Protein: TOE1
Target of EGR1 protein 1

Gene: TOE1
Organism: Homo sapiens
Interactions: 143
UniProt ID: Q96GM8

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0004535 - poly(A)-specific ribonuclease activity
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

442394

RU17
U1 small nuclear ribonucleoprotein 70 kDa

3

5

High-throughput

0.861

High

1063266

SART3
Squamous cell carcinoma antigen recognized by T-cells 3

2

3

High-throughput

0.811

High

197072

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

1

High-throughput

0.691

High

441347

RU2B
U2 small nuclear ribonucleoprotein B''

1

3

High-throughput

0.691

High

446742

SNRPA
U1 small nuclear ribonucleoprotein A

1

5

High-throughput

0.691

High

945319

PRR3
Proline-rich protein 3

1

1

High-throughput

0.691

High

993799

SRSF4
Serine/arginine-rich splicing factor 4

1

4

High-throughput

0.691

High

1084569

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

4

High-throughput

0.691

High

1116453

LARP7
La-related protein 7

1

7

High-throughput

0.691

High

1292545

RBM19
Probable RNA-binding protein 19

1

6

High-throughput

0.691

High

911931

RUXF
Small nuclear ribonucleoprotein F

3

2

High-throughput

0.675

High

971303

H11
Histone H1.1

3

5

High-throughput

0.667

High

855172

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

7

High-throughput

0.656

High

1029036

SRSF6
Serine/arginine-rich splicing factor 6

1

5

High-throughput

0.656

High

1054507

RBM39
RNA-binding protein 39

1

4

High-throughput

0.656

High

1292525

MEP50
Methylosome protein WDR77

1

1

High-throughput

0.656

High

1292547

RBM8A
RNA-binding protein 8A

1

4

High-throughput

0.656

High

347582

MYC
Myc proto-oncogene protein

3

2

High-throughput

0.640

High

305085

SPN1
Snurportin-1

3

0

High-throughput

0.638

High

453888

RU2A
U2 small nuclear ribonucleoprotein A'

