Protein: S4A7
Sodium bicarbonate cotransporter 3 (Electroneutral Na/HCO(3) cotransporter) (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7)

Gene: S4A7, SLC4A7
Organism: Homo sapiens
Interactions: 177
UniProt ID: Q9Y6M7

Gene Ontology (top 5):
GO:0005452 - solute:inorganic anion antiporter activity
GO:0005886 - plasma membrane
GO:0006164 - purine nucleotide biosynthetic process
GO:0006221 - pyrimidine nucleotide biosynthetic process
GO:0008509 - monoatomic anion transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1103587

S4A8
Electroneutral sodium bicarbonate exchanger 1

2

5

High-throughput

0.811

High

683859

1433B
14-3-3 protein beta/alpha

6

7

High-throughput

0.732

High

1377080

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

1

High-throughput

0.691

High

905323

1433G
14-3-3 protein gamma

4

7

High-throughput

0.691

High

350745

RASK
GTPase KRas

4

12

High-throughput

0.676

High

121238

LEG8
Galectin-8

3

10

High-throughput

0.667

High

572492

LEG3
Galectin-3

3

10

High-throughput

0.667

High

1287775

RHES
GTP-binding protein Rhes

3

3

High-throughput

0.667

High

647428

1433T
14-3-3 protein theta

3

7

High-throughput

0.650

High

982671

1433F
14-3-3 protein eta

3

7

High-throughput

0.650

High

349042

RASN
GTPase NRas

3

12

High-throughput

0.640

High

349774

RASH
GTPase HRas

3

8

High-throughput

0.640

High

1236053

TEX29
Testis-expressed protein 29

3

0

High-throughput

0.638

High

1349015

GDE1
Glycerophosphodiester phosphodiesterase 1

3

0

High-throughput

0.638

High

119587

LEG9
Galectin-9

4

10

High-throughput

0.633

High

560368

EPB42
Protein 4.2

2

1

High-throughput

0.628

High

591260

ACM3
Muscarinic acetylcholine receptor M3

2

2

High-throughput

0.628

High

910215

1433E
14-3-3 protein epsilon

2

1

High-throughput

0.611

High

1132932

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

2

10

High-throughput

0.611

High

1150408

LEG9C
Galectin-9C

3

10

High-throughput

0.609

High

1307321

EGFL8
Epidermal growth factor-like protein 8

3

2

High-throughput

0.609

High

1223703

IZUM1
Izumo sperm-egg fusion protein 1

2

0

High-throughput

0.602

High

1244910

GP156
Probable G-protein coupled receptor 156

2

0

High-throughput

0.602

High

927718

1433Z
14-3-3 protein zeta/delta

3

7

High-throughput

0.599

High

793550

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.586

High

940617

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.586

High

385820

NTRK1
High affinity nerve growth factor receptor

2

4

High-throughput

0.584

High

507347

LAMP1
Lysosome-associated membrane glycoprotein 1

2

3

High-throughput

0.584

High

890547

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.584

High

913223

ARF6
ADP-ribosylation factor 6

2

1

High-throughput

0.584

High

916111

RHOB
Rho-related GTP-binding protein RhoB

2

15

High-throughput

0.584

High

370836

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

942406

DLG4
Disks large homolog 4

1

3

Small-scale

0.561

High

1296985

SNX27
Sorting nexin-27

2

7

High-throughput

0.558

High

283073

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

2

High-throughput

0.553

High

121543

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

1

High-throughput

0.536

High

380160

MAS
Proto-oncogene Mas

1

5

High-throughput

0.536

High

507594

PIM1
Serine/threonine-protein kinase pim-1

1

2

High-throughput

0.536

High

591441

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

1

High-throughput

0.536

High

966911

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

2

High-throughput

0.536

High

1075480

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

11

High-throughput

0.536

High

1299288

OPALI
Opalin

1

1

High-throughput

0.536

High

1304406

PLIN2
Perilipin-2

1

1

High-throughput

0.536

High

1329949

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.536

High

1377251

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

1

High-throughput

0.536

High

1234591

SH2D3
SH2 domain-containing protein 3C

2

2

High-throughput

0.521

High

529984

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

Small-scale

0.515

High

548173

KCNE1
Potassium voltage-gated channel subfamily E member 1

1

0

High-throughput

0.513

High

574494

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

798162

KI2L1
Killer cell immunoglobulin-like receptor 2DL1

1

0

High-throughput

0.513

High

806750

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

944011

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

