Protein: TF65
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)

Gene: TF65, Rela
Organism: Mus musculus
Interactions: 98
UniProt ID: Q04207

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

638449

NFKB1
Nuclear factor NF-kappa-B p105 subunit

19

16

Small-scale

0.987

High

978991

IKBA
NF-kappa-B inhibitor alpha

21

20

Small-scale

0.986

High

978989

NFKB2
Nuclear factor NF-kappa-B p100 subunit

7

20

Small-scale

0.957

High

978962

IKBB
NF-kappa-B inhibitor beta

6

20

Small-scale

0.932

High

978958

TF65
Transcription factor p65

3

18

Small-scale

0.833

High

420397

TNFA
Tumor necrosis factor

14

15

Small-scale

0.757

High

978959

RELB
Transcription factor RelB

2

18

Small-scale

0.754

High

667791

NOS2
Nitric oxide synthase, inducible

12

3

Small-scale

0.754

High

439911

IL6
Interleukin-6

11

4

Small-scale

0.751

High

486360

CCL2
C-C motif chemokine 2

6

20

Small-scale

0.724

High

677067

CCL5
C-C motif chemokine 5

5

20

Small-scale

0.702

High

978970

PANKY
Photoreceptor ankyrin repeat protein

1

9

High-throughput

0.698

High

978978

ANKR7
Ankyrin repeat domain-containing protein 7

1

5

High-throughput

0.698

High

978979

IL23A
Interleukin-23 subunit alpha

4

3

Small-scale

0.683

High

70914

EP300
Histone acetyltransferase p300

4

15

Small-scale

0.677

High

796695

IL12B
Interleukin-12 subunit beta

4

6

Small-scale

0.676

High

799599

CBP
Histone lysine acetyltransferase CREBBP

3

15

Small-scale

0.675

High

546806

REL
Proto-oncogene c-Rel

1

18

Small-scale

0.646

High

489488

BCL2
Apoptosis regulator Bcl-2

3

4

Small-scale

0.640

High

500673

CXCL2
C-X-C motif chemokine 2

3

15

Small-scale

0.640

High

978976

ZDH13
Palmitoyltransferase ZDHHC13

1

4

High-throughput

0.625

High

404136

JUN
Transcription factor Jun

1

20

Small-scale

0.618

High

978992

FM1AA
Protein fem-1 homolog A-A

1

3

Small-scale

0.618

High

970122

CTNB1
Catenin beta-1

2

10

Small-scale

0.611

High

514300

NGAL
Neutrophil gelatinase-associated lipocalin

2

3

Small-scale

0.601

High

547396

IRF1
Interferon regulatory factor 1

2

20

Small-scale

0.598

High

222601

IKBE
NF-kappa-B inhibitor epsilon

1

20

Small-scale

0.590

High

348420

MYC
Myc proto-oncogene protein

2

13

Small-scale

0.584

High

499365

IL1B
Interleukin-1 beta

2

7

Small-scale

0.584

High

629213

CCND1
G1/S-specific cyclin-D1

2

4

Small-scale

0.584

High

648956

TNR5
Tumor necrosis factor receptor superfamily member 5

2

5

Small-scale

0.584

High

978961

TNAP3
Tumor necrosis factor alpha-induced protein 3

2

8

Small-scale

0.584

High

978974

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

7

Small-scale

0.584

High

978985

PIAS4
E3 SUMO-protein ligase PIAS4

2

7

Small-scale

0.584

High

978973

MED17
Mediator of RNA polymerase II transcription subunit 17

1

2

Small-scale

0.582

High

978971

MTA1
Metastasis-associated protein MTA1

1

3

Small-scale

0.561

High

978966

NR0B2
Nuclear receptor subfamily 0 group B member 2

1

7

Small-scale

0.554

High

101438

F8VPR5
histone acetyltransferase

1

15

Small-scale

0.552

High

533903

DNMT1
DNA

1

2

High-throughput

0.541

High

978972

ZMY11
Zinc finger MYND domain-containing protein 11

1

3

High-throughput

0.541

High

978977

CXXC1
CXXC-type zinc finger protein 1

1

3

High-throughput

0.541

High

978990

SRBP1
Sterol regulatory element-binding protein 1

1

15

High-throughput

0.541

High

140259

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.536

High

978969

NANOG
Homeobox protein NANOG

1

11

Small-scale

0.527

High

70600

BRPF1
Peregrin

1

0

High-throughput

0.518

High

978975

CERS2
Ceramide synthase 2

1

0

High-throughput

0.518

High

607548

MYD88
Myeloid differentiation primary response protein MyD88

1

1

Small-scale

0.515