3

0

High-throughput

0.638

High

550898

RS2
Small ribosomal subunit protein uS5

3

0

High-throughput

0.638

High

539102

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

1

High-throughput

0.628

High

927997

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

1

High-throughput

0.628

High

963255

U2AF1
Splicing factor U2AF 35 kDa subunit

1

0

High-throughput

0.622

High

1034369

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.622

High

1073109

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.622

High

1073830

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

5

High-throughput

0.618

High

282993

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

2

High-throughput

0.618

High

726985

FUS
RNA-binding protein FUS

1

6

High-throughput

0.618

High

967355

EWS
RNA-binding protein EWS

1

2

High-throughput

0.618

High

1271163

RBP56
TATA-binding protein-associated factor 2N

1

2

High-throughput

0.618

High

1288232

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

2

High-throughput

0.618

High

1292530

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

5

High-throughput

0.618

High

912093

RUXG
Small nuclear ribonucleoprotein G

2

4

High-throughput

0.611

High

911716

RUXE
Small nuclear ribonucleoprotein E

2

0

High-throughput

0.602

High

1292529

WDR83
WD repeat domain-containing protein 83

1

1

High-throughput

0.587

High

374687

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

1

High-throughput

0.584

High

489199

H14
Histone H1.4

2

5

High-throughput

0.574

High

608610

H1T
Histone H1t

2

5

High-throughput

0.574

High

370198

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

387295

P53
Cellular tumor antigen p53

1

2

Small-scale

0.568

High

1146727

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.553

High

849946

APLP1
Amyloid beta precursor like protein 1

1

2

High-throughput

0.541

High

928166

SUMO1
Small ubiquitin-related modifier 1

1

1

High-throughput

0.541

High

1292524

SH3G3
Endophilin-A3

1

2

High-throughput

0.541

High

273206

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.536

High

448778

RU1C
U1 small nuclear ribonucleoprotein C

1

1

High-throughput

0.536

High

456242

IFIT2
Interferon-induced protein with tetratricopeptide repeats 2

1

2

High-throughput

0.536

High

456292

IFIT1
Interferon-induced protein with tetratricopeptide repeats 1

1

2

High-throughput

0.536

High

559212

H15
Histone H1.5

1

5

High-throughput

0.536

High

759776

RS19
Small ribosomal subunit protein eS19

1

1

High-throughput

0.536

High

908086

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.536

High

912705

SMD3
Small nuclear ribonucleoprotein Sm D3

1

2

High-throughput

0.536

High

916311

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.536

High

922305

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.536

High

942868

SRPK2
SRSF protein kinase 2

1

2

High-throughput

0.536

High

1040643

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.536

High

1292534

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.536

High

1292540

ZBT47
Zinc finger and BTB domain-containing protein 47

1

2

High-throughput

0.536

High

1292543

YBOX2
Y-box-binding protein 2

1

1

High-throughput

0.536

High

898433

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.518

High

395473

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.515

High

225936

FGF17
Fibroblast growth factor 17

1

0

High-throughput

0.513

High

241798

CCD22
Coiled-coil domain-containing protein 22

1

0

High-throughput

0.513

High

616462

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.513

High

806966

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

807478

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.513

High

913683

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.513

High

951698

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

1042271

CUL3
Cullin-3

1

0

High-throughput

0.513

High

1070196

RASA2
Ras GTPase-activating protein 2

1

0

High-throughput

0.513

High

1193008

ZN467
Zinc finger protein 467

1

0

High-throughput

0.513

High

1202051

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

1291153

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

1292522

ZN668
Zinc finger protein 668

1

0

High-throughput

0.513

High

1292527

LLPH
Protein LLP homolog

1

0

High-throughput

0.513

High

1292528

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.513

High

1292539

PIM2
Serine/threonine-protein kinase pim-2

1

0

High-throughput

0.513

High

1292542

ZN346
Zinc finger protein 346

1

0

High-throughput

0.513

High

1231916

AGGF1
Angiogenic factor with G patch and FHA domains 1

1

1

High-throughput

0.508

High

1292546

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

2

High-throughput

0.508

High

1292537

ABCF3
ATP-binding cassette sub-family F member 3

1

1

High-throughput

0.494

High

180406

MAGB2
Melanoma-associated antigen B2

1

3

High-throughput

0.489

High

470502

H2A1
Histone H2A type 1

1

2

High-throughput

0.489

High

559467

H13
Histone H1.3

1

5

High-throughput

0.489

High

906075

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

High-throughput

0.486

High

1024939

RED
Protein Red

1

0

High-throughput

0.486

High

1270075

PRCC
Proline-rich protein PRCC

1

0

High-throughput

0.486

High

175115

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

125646

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

1

High-throughput

0.479

High

228347

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

322996

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

379723

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.479

High

455758

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

651949

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

721153

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

898707

RL26
Large ribosomal subunit protein uL24

1

1

High-throughput

0.479

High

959598

VIGLN
Vigilin

1

1

High-throughput

0.479

High

998974

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.479

High

1064030

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

1171226

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

1240929

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1269352

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

1270872

KAT6A
Histone acetyltransferase KAT6A

1

1

High-throughput

0.479

High

1292531

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

1292533

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1292541

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

122933

MEN1
Menin

1

0

High-throughput

0.458

High

149167

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

313337

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.458

High

760230

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

824278

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

1029733

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1064597

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1080228

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1193152

SLN11
Schlafen family member 11

1

0

Small-scale

0.458

High

1256329

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1292521

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1292526

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

1292535

ANLN
Anillin

1

0

High-throughput

0.458

High

1292536

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1292538

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

243552

DNJA2
DnaJ homolog subfamily A member 2

1

1

High-throughput

0.457

High

1036812

SQSTM
Sequestosome-1

1

1

High-throughput

0.457

High

1292544

SHLB1
Endophilin-B1

1

2

High-throughput

0.445

High

1292532

PININ
Pinin

1

0

High-throughput

0.438

High

472913

H2AB2
Histone H2A-Bbd type 2/3

1

3

High-throughput

0.437

High

908958

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

1075722

SF01
Splicing factor 1

1

0

High-throughput

0.426

High

1130442

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1292523

RB40C
Ras-related protein Rab-40C

1

1

High-throughput

0.417

High

68444

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

4

High-throughput

0.407

High

376294

ANXA1
Annexin A1

1

0

Small-scale

0.391

High

850292

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.279

Low

1077688

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.279

Low

1176054

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.279

Low

900796

RHOA
Transforming protein RhoA

1

0

High-throughput

0.249

Low

1243884

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

155808

UN13B
Protein unc-13 homolog B

1

0

High-throughput

0.238

Low

207587

CAH12
Carbonic anhydrase 12

1

0

High-throughput

0.238

Low

321616

AP2A1
AP-2 complex subunit alpha-1

1

0

High-throughput

0.238

Low

306271

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

0

High-throughput

0.232

Low

1241574

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024