1265981

CLC2B
C-type lectin domain family 2 member B

1

0

High-throughput

0.513

High

1298742

TMM74
Transmembrane protein 74

1

0

High-throughput

0.513

High

825772

MTR1B
Melatonin receptor type 1B

1

1

High-throughput

0.508

High

1378224

USH1C
Harmonin

1

10

Small-scale

0.506

High

153962

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

12

Small-scale

0.501

High

1050101

SCRIB
Protein scribble homolog

1

3

High-throughput

0.501

High

1107991

LEG9B
Galectin-9B

1

10

High-throughput

0.489

High

1377028

CCL26
C-C motif chemokine 26

1

1

High-throughput

0.489

High

120744

RHOD
Rho-related GTP-binding protein RhoD

1

19

High-throughput

0.479

High

169687

BET1
BET1 homolog

1

1

High-throughput

0.479

High

178898

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

206245

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

213087

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

279779

FLOT1
Flotillin-1

1

1

High-throughput

0.479

High

305703

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.479

High

318267

DIRA3
GTP-binding protein Di-Ras3

1

2

High-throughput

0.479

High

390649

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.479

High

391290

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

434110

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.479

High

436601

RHOC
Rho-related GTP-binding protein RhoC

1

12

High-throughput

0.479

High

527923

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

545733

RAC2
Ras-related C3 botulinum toxin substrate 2

1

13

High-throughput

0.479

High

547303

EZRI
Ezrin

1

1

High-throughput

0.479

High

564763

RHOQ
Rho-related GTP-binding protein RhoQ

1

16

High-throughput

0.479

High

567357

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.479

High

591733

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.479

High

592092

RAB4A
Ras-related protein Rab-4A

1

3

High-throughput

0.479

High

592621

RAB5A
Ras-related protein Rab-5A

1

3

High-throughput

0.479

High

600721

EPHA1
Ephrin type-A receptor 1

1

2

High-throughput

0.479

High

654950

CALX
Calnexin

1

3

High-throughput

0.479

High

825618

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

844819

RAB5C
Ras-related protein Rab-5C

1

3

High-throughput

0.479

High

845396

RAB7A
Ras-related protein Rab-7a

1

5

High-throughput

0.479

High

845840

RAB9A
Ras-related protein Rab-9A

1

5

High-throughput

0.479

High

847745

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

852701

RND2
Rho-related GTP-binding protein RhoN

1

17

High-throughput

0.479

High

876554

AFAD
Afadin

1

5

High-throughput

0.479

High

881581

ARL4C
ADP-ribosylation factor-like protein 4C

1

3

High-throughput

0.479

High

892709

RAC3
Ras-related C3 botulinum toxin substrate 3

1

15

High-throughput

0.479

High

894643

CDC42
Cell division control protein 42 homolog

1

17

High-throughput

0.479

High

901109

RHOA
Transforming protein RhoA

1

13

High-throughput

0.479

High

901287

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

925775

RAC1
Ras-related C3 botulinum toxin substrate 1

1

15

High-throughput

0.479

High

951507

RHOG
Rho-related GTP-binding protein RhoG

1

13

High-throughput

0.479

High

975140

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

990763

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.479

High

1017866

STX4
Syntaxin-4

1

3

High-throughput

0.479

High

1070490

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.479

High

1072639

EPHA7
Ephrin type-A receptor 7

1

2

High-throughput

0.479

High

1076840

RHOH
Rho-related GTP-binding protein RhoH

1

15

High-throughput

0.479

High

1081664

NTRK3
NT-3 growth factor receptor

1

4

High-throughput

0.479

High

1083915

NTRK2
BDNF/NT-3 growth factors receptor

1

4

High-throughput

0.479

High

1084266

OCLN
Occludin

1

2

High-throughput

0.479

High

1087647

CAH9
Carbonic anhydrase 9

1

5

High-throughput

0.479

High

1152239

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1153764

STYK1
Tyrosine-protein kinase STYK1

1

2

High-throughput

0.479

High

1183634

RHOU
Rho-related GTP-binding protein RhoU

1

19

High-throughput

0.479

High

1230451

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.479

High

1269268

RND1
Rho-related GTP-binding protein Rho6

1

19

High-throughput

0.479

High

1284202

LRC59
Leucine-rich repeat-containing protein 59

1

2

High-throughput

0.479

High

1296134

DNJC1
DnaJ homolog subfamily C member 1

1

3

High-throughput

0.479

High

1296779

RHOV
