Protein: CD2B2
CD2 antigen cytoplasmic tail-binding protein 2 (CD2 cytoplasmic domain-binding protein 2) (CD2 tail-binding protein 2) (U5 snRNP 52K protein) (U5-52K)

Gene: CD2B2, CD2BP2
Organism: Homo sapiens
Interactions: 215
UniProt ID: O95400

Gene Ontology (top 5):
GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0001650 - fibrillar center
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005682 - U5 snRNP

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

313255

TXN4A
Thioredoxin-like protein 4A

5

0

Small-scale

0.887

High

313214

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

11

4

Small-scale

0.762

High

300018

PRP6
Pre-mRNA-processing factor 6

10

2

Small-scale

0.760

High

313302

PRP8
Pre-mRNA-processing-splicing factor 8

8

1

High-throughput

0.750

High

313334

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

7

1

High-throughput

0.747

High

271996

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

6

6

High-throughput

0.735

High

313347

DDX23
Probable ATP-dependent RNA helicase DDX23

6

1

High-throughput

0.735

High

313251

RSMN
Small nuclear ribonucleoprotein-associated protein N

5

4

Small-scale

0.717

High

313241

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

5

2

Small-scale

0.714

High

313207

CD2
T-cell surface antigen CD2

6

0

Small-scale

0.713

High

313306

ACD11
Acyl-CoA dehydrogenase family member 11

6

0

High-throughput

0.704

High

313283

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

6

0

High-throughput

0.704

High

313245

RUXF
Small nuclear ribonucleoprotein F

4

2

High-throughput

0.702

High

313247

SMD1
Small nuclear ribonucleoprotein Sm D1

4

3

High-throughput

0.699

High

313327

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

4

2

High-throughput

0.699

High

313295

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

5

0

High-throughput

0.688

High

313230

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

3

2

High-throughput

0.677

High

313244

RUXE
Small nuclear ribonucleoprotein E

4

0

High-throughput

0.670

High

313296

EAPP
E2F-associated phosphoprotein

4

0

High-throughput

0.670

High

313381

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

4

0

High-throughput

0.664

High

313246

RUXG
Small nuclear ribonucleoprotein G

3

6

High-throughput

0.662

High

313293

SMU1
WD40 repeat-containing protein SMU1

3

2

High-throughput

0.650

High

313222

SFPQ
Splicing factor, proline- and glutamine-rich

3

2

Small-scale

0.647

High

313248

SMD2
Small nuclear ribonucleoprotein Sm D2

3

0

High-throughput

0.646

High

199635

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

3

0

High-throughput

0.638

High

313279

NAA30
N-alpha-acetyltransferase 30

3

0

High-throughput

0.638

High

313376

WBP11
WW domain-binding protein 11

2

1

Small-scale

0.620

High

313211

SNRPA
U1 small nuclear ribonucleoprotein A

2

2

Small-scale

0.619

High

196932

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

2

3

High-throughput

0.611

High

313249

SMD3
Small nuclear ribonucleoprotein Sm D3

2

3

High-throughput

0.611

High

313290

SF3A1
Splicing factor 3A subunit 1

2

1

High-throughput

0.611

High

313345

RBM42
RNA-binding protein 42

2

1

High-throughput

0.611

High

313377

AAR2
Protein AAR2 homolog

2

1

High-throughput

0.611

High

313294

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

1

High-throughput

0.602

High

255398

OBSL1
Obscurin-like protein 1

2

0

High-throughput

0.602

High

313258

EWS
RNA-binding protein EWS

2

1

High-throughput

0.601

High

313196

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.586

High

202348

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

2

0

High-throughput

0.585

High

313237

MFAP1
Microfibrillar-associated protein 1

2

0

High-throughput

0.585

High

313272

SNW1
SNW domain-containing protein 1

2

0

High-throughput

0.585

High

313360

TLS1
Splicing factor C9orf78

2

0

High-throughput

0.585

High

276573

TPC6A
Trafficking protein particle complex subunit 6A

2

0

High-throughput

0.580

High

313303

TRAF7
E3 ubiquitin-protein ligase TRAF7

2

2

High-throughput

0.574

High

313288

SF3B4
Splicing factor 3B subunit 4

2

0

Small-scale

