Protein: TYRO3
Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)

Gene: TYRO3
Organism: Homo sapiens
Interactions: 156
UniProt ID: Q06418

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0001764 - neuron migration
GO:0001779 - natural killer cell differentiation
GO:0004713 - protein tyrosine kinase activity
GO:0004714 - transmembrane receptor protein tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

924505

GRB2
Growth factor receptor-bound protein 2

3

20

High-throughput

0.858

High

987244

GAS6
Growth arrest-specific protein 6

2

20

Small-scale

0.812

High

987238

TYRO3
Tyrosine-protein kinase receptor TYRO3

2

19

Small-scale

0.778

High

655328

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

Small-scale

0.713

High

274206

STK16
Serine/threonine-protein kinase 16

1

16

High-throughput

0.691

High

985141

ACHB3
Neuronal acetylcholine receptor subunit beta-3

3

1

High-throughput

0.667

High

987272

LPAR1
Lysophosphatidic acid receptor 1

3

1

High-throughput

0.667

High

337441

ABL1
Tyrosine-protein kinase ABL1

1

20

High-throughput

0.646

High

382400

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

16

High-throughput

0.646

High

441490

MET
Hepatocyte growth factor receptor

1

19

High-throughput

0.646

High

530168

NCAM1
Neural cell adhesion molecule 1

1

18

High-throughput

0.646

High

545102

PVR
Poliovirus receptor

1

17

High-throughput

0.646

High

726168

BASI
Basigin

1

20

High-throughput

0.646

High

738533

TGFR1
TGF-beta receptor type-1

1

13

High-throughput

0.646

High

987242

PTK7
Inactive tyrosine-protein kinase 7

1

20

High-throughput

0.646

High

987256

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

1

20

High-throughput

0.646

High

987275

LRC59
Leucine-rich repeat-containing protein 59

1

20

High-throughput

0.646

High

987290

RAB1B
Ras-related protein Rab-1B

1

12

High-throughput

0.646

High

987249

CC50B
Cell cycle control protein 50B

2

6

High-throughput

0.628

High

383763

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.621

High

674403

UFO
Tyrosine-protein kinase receptor UFO

1

19

Small-scale

0.621

High

522932

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.618

High

665221

EPHA2
Ephrin type-A receptor 2

1

19

High-throughput

0.618

High

789061

ABL2
Tyrosine-protein kinase ABL2

1

20

High-throughput

0.618

High

987240

ARHG5
Rho guanine nucleotide exchange factor 5

1

20

High-throughput

0.618

High

987281

COCA1

1

17

High-throughput

0.618

High

987310

M4K5
Mitogen-activated protein kinase kinase kinase kinase 5

1

20

High-throughput

0.618

High

642044

KRA59
Keratin-associated protein 5-9

3

15

High-throughput

0.613

High

987293

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.602

High

431770

HS90A
Heat shock protein HSP 90-alpha

2

20

High-throughput

0.594

High

438100

HS90B
Heat shock protein HSP 90-beta

2

20

High-throughput

0.594

High

987282

MDFI
MyoD family inhibitor

1

1

High-throughput

0.573

High

987315

NEMO
NF-kappa-B essential modulator

1

15

High-throughput

0.561

High

987267

LNX1
E3 ubiquitin-protein ligase LNX

1

20

Small-scale

0.555

High

70761

VWC2L
von Willebrand factor C domain-containing protein 2-like

2

6

High-throughput

0.553

High

987286

KRA92
Keratin-associated protein 9-2

2

6

High-throughput

0.553

High

987307

ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

1

19

High-throughput

0.553

High

987288

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

10

High-throughput

0.541

High

987246

TNIP1
TNFAIP3-interacting protein 1

2

20

High-throughput

0.539

High

654279

CALX
Calnexin

1

20

High-throughput

0.536

High

987268

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

5

High-throughput

0.536

High

987274

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.536

High

987313

SRPRB
Signal recognition particle receptor subunit beta

1

20

High-throughput

0.536

High

889232

KR107
Keratin-associated protein 10-7

1

20

High-throughput

0.523

High

889457

KR108
Keratin-associated protein 10-8

1

14

High-throughput

0.523

High

889749

KR109
Keratin-associated protein 10-9

1

16

High-throughput

0.523

High

987257

K1C40
Keratin, type I cytoskeletal 40

1

8

High-throughput

0.523

High

987287

KRA42
Keratin-associated protein 4-2

