Protein: CRNL1
Crooked neck-like protein 1 (Crooked neck homolog) (hCrn)

Gene: CRNL1, CRNKL1
Organism: Homo sapiens
Interactions: 147
UniProt ID: Q9BZJ0

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

327811

SYF2
Pre-mRNA-splicing factor SYF2

3

1

High-throughput

0.861

High

1303717

CDC5L
Cell division cycle 5-like protein

3

13

High-throughput

0.814

High

1318164

PRP19
Pre-mRNA-processing factor 19

4

20

High-throughput

0.699

High

1055473

DHX8
ATP-dependent RNA helicase DHX8

4

18

High-throughput

0.694

High

1251015

SNIP1
Smad nuclear-interacting protein 1

4

3

High-throughput

0.694

High

1318165

PPIE
Peptidyl-prolyl cis-trans isomerase E

4

7

High-throughput

0.694

High

1318170

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

4

2

High-throughput

0.694

High

1039828

SNW1
SNW domain-containing protein 1

1

9

High-throughput

0.691

High

911958

RUXF
Small nuclear ribonucleoprotein F

3

20

High-throughput

0.675

High

453901

RU2A
U2 small nuclear ribonucleoprotein A'

3

12

High-throughput

0.667

High

1197543

RALYL
RNA-binding Raly-like protein

3

20

High-throughput

0.667

High

1201653

ZCH18
Zinc finger CCCH domain-containing protein 18

3

9

High-throughput

0.667

High

1308993

USB1
U6 snRNA phosphodiesterase 1

3

1

High-throughput

0.667

High

1310798

WDR83
WD repeat domain-containing protein 83

3

20

High-throughput

0.667

High

1314499

YJU2
Splicing factor YJU2

3

6

High-throughput

0.667

High

1260019

CCD12
Coiled-coil domain-containing protein 12

2

3

High-throughput

0.644

High

209476

PLRG1
Pleiotropic regulator 1

2

20

High-throughput

0.628

High

441365

RU2B
U2 small nuclear ribonucleoprotein B''