Rho-related GTP-binding protein RhoV

1

17

High-throughput

0.479

High

1300825

PANX1
Pannexin-1

1

1

High-throughput

0.479

High

1330464

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.479

High

1331018

RHOJ
Rho-related GTP-binding protein RhoJ

1

16

High-throughput

0.479

High

1333636

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

1335431

RHOF
Rho-related GTP-binding protein RhoF

1

17

High-throughput

0.479

High

1344487

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.479

High

1348633

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

1350603

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

1354635

DNJ5B
DnaJ homolog subfamily C member 5B

1

2

High-throughput

0.479

High

1357952

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.479

High

146067

CLD4
Claudin-4

1

0

Small-scale

0.458

High

233030

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

0

High-throughput

0.458

High

522300

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

568846

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.458

High

670309

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

795354

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

839261

EMD
Emerin

1

0

High-throughput

0.458

High

1064913

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1237054

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

1282688

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.458

High

1303656

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1313123

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1319304

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1330585

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1344199

DDX21
Nucleolar RNA helicase 2

1

0

High-throughput

0.458

High

1349733

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

67927

PDZ1P
Putative PDZ domain-containing protein PDZK1P1

1

9

High-throughput

0.445

High

573993

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

2

High-throughput

0.437

High

684431

1433S
14-3-3 protein sigma

1

7

High-throughput

0.437

High

895342

RAB2A
Ras-related protein Rab-2A

1

3

High-throughput

0.437

High

1024797

TRAF3
TNF receptor-associated factor 3

1

2

Small-scale

0.437

High

1071725

KS6A2
Ribosomal protein S6 kinase alpha-2

1

1

High-throughput

0.437

High

1172493

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1174244

MOB2
MOB kinase activator 2

1

1

High-throughput

0.437

High

1174348

MOB3C
MOB kinase activator 3C

1

1

High-throughput

0.437

High

1240382

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.437

High

1283122

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1328904

DJC25
DnaJ homolog subfamily C member 25

1

1

High-throughput

0.437

High

1329344

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.437

High

1336483

E41LA
Band 4.1-like protein 4A

1

1

High-throughput

0.437

High

398156

ISG15
Ubiquitin-like protein ISG15

1

4

Small-scale

0.407

High

1021213

FOXD4
Forkhead box protein D4

3

0

High-throughput

0.352

High

1089449

ODAPH
Odontogenesis associated phosphoprotein

2

0

High-throughput

0.328

High

1282317

SNX21
Sorting nexin-21

2

0

High-throughput

0.328

High

1317321

KRA45
Keratin-associated protein 4-5

2

0

High-throughput

0.316

High

198078

PHF1
PHD finger protein 1

1

0

High-throughput

0.279

Low

435973

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.279

Low

1311886

PSMG3
Proteasome assembly chaperone 3

1

0

High-throughput

0.279

Low

1356262

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

132651

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

486693

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

914505

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.249

Low

941643

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1016270

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.249

Low

1119692

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1200385

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.249

Low

1203931

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1237358

UBR7
Putative E3 ubiquitin-protein ligase UBR7

1

0

High-throughput

0.249

Low

1299964

FMNL2
Formin-like protein 2

1

0

High-throughput

0.249

Low

1343874

ANLN
Anillin

1

0

High-throughput

0.249

Low

1346230

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1347008

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low

1377222

DJC16
DnaJ homolog subfamily C member 16

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024