0.569

High

243746

BRD4
Bromodomain-containing protein 4

2

0

High-throughput

0.559

High

313210

RU17
U1 small nuclear ribonucleoprotein 70 kDa

2

0

High-throughput

0.559

High

313206

FYN
Tyrosine-protein kinase Fyn

2

0

High-throughput

0.547

High

313320

ARH40
Rho guanine nucleotide exchange factor 40

2

0

High-throughput

0.547

High

313252

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.545

High

313216

GCFC2
Intron Large complex component GCFC2

1

1

High-throughput

0.536

High

313276

RBM39
RNA-binding protein 39

1

2

High-throughput

0.536

High

313282

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.536

High

313311

DDX42
ATP-dependent RNA helicase DDX42

1

2

High-throughput

0.536

High

313358

RBM22
Pre-mRNA-splicing factor RBM22

1

1

High-throughput

0.536

High

313359

BCLF1
Bcl-2-associated transcription factor 1

1

1

High-throughput

0.536

High

313375

TR150
Thyroid hormone receptor-associated protein 3

1

2

High-throughput

0.536

High

313380

PAXB1
PAX3- and PAX7-binding protein 1

1

1

High-throughput

0.536

High

313309

AKNA
Microtubule organization protein AKNA

1

0

Small-scale

0.531

High

313382

MAGD1
Melanoma-associated antigen D1

1

0

Small-scale

0.531

High

313326

PSMF1
Proteasome inhibitor PI31 subunit

1

0

Small-scale

0.529

High

313274

IF4A2
Eukaryotic initiation factor 4A-II

1

1

High-throughput

0.515

High

313368

PUF60
Poly(U)-binding-splicing factor PUF60

1

1

High-throughput

0.515

High

313200

KAD1
Adenylate kinase isoenzyme 1

1

0

High-throughput

0.513

High

313212

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

313227

NKTR
NK-tumor recognition protein

1

0

High-throughput

0.513

High

313234

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.513

High

313256

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.513

High

313264

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

313273

CUL3
Cullin-3

1

0

High-throughput

0.513

High

313275

FA50A
Protein FAM50A

1

0

High-throughput

0.513

High

313280

KIF22
Kinesin-like protein KIF22

1

0

High-throughput

0.513

High

313322

CCD12
Coiled-coil domain-containing protein 12

1

0

High-throughput

0.513

High

313338

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.513

High

313343

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.513

High

313350

PININ
Pinin

1

0

High-throughput

0.513

High

313362

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.513

High

313363

POLK
DNA polymerase kappa

1

0

High-throughput

0.513

High

174510

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

313261

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

1

Small-scale

0.501

High

313285

Q15182
Small nuclear ribonucleoprotein-associated protein

1

4

Small-scale

0.501

High

313291

SF01
Splicing factor 1

1

1

Small-scale

0.501

High

313297

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.501

High

214811

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.493

High

313208

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.493

High

313235

KHK
Ketohexokinase

1

0

High-throughput

0.493

High

313277

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

1

0

High-throughput

0.493

High

313312

CRERF
CREB3 regulatory factor

1

0

High-throughput

0.493

High

313333

CMBL
Carboxymethylenebutenolidase homolog

1

0

High-throughput

0.493

High

313315

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

1

High-throughput

0.481

High

203193

SYNJ1
Synaptojanin-1

1

0

Small-scale

0.480

High

313233

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

Small-scale

0.480

High

313356

RBM12
RNA-binding protein 12

1

0

Small-scale

0.480

High

195297

DHX15
ATP-dependent RNA helicase DHX15

1

2

High-throughput

0.479

High

209369

PLRG1
Pleiotropic regulator 1

1

3

High-throughput

0.479

High

212089

HTSF1
17S U2 SnRNP complex component HTATSF1

1

2

High-throughput

0.479

High

238620

IMA7
Importin subunit alpha-7

1

1

High-throughput

0.479

High

313199

ECD
Protein ecdysoneless homolog

1

1

High-throughput

0.479

High

313203

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

313209

RU2B
U2 small nuclear ribonucleoprotein B''

