Protein: IRF3
Interferon regulatory factor 3 (IRF-3)

Gene: IRF3
Organism: Mus musculus
Interactions: 26
UniProt ID: P70671

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001819 - positive regulation of cytokine production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

936895

IRF3
Interferon regulatory factor 3

4

15

Small-scale

0.873

High

352893

IFNB
Interferon beta

6

20

Small-scale

0.721

High

70908

EP300
Histone acetyltransferase p300

1

17

Small-scale

0.618

High

936631

TANK
TRAF family member-associated NF-kappa-B activator

2

2

Small-scale

0.584

High

936907

TBK1
Serine/threonine-protein kinase TBK1

1

14

Small-scale

0.561

High

936905

ZBP1
Z-DNA-binding protein 1

2

0

Small-scale

0.559

High

515223

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

0

Small-scale

0.554

High

936901

RNF41
E3 ubiquitin-protein ligase NRDP1

1

20

Small-scale

0.515

High

251074

TRI18
E3 ubiquitin-protein ligase Midline-1

1

15

Small-scale

0.479

High

427402

IFNA4
Interferon alpha-4

1

20

Small-scale

0.479

High

432423

HS90A
Heat shock protein HSP 90-alpha

1

7

Small-scale

0.479

High

513671

HS90B
Heat shock protein HSP 90-beta

1

7

Small-scale

0.479

High

541496

HMOX1
Heme oxygenase 1

1

1

Small-scale

0.479

High

928244

SUMO1
Small ubiquitin-related modifier 1

1

6

Small-scale

0.479

High

936460

PITX1
Pituitary homeobox 1

1

1

Small-scale

0.479

High

936897

NCOA2
Nuclear receptor coactivator 2

1

2

Small-scale

0.479

High

936898

ISG15
Ubiquitin-like protein ISG15

1

10

Small-scale

0.479

High

936899

RIGI
Antiviral innate immune response receptor RIG-I

1

7

High-throughput

0.479

High

936900

TCAM1
TIR domain-containing adapter molecule 1

1

5

Small-scale

0.479

High

936903

TRI26
Tripartite motif-containing protein 26

1

10

Small-scale

0.479

High

936904

IL23A
Interleukin-23 subunit alpha

1

2

Small-scale

0.479

High

936906

UBP18
Ubl carboxyl-terminal hydrolase 18

1

2

Small-scale

0.479

High

936908

SUMO3
Small ubiquitin-related modifier 3

1

6

Small-scale

0.479

High

936896

I12R1
Interleukin-12 receptor subunit beta-1

1

3

Small-scale

0.437

High

936902

GRIP1
Glutamate receptor-interacting protein 1

1

2

Small-scale

0.437

High


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Last updated: 15 Jul 2024