Protein: X3CL1
Fractalkine (C-X3-C motif chemokine 1) (CX3C membrane-anchored chemokine) (Neurotactin) (Small-inducible cytokine D1) [Cleaved into: Processed fractalkine]

Gene: X3CL1, CX3CL1
Organism: Homo sapiens
Interactions: 78
UniProt ID: P78423

Gene Ontology (top 5):
GO:0001774 - microglial cell activation
GO:0001954 - positive regulation of cell-matrix adhesion
GO:0002052 - positive regulation of neuroblast proliferation
GO:0002523 - leukocyte migration involved in inflammatory response
GO:0002548 - monocyte chemotaxis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

825305

CX3C1
CX3C chemokine receptor 1

4

0

Small-scale

0.833

High

396580

ITB3
Integrin beta-3

2

4

Small-scale

0.612

High

943967

X3CL1
Fractalkine

1

0

Small-scale

0.546

High

129274

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

2

High-throughput

0.536

High

383737

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

1

High-throughput

0.536

High

530866

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.536

High

607936

FGFR4
Fibroblast growth factor receptor 4

1

1

High-throughput

0.536

High

616787

JAK1
Tyrosine-protein kinase JAK1

1

2

High-throughput

0.536

High

727446

ATP7B
Copper-transporting ATPase 2

1

2

High-throughput

0.536

High

729259

VGFR3
Vascular endothelial growth factor receptor 3

1

1

High-throughput

0.536

High

871890

AT12A
Potassium-transporting ATPase alpha chain 2

1

1

High-throughput

0.536

High

943971

ATP7A
Copper-transporting ATPase 1

1

2

High-throughput

0.536

High

943980

FAT4
Protocadherin Fat 4

1

1

High-throughput

0.536

High

943994

FAT3
Protocadherin Fat 3

1

1

High-throughput

0.536

High

943997

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

2

High-throughput

0.536

High

944003

S12A9
Solute carrier family 12 member 9

1

1

High-throughput

0.536

High

944004

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

1

High-throughput

0.536

High

944008

S12A4
Solute carrier family 12 member 4

1

1

High-throughput

0.536

High

403856

ITB1
Integrin beta-1

1

4

Small-scale

0.515

High

68162

F1712
Protein FAM171A2

1

0

High-throughput

0.513

High

151562

GOSR2
Golgi SNAP receptor complex member 2

1

0

High-throughput

0.513

High

178478

STX7
Syntaxin-7

1

0

High-throughput

0.513

High

179348

MRP4
ATP-binding cassette sub-family C member 4

1

0

High-throughput

0.513

High

200738

ADCY6
Adenylate cyclase type 6

1

0

High-throughput

0.513

High

259275

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

0

High-throughput

0.513

High

309469

MTMR5
Myotubularin-related protein 5

1

0

High-throughput

0.513

High

522905

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.513

High

546451

INGR1
Interferon gamma receptor 1

1

0

High-throughput

0.513

High

565351

TMM11
Transmembrane protein 11, mitochondrial

1

0

High-throughput

0.513

High

586030

SL9A1
Sodium/hydrogen exchanger 1

1

0

High-throughput

0.513

High

622781

COT2
COUP transcription factor 2

1

0

High-throughput

0.513

High

738329

BMR1A
Bone morphogenetic protein receptor type-1A

1

0

High-throughput

0.513

High

820294

SPB4
Serpin B4

1

0

High-throughput

0.513

High

863923

CLH2
Clathrin heavy chain 2

1

0

High-throughput

0.513

High

943968

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

0

High-throughput

0.513

High

943969

AT8B2
Phospholipid-transporting ATPase ID

1

0

High-throughput

0.513

High

943973

DIP2A
Disco-interacting protein 2 homolog A

1

0

High-throughput

0.513

High

943974

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.513

High

943975

CEGT
Ceramide glucosyltransferase

1

0

High-throughput

0.513

High

943976

WDR44
WD repeat-containing protein 44

1

0

High-throughput

0.513

High

943978

PKN3
Serine/threonine-protein kinase N3

1

0

High-throughput

0.513

High

943979

RHDF2
Inactive rhomboid protein 2

1

0

High-throughput

0.513

High

943981

PKHH3
Pleckstrin homology domain-containing family H member 3

1

0

High-throughput

0.513

High

943983

LAP4B
Lysosomal-associated transmembrane protein 4B

1

0

High-throughput

0.513

High

943984

ZDH13
Palmitoyltransferase ZDHHC13

1

0

High-throughput

0.513

High

943985

ARL17
ADP-ribosylation factor-like protein 17

1

0

High-throughput

0.513

High

943987

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.513

High

943989

MSPD2
Motile sperm domain-containing protein 2

1

0

High-throughput

0.513

High

943990

SMS2
Phosphatidylcholine:ceramide cholinephosphotransferase 2

1

0

High-throughput

0.513

High

943991

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

0

High-throughput

0.513

High

943993

CERK1
Ceramide kinase

1

0

High-throughput

0.513

High

943995

S20A1
Sodium-dependent phosphate transporter 1

1

0

High-throughput

0.513

High

943996

S35F5
Solute carrier family 35 member F5

1

0

High-throughput

0.513

High

944000

PANX1
Pannexin-1

1

0

High-throughput

0.513

High

944001

S29A1
Equilibrative nucleoside transporter 1

1

0

High-throughput

0.513

High

944002

NFIP1
NEDD4 family-interacting protein 1

1

0

High-throughput

0.513

High

944005

TEN3
Teneurin-3

1

0

High-throughput

0.513

High

944007

STX8
Syntaxin-8

1

0

High-throughput

0.513

High

944009

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

0

High-throughput

0.513

High

944011

S4A7
Sodium bicarbonate cotransporter 3

1

0

High-throughput

0.513

High

943970

TF65
Transcription factor p65

1

0

Small-scale

0.493

High

943972

STX5
Syntaxin-5

1

1

High-throughput

0.489

High

943999

C1GLC
C1GALT1-specific chaperone 1

1

1

High-throughput

0.489

High

396622

ITB2
Integrin beta-2

1

4

Small-scale

0.479

High

556432

ITB4
Integrin beta-4

1

3

Small-scale

0.479

High

443070

ITA5
Integrin alpha-5

1

0

Small-scale

0.458

High

217251

ORC5
Origin recognition complex subunit 5

1

0

High-throughput

0.279

Low

301193

RHBT3
Rho-related BTB domain-containing protein 3

1

0

High-throughput

0.279

Low

648487

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

943977

ACD10
Acyl-CoA dehydrogenase family member 10

1

0

High-throughput

0.279

Low

943982

NOP9
Nucleolar protein 9

1

0

High-throughput

0.279

Low

943986

DEN6A
Protein DENND6A

1

0

High-throughput

0.279

Low

943988

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

0

High-throughput

0.279

Low

943992

WDR20
WD repeat-containing protein 20

1

0

High-throughput

0.279

Low

943998

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

1

0

High-throughput

0.279

Low

944006

TRM7
tRNA

1

0

High-throughput

0.279

Low

944010

ZDHC9
Palmitoyltransferase ZDHHC9

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024