1

6

High-throughput

0.523

High

987312

KLK4
Kallikrein-4

1

20

High-throughput

0.523

High

987266

SUV3
ATP-dependent RNA helicase SUPV3L1, mitochondrial

1

0

High-throughput

0.513

High

118283

HAX1
HCLS1-associated protein X-1

1

2

High-throughput

0.500

High

161056

CLGN
Calmegin

1

20

High-throughput

0.500

High

162657

XPO1
Exportin-1

1

15

High-throughput

0.500

High

280243

CBPD
Carboxypeptidase D

1

12

High-throughput

0.500

High

299883

ERLN2
Erlin-2

1

8

High-throughput

0.500

High

364252

TFR1
Transferrin receptor protein 1

1

6

High-throughput

0.500

High

390192

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

6

High-throughput

0.500

High

390843

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

6

High-throughput

0.500

High

393175

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

2

High-throughput

0.500

High

394590

A4
Amyloid-beta precursor protein

1

17

High-throughput

0.500

High

397351

ADT2
ADP/ATP translocase 2

1

6

High-throughput

0.500

High

437340

4F2
Amino acid transporter heavy chain SLC3A2

1

3

High-throughput

0.500

High

500776

CLUS
Clusterin

1

6

High-throughput

0.500

High

502009

BIP
Endoplasmic reticulum chaperone BiP

1

20

High-throughput

0.500

High

506983

LAMP1
Lysosome-associated membrane glycoprotein 1

1

7

High-throughput

0.500

High

514826

MPRI
Cation-independent mannose-6-phosphate receptor

1

12

High-throughput

0.500

High

518325

ADT3
ADP/ATP translocase 3

1

6

High-throughput

0.500

High

531806

PDIA4
Protein disulfide-isomerase A4

1

20

High-throughput

0.500

High

561560

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

3

High-throughput

0.500

High

580227

CADH2
Cadherin-2

1

20

High-throughput

0.500

High

588592

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

6

High-throughput

0.500

High

594683

MPRD
Cation-dependent mannose-6-phosphate receptor

1

2

High-throughput

0.500

High

681414

DNJA1
DnaJ homolog subfamily A member 1

1

20

High-throughput

0.500

High

716663

CTNA1
Catenin alpha-1

1

12

High-throughput

0.500

High

717022

CTNB1
Catenin beta-1

1

20

High-throughput

0.500

High

762964

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

5

High-throughput

0.500

High

792703

EAA1
Excitatory amino acid transporter 1

1

10

High-throughput

0.500

High

795108

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.500

High

809899

STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

5

High-throughput

0.500

High

815980

ATPO
ATP synthase subunit O, mitochondrial

1

2

High-throughput

0.500

High

838787

EMD
Emerin

1

14

High-throughput

0.500

High

872013

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

1

High-throughput

0.500

High

901460

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

7

High-throughput

0.500

High

944199

PRKDC
DNA-dependent protein kinase catalytic subunit

1

18

High-throughput

0.500

High

959191

S25A3
Solute carrier family 25 member 3

1

9

High-throughput

0.500

High

966685

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

13

High-throughput

0.500

High

987245

DSC3
Desmocollin-3

1

20

High-throughput

0.500

High

987247

OZF
Zinc finger protein OZF

1

7

High-throughput

0.500

High

987252

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

7

High-throughput

0.500

High

987253

NU188
Nucleoporin NUP188

1

2

High-throughput

0.500

High

987254

ATD3B
ATPase family AAA domain-containing protein 3B

1

7

High-throughput

0.500

High

987255

SE1L2
Protein sel-1 homolog 2

1

10

High-throughput

0.500

High

987259

CNNM4
Metal transporter CNNM4

1

5

High-throughput

0.500

High

987262

QSOX2
Sulfhydryl oxidase 2

1

20

High-throughput

0.500

High

987265

PLD3
5'-3' exonuclease PLD3

1

1

High-throughput

0.500

High

987269

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

1

2

High-throughput

0.500

High

987271

S39A7
Zinc transporter SLC39A7

1

5

High-throughput

0.500

High

987283

NTPCR
Cancer-related nucleoside-triphosphatase

1

12

High-throughput

0.500

High

987284

TBB6
Tubulin beta-6 chain

1

12

High-throughput

0.500

High

987289

MAGT1
Magnesium transporter protein 1

1

2

High-throughput

0.500

High

987291

TMX1
Thioredoxin-related transmembrane protein 1

1

20

High-throughput

