HitPredict

Interactor 1: B3KSH4 (B3KSH4)
Huntingtin interacting protein 2, isoform CRA_a (cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa)
Gene: HIP2

Interactor 2: HOIL1 (Q9BYM8)
RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (HBV-associated factor 4) (Heme-oxidized IRP2 ubiquitin ligase 1) (HOIL-1) (Hepatitis B virus X-associated protein 4) (RING finger protein 54) (RING-type E3 ubiquitin transferase HOIL-1) (Ubiquitin-conjugating enzyme 7-interacting protein 3)
Gene: RBCK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19549727
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 97 Hs			1 510
+	Hs
		896367 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		HOIL1_HUMAN (1-510): 0: 577: 100.00
+	Hs
		919847 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		HOIL1_HUMAN (1-510): 0: 577: 100.00
+	Hs
		895899 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		HOIL1_HUMAN (1-510): 0: 577: 100.00
+	Hs
		919891 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RNF14_HUMAN (242-478): 1.26e-68: 229: 18.99
+	Hs
		895968 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		ARI1_HUMAN (216-496): 1.87e-68: 231: 18.09
+	Hs
		895938 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		RNF14_HUMAN (242-478): 1.26e-68: 229: 18.99
+	Ce
		715114 UBC2_CAEEL (1-51): 5.95e-30: 105: 41.18		Q9XUS3_CAEEL (150-489): 1.62e-66: 221: 16.81
+	Hs
		312553 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		ARI2_HUMAN (243-496): 7.23e-65: 220: 19.85
+	Hs
		312528 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		ARI2_HUMAN (243-496): 7.23e-65: 220: 19.85
+	Hs
		919757 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RN19B_HUMAN (277-477): 1.57e-57: 205: 22.97
+	Hs
		919876 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RN19A_HUMAN (256-477): 5.57e-57: 205: 16.60
+	Hs
		895819 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		RN19B_HUMAN (277-477): 1.57e-57: 205: 22.97
+	Hs
		227031 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		919878 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RN216_HUMAN (235-497): 5.21e-52: 191: 19.13
+	Hs
		227093 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		895928 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		RN216_HUMAN (235-497): 5.21e-52: 191: 19.13
+	Hs
		227029 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		842098 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		R144A_HUMAN (279-476): 3.85e-28: 115: 20.98
+	Hs
		72136 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		R144A_HUMAN (279-476): 3.85e-28: 115: 20.98
+	Hs
		842104 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		R144A_HUMAN (279-476): 3.85e-28: 115: 20.98