

0.479

High

1355292

LIMA1
LIM domain and actin-binding protein 1

1

3

High-throughput

0.479

High

1356324

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

2

High-throughput

0.479

High

1357868

BAIP2
BAR/IMD domain-containing adapter protein 2

1

1

High-throughput

0.479

High

1357880

GAB2
GRB2-associated-binding protein 2

1

5

High-throughput

0.479

High

1185023

CSN6
COP9 signalosome complex subunit 6

1

4

High-throughput

0.470

High

1273591

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

8

High-throughput

0.470

High

321445

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

1

High-throughput

0.464

High

253437

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

0

High-throughput

0.458

High

1308740

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

0

High-throughput

0.458

High

1345067

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

0

High-throughput

0.458

High

163522

XPO1
Exportin-1

1

10

High-throughput

0.437

High

216995

KIF1C
Kinesin-like protein KIF1C

1

10

High-throughput

0.437

High

230942

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

3

High-throughput

0.437

High

231779

KIF1B
Kinesin-like protein KIF1B

1

10

High-throughput

0.437

High

264448

GGYF1
GRB10-interacting GYF protein 1

1

2

High-throughput

0.437

High

554159

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

652717

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

673310

WEE1
Wee1-like protein kinase

1

3

High-throughput

0.437

High

673541

MPIP2
M-phase inducer phosphatase 2

1

3

High-throughput

0.437

High

673646

MPIP3
M-phase inducer phosphatase 3

1

3

High-throughput

0.437

High

721883

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

822210

KC1A
Casein kinase I isoform alpha

1

1

High-throughput

0.437

High

880870

HDAC4
Histone deacetylase 4

1

3

High-throughput

0.437

High

997246

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

2

High-throughput

0.437

High

1060658

ZN638
Zinc finger protein 638

1

2

High-throughput

0.437

High

1076945

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

5

High-throughput

0.437

High

1120163

CRTC2
CREB-regulated transcription coactivator 2

1

3

High-throughput

0.437

High

1136568

SPD2A
SH3 and PX domain-containing protein 2A

1

7

High-throughput

0.437

High

1149016

AN34A
Ankyrin repeat domain-containing protein 34A

1

9

High-throughput

0.437

High

1162725

LARP1
La-related protein 1

1

1

High-throughput

0.437

High

1164925

CRTC3
CREB-regulated transcription coactivator 3

1

3

High-throughput

0.437

High

1168023

GGYF2
GRB10-interacting GYF protein 2

1

5

High-throughput

0.437

High

1172948

FGD6
FYVE, RhoGEF and PH domain-containing protein 6

1

4

High-throughput

0.437

High

1173169

SYDE1
Rho GTPase-activating protein SYDE1

1

4

High-throughput

0.437

High

1185279

RFIP2
Rab11 family-interacting protein 2

1

7

High-throughput

0.437

High

1189743

MYCPP
C-myc promoter-binding protein

1

2

High-throughput

0.437

High

1198517

TBCD1
TBC1 domain family member 1

1

1

High-throughput

0.437

High

1218008

KSR1
Kinase suppressor of Ras 1

1

1

High-throughput

0.437

High

1218203

CEP97
Centrosomal protein of 97 kDa

1

11

Small-scale

0.437

High

1224201

DCP1B
mRNA-decapping enzyme 1B

1

3

High-throughput

0.437

High

1230081

RPTOR
Regulatory-associated protein of mTOR

1

4

High-throughput

0.437

High

1232346

MILK1
MICAL-like protein 1

1

9

High-throughput

0.437

High

1243707

NAV1
Neuron navigator 1

1

1

High-throughput

0.437

High

1253350

F110B
Protein FAM110B

1

1

High-throughput

0.437

High

1256273

DEN1A
DENN domain-containing protein 1A

1

2

High-throughput

0.437

High

1256291

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

6

High-throughput

0.437

High

1260207

HDAC7
Histone deacetylase 7

1

3

High-throughput

0.437

High

1260805

DEP1B
DEP domain-containing protein 1B

1

1

High-throughput

0.437

High

1262636

LMO7
LIM domain only protein 7

1

2

High-throughput

0.437

High

1263484

SRS12
Serine/arginine-rich splicing factor 12

1

1

High-throughput

0.437

High

1270030

ESR2
Estrogen receptor beta

1

8

High-throughput

0.437

High

1303031

MMS19
MMS19 nucleotide excision repair protein homolog

1

1

High-throughput

0.437

High

1309190

F110A
Protein FAM110A

1

1

High-throughput

0.437

High

1315560

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

6

High-throughput

0.437

High

1335971

TANC2
Protein TANC2

1

4

High-throughput

0.437

High

1342898

DCP1A
mRNA-decapping enzyme 1A

1

2

High-throughput

0.437

High

1343641

KI13B
Kinesin-like protein KIF13B

1

9

High-throughput

0.437

High

1355997

NGAP
Ras GTPase-activating protein nGAP

1

2

High-throughput

0.437

High

1357707

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

2

High-throughput

0.437

High

1357906

HDAC5
Histone deacetylase 5

1

3

High-throughput

0.437

High

1377716

STA13
StAR-related lipid transfer protein 13

1

1

High-throughput

0.437

High

67925

PDZ1P
Putative PDZ domain-containing protein PDZK1P1

1

20

High-throughput

0.407

High

1131905

CE170
Centrosomal protein of 170 kDa

1

2

High-throughput

0.407

High

1301425

NUDC1
NudC domain-containing protein 1

1

1

High-throughput

0.407

High

1233658

CARME
Carnosine N-methyltransferase

3

0

High-throughput

0.347

High

1197965

TPC6B
Trafficking protein particle complex subunit 6B

2

0

High-throughput

0.328

High

1300054

TPPC9
Trafficking protein particle complex subunit 9

2

0

High-throughput

0.328

High

154273

CHK1
Serine/threonine-protein kinase Chk1

1

0

High-throughput

0.249

Low

237360

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.249

Low

316293

NADK
NAD kinase

1

0

High-throughput

0.249

Low

331124

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.249

Low

1136496

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

0

High-throughput

0.249

Low

1148903

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1156250

REEP3
Receptor expression-enhancing protein 3

1

0

High-throughput

0.249

Low

1160016

KLC3
Kinesin light chain 3

1

0

High-throughput

0.249

Low

1284910

DACT3
Dapper homolog 3

1

0

High-throughput

0.249

Low

1291014

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.249

Low

1291475

SCRN2
Secernin-2

1

0

High-throughput

0.249

Low

1301731

TESK2
Dual specificity testis-specific protein kinase 2

1

0

High-throughput

0.249

Low

1309752

LPIN3
Phosphatidate phosphatase LPIN3

1

0

High-throughput

0.249

Low

1311616

RTKN
Rhotekin

1

0

High-throughput

0.249

Low

1317678

PANK2
Pantothenate kinase 2, mitochondrial

1

0

High-throughput

0.249

Low

1327094

MFR1L
Mitochondrial fission regulator 1-like

1

0

High-throughput

0.249

Low

1347944

CWC25
Pre-mRNA-splicing factor CWC25 homolog

1

0

High-throughput

0.249

Low

1348463

FA53C
Protein FAM53C

1

0

High-throughput

0.249

Low

1356900

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.249

Low

1356978

PPM1H
Protein phosphatase 1H

1

0

High-throughput

0.249

Low

1377714

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024