1

2

High-throughput

0.479

High

313213

RU2A
U2 small nuclear ribonucleoprotein A'

1

1

High-throughput

0.479

High

313215

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

313220

DDX5
Probable ATP-dependent RNA helicase DDX5

1

2

High-throughput

0.479

High

313236

IMA5
Importin subunit alpha-5

1

1

High-throughput

0.479

High

313242

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

2

High-throughput

0.479

High

313259

TLE3
Transducin-like enhancer protein 3

1

3

High-throughput

0.479

High

313260

SRS11
Serine/arginine-rich splicing factor 11

1

1

High-throughput

0.479

High

313262

SRSF1
Serine/arginine-rich splicing factor 1

1

2

High-throughput

0.479

High

313263

SRSF4
Serine/arginine-rich splicing factor 4

1

2

High-throughput

0.479

High

313266

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

313268

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

313269

SRSF6
Serine/arginine-rich splicing factor 6

1

2

High-throughput

0.479

High

313278

DHX8
ATP-dependent RNA helicase DHX8

1

2

High-throughput

0.479

High

313286

NONO
Non-POU domain-containing octamer-binding protein

1

2

High-throughput

0.479

High

313289

SF3A2
Splicing factor 3A subunit 2

1

1

High-throughput

0.479

High

313305

PAXI1
PAX-interacting protein 1

1

1

High-throughput

0.479

High

313307

DDX46
Probable ATP-dependent RNA helicase DDX46

1

2

High-throughput

0.479

High

313310

ZCH18
Zinc finger CCCH domain-containing protein 18

1

3

High-throughput

0.479

High

313313

SRRM1
Serine/arginine repetitive matrix protein 1

1

2

High-throughput

0.479

High

313316

NUP43
Nucleoporin Nup43

1

3

High-throughput

0.479

High

313317

NEDD1
Protein NEDD1

1

3

High-throughput

0.479

High

313325

PSPC1
Paraspeckle component 1

1

2

High-throughput

0.479

High

313330

ARMC5
Armadillo repeat-containing protein 5

1

1

High-throughput

0.479

High

313332

GCP3
Gamma-tubulin complex component 3

1

4

High-throughput

0.479

High

313339

GCP6
Gamma-tubulin complex component 6

1

4

High-throughput

0.479

High

313340

GCP5
Gamma-tubulin complex component 5

1

4

High-throughput

0.479

High

313341

RANB9
Ran-binding protein 9

1

1

High-throughput

0.479

High

313344

GCP2
Gamma-tubulin complex component 2

1

4

High-throughput

0.479

High

313346

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

1

High-throughput

0.479

High

313365

GCP4
Gamma-tubulin complex component 4

1

4

High-throughput

0.479

High

313366

DDX20
Probable ATP-dependent RNA helicase DDX20

1

4

High-throughput

0.479

High

313372

FZR1
Fizzy-related protein homolog

1

2

High-throughput

0.479

High

313373

PRP19
Pre-mRNA-processing factor 19

1

3

High-throughput

0.479

High

313378

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

3

High-throughput

0.479

High

313383

RA54B
DNA repair and recombination protein RAD54B

1

1

High-throughput

0.479

High

313197

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.460

High

313331

AP2M1
AP-2 complex subunit mu

1

0

High-throughput

0.460

High

313349

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.460

High

122425

MEN1
Menin

1

0

High-throughput

0.458

High

130676

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.458

High

165364

SR140
U2 snRNP-associated SURP motif-containing protein

1

0

High-throughput

0.458

High

230695

AQR
RNA helicase aquarius

1

0

High-throughput

0.458

High

268360

BAF
Barrier-to-autointegration factor

1

0

Small-scale

0.458

High

268559

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.458

High

301344

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

0

High-throughput

0.458

High

302747

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

304463

FSBP
Fibrinogen silencer-binding protein

1

0

High-throughput

0.458

High

312877

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.458

High

313198

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

313201

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

313202

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

Small-scale

0.458

High

313205

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

313218

CXA1
Gap junction alpha-1 protein

1

0

Small-scale

0.458

High

313219

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

313223

TBG1
Tubulin gamma-1 chain

