HitPredict

Interactor 1: FOXO6 (A8MYZ6)
Forkhead box protein O6
Gene: FOXO6

Interactor 2: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 492 Hs			1 246
+	Hs
		68646 FOXO6_HUMAN (1-492): 5.19e-100: 311: 100.00		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		46294 A0A1X9RU27_HUMAN (1-492): 9.85e-81: 263: 74.06		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		46295 A0A1X9RU27_HUMAN (1-492): 9.85e-81: 263: 74.06		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Hs
		68644 FOXO6_HUMAN (1-492): 5.19e-100: 311: 100.00		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		68643 FOXO6_HUMAN (1-492): 5.19e-100: 311: 100.00		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		909442 FOXO4_HUMAN (10-469): 8.18e-57: 198: 37.40		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Dm
		955013 FOXO_DROME (8-467): 1.33e-56: 200: 30.77		1433E_DROME (1-243): 7.96e-141: 396: 63.37
+	Hs
		904445 FOXO4_HUMAN (10-469): 8.18e-57: 198: 37.40		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		958163 FOXO4_HUMAN (10-469): 8.18e-57: 198: 37.40		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Hs
		46293 A0A1X9RU27_HUMAN (1-492): 9.85e-81: 263: 74.06		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		46292 A0A1X9RU27_HUMAN (1-492): 9.85e-81: 263: 74.06		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Ce
		184241 FOXO_CAEEL (33-469): 2.55e-56: 198: 27.33		14332_CAEEL (4-241): 1.43e-108: 314: 76.05
+	Dm
		664627 FOXO_DROME (8-467): 1.33e-56: 200: 30.77		1433Z_DROME (3-242): 8.23e-108: 312: 73.33
+	Hs
		926923 FOXO4_HUMAN (10-469): 8.18e-57: 198: 37.40		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		683267 FOXO4_HUMAN (10-469): 8.18e-57: 198: 37.40		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Ce
		184222 FOXO_CAEEL (33-469): 2.55e-56: 198: 27.33		14331_CAEEL (5-246): 3.56e-101: 296: 74.49
+	Hs
		683226 FOXA1_HUMAN (32-406): 1.58e-48: 175: 23.91		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		683300 FOXO1_HUMAN (31-492): 1.03e-46: 173: 32.21		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		683962 FOXO4_HUMAN (10-469): 8.18e-57: 198: 37.40		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20
+	Hs
		646840 FOXO1_HUMAN (31-492): 1.03e-46: 173: 32.21		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43