Protein: XPP1
Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)

Gene: XPP1, XPNPEP1
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q9NQW7

Gene Ontology (top 5):
GO:0004177 - aminopeptidase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0010815 - bradykinin catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1308688

SPI2B
Spindlin-2B

3

2

High-throughput

0.667

High

883733

WDR4
tRNA

2

5

High-throughput

0.628

High

1076776

RHOH
Rho-related GTP-binding protein RhoH

2

3

High-throughput

0.606

High

900945

RHOA
Transforming protein RhoA

2

2

High-throughput

0.601

High

1343876

DISC1
Disrupted in schizophrenia 1 protein

2

1

High-throughput

0.590

High

936027

HBG2
Hemoglobin subunit gamma-2

2

0

High-throughput

0.580

High

800946

MK09
Mitogen-activated protein kinase 9

1

3

High-throughput

0.541

High

361931

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

1

High-throughput

0.536

High

1077867

MYLK
Myosin light chain kinase, smooth muscle

1

1

High-throughput

0.536

High

1050456

DPOA2
DNA polymerase alpha subunit B

1

0

High-throughput

0.518

High

574449

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

578863

SDC1
Syndecan-1

1

0

High-throughput

0.513

High

836016

GSK3B
Glycogen synthase kinase-3 beta

1

2

High-throughput

0.508

High

476430

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.501

High

839866

CSRP3
Cysteine and glycine-rich protein 3

1

0

High-throughput

0.493

High

1287672

DDT4L
DNA damage-inducible transcript 4-like protein

1

0

High-throughput

0.493

High

672740

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.489

High

679023

HXC12
Homeobox protein Hox-C12

1

3

High-throughput

0.489

High

329130

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.486

High

895923

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

0

High-throughput

0.486

High

228797

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

324633

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.479

High

360449

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.479

High

374939

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

385570

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.479

High

780159

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

1043243

CUL4A
Cullin-4A

1

6

High-throughput

0.479

High

1171855

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

1343878

PKHG1
Pleckstrin homology domain-containing family G member 1

1

1

High-throughput

0.479

High

417429

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

504811

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

1313487

DUS26
Dual specificity protein phosphatase 26

1

0

High-throughput

0.458

High

902765

SUMO2
Small ubiquitin-related modifier 2

1

2

High-throughput

0.457

High

497640

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.445

High

1130626

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

1156522

RINT1
RAD50-interacting protein 1

1

0

High-throughput

0.438

High

101208

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

553808

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

652341

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

721534

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

378181

PRIO
Major prion protein

1

0

High-throughput

0.426

High

1078281

RAB30
Ras-related protein Rab-30

2

0

High-throughput

0.328

High

1333930

GORS2
Golgi reassembly-stacking protein 2

2

0

High-throughput

0.316

High

68318

P20L1
PHD finger protein 20-like protein 1

1

0

High-throughput

0.279

Low

70787

VWC2L
von Willebrand factor C domain-containing protein 2-like

1

0

High-throughput

0.279

Low

1245055

STXB6
Syntaxin-binding protein 6

1

0

High-throughput

0.279

Low

1298887

GUCD1
Protein GUCD1

1

0

High-throughput

0.279

Low

1343877

GDE1
Glycerophosphodiester phosphodiesterase 1

1

0

High-throughput

0.279

Low

329962

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024