1

0

High-throughput

0.458

High

313224

CCND1
G1/S-specific cyclin-D1

1

0

High-throughput

0.458

High

313225

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

313226

RBL1
Retinoblastoma-like protein 1

1

0

High-throughput

0.458

High

313229

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

313231

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

313232

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

313238

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

313239

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.458

High

313240

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

313243

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

313250

H4
Histone H4

1

0

High-throughput

0.458

High

313257

VIGLN
Vigilin

1

0

High-throughput

0.458

High

313265

SF3A3
Splicing factor 3A subunit 3

1

0

High-throughput

0.458

High

313267

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

313270

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.458

High

313271

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

0

High-throughput

0.458

High

313281

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

313284

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

313287

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.458

High

313292

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

313300

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.458

High

313301

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

313304

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

313308

PHF5A
PHD finger-like domain-containing protein 5A

1

0

High-throughput

0.458

High

313318

SP7
Transcription factor Sp7

1

0

High-throughput

0.458

High

313319

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

313321

PNISR
Arginine/serine-rich protein PNISR

1

0

High-throughput

0.458

High

313323

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.458

High

313324

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

0

High-throughput

0.458

High

313328

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

313335

CDCA5
Sororin

1

0

High-throughput

0.458

High

313337

TOE1
Target of EGR1 protein 1

1

0

High-throughput

0.458

High

313342

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.458

High

313348

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

313351

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

313352

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

313353

CWC22
Pre-mRNA-splicing factor CWC22 homolog

1

0

High-throughput

0.458

High

313354

ANLN
Anillin

1

0

High-throughput

0.458

High

313355

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

313357

NLE1
Notchless protein homolog 1

1

0

High-throughput

0.458

High

313361

IBTK
Inhibitor of Bruton tyrosine kinase

1

0

High-throughput

0.458

High

313364

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

313369

GPTC8
G patch domain-containing protein 8

1

0

High-throughput

0.458

High

313370

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

0

High-throughput

0.458

High

313371

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.458

High

313374

SRRM2
Serine/arginine repetitive matrix protein 2

1

0

High-throughput

0.458

High

68391

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

6

High-throughput

0.445

High

313299

PR38B
Pre-mRNA-splicing factor 38B

1

1

High-throughput

0.437

High

313228

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

313336

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

313367

ZNHI2
Zinc finger HIT domain-containing protein 2

4

0

High-throughput

0.361

High

313314

KLH36
Kelch-like protein 36

3

0

High-throughput

0.347

High

313221

ACM3
Muscarinic acetylcholine receptor M3

1

0

High-throughput

0.282

High

313217

BPI
Bactericidal permeability-increasing protein

1

0

High-throughput

0.279

Low

313329

K1143
Uncharacterized protein KIAA1143

1

0

High-throughput

0.279

Low

313253

DCD
Dermcidin

1

0

High-throughput

0.269

Low

313204

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

313254

CRUM1
Protein crumbs homolog 1

1

0

High-throughput

0.249

Low

313298

RC3H1
Roquin-1

1

0

High-throughput

0.249

Low

313379

TCAF1
TRPM8 channel-associated factor 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024