2

20

High-throughput

0.628

High

448809

RU1C
U1 small nuclear ribonucleoprotein C

2

3

High-throughput

0.628

High

539141

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

12

High-throughput

0.628

High

911737

RUXE
Small nuclear ribonucleoprotein E

2

6

High-throughput

0.628

High

928016

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

14

High-throughput

0.628

High

1020325

ELAV2
ELAV-like protein 2

2

11

High-throughput

0.628

High

1318151

PININ
Pinin

2

3

High-throughput

0.628

High

1318159

DJC17
DnaJ homolog subfamily C member 17

2

11

High-throughput

0.628

High

124072

SPT5H
Transcription elongation factor SPT5

2

5

High-throughput

0.611

High

912106

RUXG
Small nuclear ribonucleoprotein G

2

20

High-throughput

0.611

High

1054569

RBM39
RNA-binding protein 39

2

18

High-throughput

0.611

High

1288293

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

2

20

High-throughput

0.611

High

1063606

SUZ12
Polycomb protein SUZ12

2

3

High-throughput

0.601

High

228611

PRKN
E3 ubiquitin-protein ligase parkin

2

18

High-throughput

0.584

High

347832

MYC
Myc proto-oncogene protein

2

16

High-throughput

0.584

High

1159278

PRP8
Pre-mRNA-processing-splicing factor 8

2

11

High-throughput

0.584

High

1172885

NKAP1
Uncharacterized protein NKAPD1

2

1

High-throughput

0.574

High

1273626

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

3

High-throughput

0.574

High

1284566

K1143
Uncharacterized protein KIAA1143

2

2

High-throughput

0.574

High

1310125

LZTS2
Leucine zipper putative tumor suppressor 2

2

10

High-throughput

0.574

High

370376

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

388709

HSPB1
Heat shock protein beta-1

1

3

High-throughput

0.541

High

71227

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

16

High-throughput

0.536

High

181247

NUP42
Nucleoporin NUP42

1

1

High-throughput

0.536

High

241360

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

16

High-throughput

0.536

High

256574

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

1

High-throughput

0.536

High

268853

SF3B1
Splicing factor 3B subunit 1

1

8

High-throughput

0.536

High

278528

SPF27
Pre-mRNA-splicing factor SPF27

1

3

High-throughput

0.536

High

418630

NPM
Nucleophosmin

1

4

High-throughput

0.536

High

432907

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

20

High-throughput

0.536

High

446782

SNRPA
U1 small nuclear ribonucleoprotein A

1

20

High-throughput

0.536

High

508698

TOP1
DNA topoisomerase 1

1

4

High-throughput

0.536

High

534268

YJU2B
Probable splicing factor YJU2B

1

6

High-throughput

0.536

High

595394

LMNB1
Lamin-B1

1

7

High-throughput

0.536

High

739273

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.536

High

757750

IF4A3
Eukaryotic initiation factor 4A-III

1

8

High-throughput

0.536

High

806161

RL5
Large ribosomal subunit protein uL18

1

3

High-throughput

0.536

High

908134

RS16
Small ribosomal subunit protein uS9

1

2

High-throughput

0.536

High

952113

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.536

High

996880

SSRP1
FACT complex subunit SSRP1

1

10

High-throughput

0.536

High

1019626

ILF2
Interleukin enhancer-binding factor 2

1

5

High-throughput

0.536

High

1029079

SRSF6
Serine/arginine-rich splicing factor 6

1

16

High-throughput

0.536

High

1064694

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

15

High-throughput

0.536

High

1070619

RNPS1
RNA-binding protein with serine-rich domain 1

1

20

High-throughput

0.536

High

1074228

SF3A1
Splicing factor 3A subunit 1

1

6

High-throughput

0.536

High

1084398

SRSF7
Serine/arginine-rich splicing factor 7

1

16

High-throughput

0.536

High

1084606

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

14

High-throughput

0.536

High

1092901

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

7

High-throughput

0.536

High

1263527

PSPC1
Paraspeckle component 1

1

16

High-throughput

0.536

High

1264426

CTBL1
Beta-catenin-like protein 1

1

1

High-throughput

0.536

High

1318153

LN28A
Protein lin-28 homolog A

1

7

High-throughput

0.536

High

1318156

DDX21
Nucleolar RNA helicase 2

1

11

High-throughput

0.536

High

1318160

PUF60
Poly(U)-binding-splicing factor PUF60

1

17

High-throughput

0.536

High

1318162

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

6

High-throughput

0.536

High

1318166

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.536

High

1318168

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

1

4

High-throughput

0.536

High

819667

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.518

High

1318158

DISC1
Disrupted in schizophrenia 1 protein

2

2

High-throughput

0.516

High

1270083

PRCC
Proline-rich protein PRCC

1

0

High-throughput

0.513

High

1318169

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

833812

CLK1
Dual specificity protein kinase CLK1

1

9

High-throughput

0.501

High

672728

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.489

High

1252867

ZCH10
Zinc finger CCHC domain-containing protein 10

1

1

High-throughput

0.489

High

122984

MEN1
Menin

1

5

High-throughput

0.479

High

131074

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.479

