Protein: NR1H2
Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear receptor NER) (Nuclear receptor subfamily 1 group H member 2) (Ubiquitously-expressed nuclear receptor)

Gene: NR1H2
Organism: Homo sapiens
Interactions: 69
UniProt ID: P55055

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

818867

RXRG
Retinoic acid receptor RXR-gamma

9

20

High-throughput

0.969

High

587144

RXRA
Retinoic acid receptor RXR-alpha

5

20

Small-scale

0.922

High

659698

RXRB
Retinoic acid receptor RXR-beta

4

20

Small-scale

0.873

High

874382

NR0B2
Nuclear receptor subfamily 0 group B member 2

2

18

Small-scale

0.768

High

874392

MDFI
MyoD family inhibitor

4

2

High-throughput

0.698

High

740483

PPARG
Peroxisome proliferator-activated receptor gamma

1

19

Small-scale

0.692

High

874376

PPARD
Peroxisome proliferator-activated receptor delta

1

20

Small-scale

0.692

High

874377

PPARA
Peroxisome proliferator-activated receptor alpha

1

20

Small-scale

0.692

High

261450

NCOR1
Nuclear receptor corepressor 1

3

20

Small-scale

0.661

High

315243

ABCA1
Phospholipid-transporting ATPase ABCA1

3

3

Small-scale

0.633

High

487928

RARA
Retinoic acid receptor alpha

1

17

High-throughput

0.621

High

509927

VDR
Vitamin D3 receptor

1

20

High-throughput

0.621

High

874384

NCOA1
Nuclear receptor coactivator 1

1

20

High-throughput

0.621

High

874407

NCOA3
Nuclear receptor coactivator 3

1

20

High-throughput

0.621

High

874381

NCOA6
Nuclear receptor coactivator 6

2

20

Small-scale

0.609

High

874383

MED1
Mediator of RNA polymerase II transcription subunit 1

2

20

Small-scale

0.594

High

874405

NCOR2
Nuclear receptor corepressor 2

2

20

Small-scale

0.594

High

874396

ROBO2
Roundabout homolog 2

1

3

High-throughput

0.587

High

739521

ACVL1
Serine/threonine-protein kinase receptor R3

1

2

Small-scale

0.586

High

278004

PIAS1
E3 SUMO-protein ligase PIAS1

2

11

Small-scale

0.584

High

351872

NPY
Pro-neuropeptide Y [Cleaved into: Neuropeptide Y

3

1

High-throughput

0.583

High

232067

KDM1A
Lysine-specific histone demethylase 1A

1

13

High-throughput

0.573

High

632661

TYY1
Transcriptional repressor protein YY1

1

10

High-throughput

0.541

High

758164

CDN1A
Cyclin-dependent kinase inhibitor 1

1

4

High-throughput

0.541

High

865024

TTC3
E3 ubiquitin-protein ligase TTC3

1

12

High-throughput

0.541

High

874379

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

6

Small-scale

0.536

High

874373

HDAC4
Histone deacetylase 4

1

20

Small-scale

0.536

High

874394

SENP3
Sentrin-specific protease 3

1

3

Small-scale

0.515

High

203652

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

20

High-throughput

0.508

High

208113

SPY2
Protein sprouty homolog 2

1

5

High-throughput

0.508

High

298963

SRBS2
Sorbin and SH3 domain-containing protein 2

1

14

High-throughput

0.508

High

443425

VIME
Vimentin

1

19

High-throughput

0.508

High

874378

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.508

High

874395

RMI1
RecQ-mediated genome instability protein 1

1

1

High-throughput

0.508

High

874399

HMGX4
HMG domain-containing protein 4

1

14

High-throughput

0.508

High

874403

FAF1
FAS-associated factor 1

1

2

High-throughput

0.508

High

874404

CSAD
Cysteine sulfinic acid decarboxylase

1

3

High-throughput

0.508

High

874390

COR2A
Coronin-2A

1

20

Small-scale

0.503

High

566337

KPCA
Protein kinase C alpha type

1

10

Small-scale

0.501

High

874387

RHOU
Rho-related GTP-binding protein RhoU

1

7

High-throughput

0.501

High

874400

DNM3L
DNA

1

6

Small-scale

0.501

High

874406

LAMC3
Laminin subunit gamma-3

1

4

High-throughput

0.494

High

567442

ASM
Sphingomyelin phosphodiesterase

1

0

High-throughput

0.486

High

849297

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

0

High-throughput

0.486

High

874402

DUS12
Dual specificity protein phosphatase 12

1

0

High-throughput

0.486

High

206818

FOXO3
Forkhead box protein O3

1

20

High-throughput

0.481

High

803455

BAG6
Large proline-rich protein BAG6

1

20

High-throughput

0.481

High

819605

NRIP1
Nuclear receptor-interacting protein 1

1

17

High-throughput

0.481

High

874374

UBC9
SUMO-conjugating enzyme UBC9

1

10

High-throughput

0.481

High

874385

ZXDC
Zinc finger protein ZXDC

1

4

High-throughput

0.481

High

874398

ING3
Inhibitor of growth protein 3

1

11

High-throughput

0.481

High

236531

CIDEA
Lipid transferase CIDEA

1

0

Small-scale

0.480

High

122587

MEN1
Menin

1

7

Small-scale

0.479

High

206342

LTOR5
Ragulator complex protein LAMTOR5

1

2

Small-scale

0.479

High

786285

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

14

Small-scale

0.479

High

846907

SMCA4
Transcription activator BRG1

1

20

Small-scale

0.479

High

874372

SUMO3
Small ubiquitin-related modifier 3

1

9

Small-scale

0.479

High

874380

CUL3
Cullin-3

1

10

High-throughput

0.479

High

874389

PRGC2
Peroxisome proliferator-activated receptor gamma coactivator 1-beta

1

20

Small-scale

0.479

High

874391

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

20

Small-scale

0.479

High

874393

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

874375

EM55
55 kDa erythrocyte membrane protein

1

4

High-throughput

0.464

High

401245

7B2
Neuroendocrine protein 7B2

1

0

High-throughput

0.460

High

874388

ABCAC
Glucosylceramide transporter ABCA12

1

3

Small-scale

0.445

High

158316

PCD17
Protocadherin-17

1

2

High-throughput

0.439

High

874397

T161A
Transmembrane protein 161A

1

2

High-throughput

0.439

High

874386

CREL2
Protein disulfide isomerase CRELD2

1

2

High-throughput

0.417

High

666801

CO4A5

1

0

High-throughput

0.265

Low

874401

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.265

Low


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Last updated: 15 Jul 2024