High

973807

KPCZ
Protein kinase C zeta type

1

9

Small-scale

0.501

High

521440

NR4A1
Nuclear receptor subfamily 4 group A member 1

1

20

Small-scale

0.500

High

222295

PIAS3
E3 SUMO-protein ligase PIAS3

1

7

High-throughput

0.481

High

193348

SOCS1
Suppressor of cytokine signaling 1

1

9

Small-scale

0.479

High

223162

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

3

Small-scale

0.479

High

291456

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

17

Small-scale

0.479

High

292659

SP1
Transcription factor Sp1

1

10

Small-scale

0.479

High

292678

CCL20
C-C motif chemokine 20

1

20

Small-scale

0.479

High

356846

P53
Cellular tumor antigen p53

1

8

Small-scale

0.479

High

381343

IL2
Interleukin-2

1

6

Small-scale

0.479

High

421454

CSF1
Macrophage colony-stimulating factor 1

1

2

Small-scale

0.479

High

522399

GROA
Growth-regulated alpha protein

1

13

Small-scale

0.479

High

530230

ICAM1
Intercellular adhesion molecule 1

1

5

Small-scale

0.479

High

541497

HMOX1
Heme oxygenase 1

1

1

Small-scale

0.479

High

551458

RAG1
V(D)J recombination-activating protein 1

1

7

Small-scale

0.479

High

568050

CXL10
C-X-C motif chemokine 10

1

16

Small-scale

0.479

High

601121

RAG2
V(D)J recombination-activating protein 2

1

1

Small-scale

0.479

High

723510

HES1
Transcription factor HES-1

1

5

Small-scale

0.479

High

740714

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

Small-scale

0.479

High

740748

THB
Thyroid hormone receptor beta

1

20

Small-scale

0.479

High

796689

IL12A
Interleukin-12 subunit alpha

1

4

Small-scale

0.479

High

817042

IL15
Interleukin-15

1

1

Small-scale

0.479

High

846401

RORA
Nuclear receptor ROR-alpha

1

19

Small-scale

0.479

High

868930

ATX1
Ataxin-1

1

4

High-throughput

0.479

High

936384

HDAC2
Histone deacetylase 2

1

20

Small-scale

0.479

High

936591

GFI1
Zinc finger protein Gfi-1

1

1

Small-scale

0.479

High

956321

PSME2
Proteasome activator complex subunit 2

1

2

Small-scale

0.479

High

961580

LYAM2
E-selectin

1

3

Small-scale

0.479

High

978960

NR4A2
Nuclear receptor subfamily 4 group A member 2

1

20

Small-scale

0.479

High

978963

I17RA
Interleukin-17 receptor A

1

2

Small-scale

0.479

High

978964

E2F1
Transcription factor E2F1

1

2

Small-scale

0.479

High

978965

HS71A
Heat shock 70 kDa protein 1A

1

20

Small-scale

0.479

High

978967

SQSTM
Sequestosome-1

1

2

Small-scale

0.479

High

978982

KAT2A
Histone acetyltransferase KAT2A

1

5

Small-scale

0.479

High

978983

TBX21
T-box transcription factor TBX21

1

4

Small-scale

0.479

High

978993

HDAC6
Histone deacetylase 6

1

20

Small-scale

0.479

High

351497

NGF
Beta-nerve growth factor

1

0

Small-scale

0.458

High

456390

CSF3
Granulocyte colony-stimulating factor

1

0

Small-scale

0.458

High

660217

I23O1
Indoleamine 2,3-dioxygenase 1

1

0

Small-scale

0.458

High

978968

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

Small-scale

0.458

High

978980

HEPC
Hepcidin

1

0

Small-scale

0.458

High

978984

TREM1
Triggering receptor expressed on myeloid cells 1

1

0

Small-scale

0.458

High

978986

GLRX1
Glutaredoxin-1

1

0

Small-scale

0.458

High

978988

ENPP2
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

1

0

Small-scale

0.458

High

292411

HDAC3
Histone deacetylase 3

1

20

Small-scale

0.445

High

722764

RAB21
Ras-related protein Rab-21

1

1

High-throughput

0.445

High

978981

BRD4
Bromodomain-containing protein 4

1

4

Small-scale

0.445

High

352896

IFNB
Interferon beta

1

7

Small-scale

0.437

High

546354

IL9
Interleukin-9

1

2

Small-scale

0.437

High

978987

TLR2
Toll-like receptor 2

1

0

Small-scale

0.426

High


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Last updated: 15 Jul 2024