High

244900

BRD4
Bromodomain-containing protein 4

1

10

High-throughput

0.479

High

268269

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

323100

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

16

High-throughput

0.479

High

360380

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

7

High-throughput

0.479

High

374836

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

11

High-throughput

0.479

High

379835

MYCN
N-myc proto-oncogene protein

1

16

High-throughput

0.479

High

487741

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

553643

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.479

High

570040

CEBPB
CCAAT/enhancer-binding protein beta

1

12

High-throughput

0.479

High

652175

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

685006

STIP1
Stress-induced-phosphoprotein 1

1

13

High-throughput

0.479

High

718171

BMI1
Polycomb complex protein BMI-1

1

13

High-throughput

0.479

High

721371

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

750455

COIL
Coilin

1

5

High-throughput

0.479

High

780058

CCNF
Cyclin-F

1

9

High-throughput

0.479

High

824360

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

7

High-throughput

0.479

High

899563

MGN
Protein mago nashi homolog

1

1

High-throughput

0.479

High

976511

ERCC6
DNA excision repair protein ERCC-6

1

15

Small-scale

0.479

High

1036050

BIRC3
Baculoviral IAP repeat-containing protein 3

1

9

High-throughput

0.479

High

1037884

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

11

High-throughput

0.479

High

1059851

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

11

High-throughput

0.479

High

1064119

TNIP1
TNFAIP3-interacting protein 1

1

12

High-throughput

0.479

High

1080307

EZH2
Histone-lysine N-methyltransferase EZH2

1

13

High-throughput

0.479

High

1085935

IF16
Gamma-interferon-inducible protein 16

1

7

High-throughput

0.479

High

1122726

EAPP
E2F-associated phosphoprotein

1

2

High-throughput

0.479

High

1188825

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

8

High-throughput

0.479

High

1221714

SMC5
Structural maintenance of chromosomes protein 5

1

7

High-throughput

0.479

High

1222558

SLX4
Structure-specific endonuclease subunit SLX4

1

12

High-throughput

0.479

High

1243920

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1256377

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1281842

FBX32
F-box only protein 32

1

2

High-throughput

0.479

High

1283844

FUBP1
Far upstream element-binding protein 1

1

8

High-throughput

0.479

High

1304088

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1306963

ANM1
Protein arginine N-methyltransferase 1

1

6

High-throughput

0.479

High

1315487

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

6

High-throughput

0.479

High

1318155

ANLN
Anillin

1

5

High-throughput

0.479

High

1318157

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

8

High-throughput

0.479

High

1318163

FZR1
Fizzy-related protein homolog

1

20

High-throughput

0.479

High

1318167

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

20

High-throughput

0.479

High

911047

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.458

High

68456

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

20

High-throughput

0.445

High

402450

JUN
Transcription factor Jun

1

9

High-throughput

0.445

High

998178

NCBP1
Nuclear cap-binding protein subunit 1

1

3

High-throughput

0.445

High

1044127

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

High-throughput

0.445

High

1120454

NCBP3
Nuclear cap-binding protein subunit 3

1

2

High-throughput

0.445

High

1124617

ODFP2
Outer dense fiber protein 2

1

2

High-throughput

0.445

High

1318161

DDX41
Probable ATP-dependent RNA helicase DDX41

1

9

High-throughput

0.445

High

149256

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.437

High

256048

OBSL1
Obscurin-like protein 1

1

3

High-throughput

0.437

High

297674

RHBT1
Rho-related BTB domain-containing protein 1

1

6

High-throughput

0.437

High

385479

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.437

High

683688

1433B
14-3-3 protein beta/alpha

1

16

High-throughput

0.437

High

813729

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.437

High

932365

ACTC
Actin, alpha cardiac muscle 1

1

6

High-throughput

0.437

High

1171593

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.437

High

1206044

MIB1
E3 ubiquitin-protein ligase MIB1

1

2

High-throughput

0.437

High

1316730

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.437

High

1317621

RHBT2
Rho-related BTB domain-containing protein 2

1

7

High-throughput

0.437

High

1318152

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.437

High

1318154

CASS4
Cas scaffolding protein family member 4

1

4

High-throughput

0.417

High

965145

ANK2
Ankyrin-2

1

0

High-throughput

0.279

Low

1266759

NICA
Nicastrin

1

0

High-throughput

0.279

Low

879548

BID
BH3-interacting domain death agonist

1

0

High-throughput

0.265

Low

538816

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

1

0

High-throughput

0.249

Low

1047250

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024