Protein: UMPS
Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (ODC) (ODCase) (EC 4.1.1.23)]

Gene: UMPS, umps-1
Organism: Caenorhabditis elegans
Interactions: 21
UniProt ID: G5EDZ2

Gene Ontology (top 5):
GO:0002119 - nematode larval development
GO:0004588 - orotate phosphoribosyltransferase activity
GO:0004590 - orotidine-5'-phosphate decarboxylase activity
GO:0005737 - cytoplasm
GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

112175

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.518

High

112177

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.518

High

109064

G4RZC8
PID domain-containing protein

1

0

High-throughput

0.486

High

112180

LE756
Protein let-756

1

0

Small-scale

0.486

High

72219

A8WIR1
Ribosomal Protein, Small subunit

1

1

High-throughput

0.481

High

112171

G5EES2
Moesin/ezrin/radixin homolog 1

1

1

High-throughput

0.481

High

112187

Q9N415
Variant SH3 domain protein

1

2

High-throughput

0.464

High

112176

PLK1
Serine/threonine-protein kinase plk-1

1

0

High-throughput

0.458

High

109684

G5EBK3
Moesin/ezrin/radixin homolog 1

1

1

High-throughput

0.457

High

112172

O17218
Ribosomal Protein, Small subunit

1

1

High-throughput

0.457

High

112186

Q9N3S5
Tyrosine-protein kinase

1

1

High-throughput

0.439

High

112174

O44490
ELKS/RAB6-interacting/CAST family member 2

1

2

High-throughput

0.437

High

112185

Q8IAA6
Tyrosine-protein kinase

1

2

High-throughput

0.417

High

112173

O18180
Mitochondrial Ribosomal Protein, Large

1

0

High-throughput

0.282

High

112178

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.282

High

112181

Q18036
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.282

High

112182

Q18809
HAT C-terminal dimerisation domain-containing protein

1

0

High-throughput

0.282

High

112183

Q18869
BPI2 domain-containing protein

1

0

High-throughput

0.282

High

112184

Q22003
Cleft lip and palate transmembrane protein 1 homolog

1

0

High-throughput

0.282

High

112188

SPCS2
Signal peptidase complex subunit 2

1

0

High-throughput

0.282

High

112179

ACH2
Acetylcholine receptor subunit beta-type unc-29

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025