0.500

High

987298

T106B
Transmembrane protein 106B

1

5

High-throughput

0.500

High

987300

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

1

High-throughput

0.500

High

987302

TECR
Very-long-chain enoyl-CoA reductase

1

4

High-throughput

0.500

High

987303

HACD3
Very-long-chain

1

8

High-throughput

0.500

High

987305

DJB11
DnaJ homolog subfamily B member 11

1

20

High-throughput

0.500

High

987306

DDX20
Probable ATP-dependent RNA helicase DDX20

1

5

High-throughput

0.500

High

987308

ITM2B
Integral membrane protein 2B

1

6

High-throughput

0.500

High

987311

HYOU1
Hypoxia up-regulated protein 1

1

20

High-throughput

0.500

High

149981

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

1

10

High-throughput

0.494

High

361478

APOE
Apolipoprotein E

1

5

High-throughput

0.481

High

821550

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.479

High

987264

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

0

High-throughput

0.479

High

987279

NEUR1
Sialidase-1

1

0

High-throughput

0.479

High

987314

CEPT1
Choline/ethanolaminephosphotransferase 1

1

0

High-throughput

0.479

High

264038

TACC1
Transforming acidic coiled-coil-containing protein 1

1

20

High-throughput

0.479

High

438749

SRPRA
Signal recognition particle receptor subunit alpha

1

11

High-throughput

0.479

High

444721

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

10

High-throughput

0.479

High

987239

CKAP4
Cytoskeleton-associated protein 4

1

20

High-throughput

0.479

High

987243

STIM1
Stromal interaction molecule 1

1

15

High-throughput

0.479

High

987261

NFXL1
NF-X1-type zinc finger protein NFXL1

1

20

High-throughput

0.479

High

987273

US6NL
USP6 N-terminal-like protein

1

12

High-throughput

0.479

High

987276

DDRGK
DDRGK domain-containing protein 1

1

6

High-throughput

0.479

High

987278

CLCC1
Chloride channel CLIC-like protein 1

1

9

High-throughput

0.479

High

987294

GORS2
Golgi reassembly-stacking protein 2

1

13

High-throughput

0.479

High

987296

JPH1
Junctophilin-1

1

10

High-throughput

0.479

High

987304

STIM2
Stromal interaction molecule 2

1

15

High-throughput

0.479

High

987309

CHTOP
Chromatin target of PRMT1 protein

1

5

High-throughput

0.479

High

653148

DCK
Deoxycytidine kinase

1

0

High-throughput

0.458

High

987277

RANB9
Ran-binding protein 9

1

9

Small-scale

0.457

High

987297

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

130490

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

9

High-throughput

0.457

High

203029

COCH
Cochlin

1

3

High-throughput

0.457

High

207929

XPOT
Exportin-T

1

14

High-throughput

0.457

High

296902

LTN1
E3 ubiquitin-protein ligase listerin

1

2

High-throughput

0.457

High

413088

AGAL
Alpha-galactosidase A

1

4

High-throughput

0.457

High

735929

ATPG
ATP synthase subunit gamma, mitochondrial

1

2

High-throughput

0.457

High

987241

DNJC3
DnaJ homolog subfamily C member 3

1

20

High-throughput

0.457

High

987248

CDC37
Hsp90 co-chaperone Cdc37

1

20

High-throughput

0.457

High

987251

GXLT1
Glucoside xylosyltransferase 1

1

3

High-throughput

0.457

High

987258

SFXN4
Sideroflexin-4

1

1

High-throughput

0.457

High

987263

MON2
Protein MON2 homolog

1

9

High-throughput

0.457

High

987270

FACR1
Fatty acyl-CoA reductase 1

1

3

High-throughput

0.457

High

987292

RNF41
E3 ubiquitin-protein ligase NRDP1

1

17

High-throughput

0.457

High

987295

TM9S3
Transmembrane 9 superfamily member 3

1

3

High-throughput

0.457

High

987299

FANCI
Fanconi anemia group I protein

1

7

High-throughput

0.457

High

239956

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

11

High-throughput

0.445

High

344486

A2MG
Alpha-2-macroglobulin

1

3

High-throughput

0.439

High

888853

KR103
Keratin-associated protein 10-3

1

14

High-throughput

0.439

High

987260

F171B
Protein FAM171B

1

17

High-throughput

0.437

High

987280

CDCA3
Cell division cycle-associated protein 3

1

10

High-throughput

0.437

High

987285

RFIP5
Rab11 family-interacting protein 5

1

7

High-throughput

0.437

High

847254

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.261

Low

987250

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

987301

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024