Protein: HIF1A
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein)

Gene: HIF1A
Organism: Mus musculus
Interactions: 34
UniProt ID: Q61221

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000302 - response to reactive oxygen species
GO:0000791 - euchromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

864794

ARNT
Aryl hydrocarbon receptor nuclear translocator

5

20

Small-scale

0.934

High

772240

VHL
von Hippel-Lindau disease tumor suppressor

5

8

Small-scale

0.922

High

1142409

BMAL1
Basic helix-loop-helix ARNT-like protein 1

2

19

Small-scale

0.754

High

627472

NECD
Necdin

2

15

Small-scale

0.628

High

70923

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.618

High

348427

MYC
Myc proto-oncogene protein

1

9

Small-scale

0.618

High

1012216

HIF3A
Hypoxia-inducible factor 3-alpha

1

17

Small-scale

0.618

High

1142404

EGLN3
Prolyl hydroxylase EGLN3

1

14

Small-scale

0.618

High

1142405

EGLN2
Prolyl hydroxylase EGLN2

1

14

Small-scale

0.618

High

1142406

EGLN1
Egl nine homolog 1

1

14

Small-scale

0.618

High

223183

TLX3
T-cell leukemia homeobox protein 3

1

12

High-throughput

0.541

High

725296

FOXA2
Hepatocyte nuclear factor 3-beta

1

13

Small-scale

0.536

High

1142399

TSG10
Testis-specific gene 10 protein

1

9

Small-scale

0.506

High

886457

SENP1
Sentrin-specific protease 1

1

1

Small-scale

0.501

High

930489

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.501

High

968961

SNAI1
Zinc finger protein SNAI1

1

2

Small-scale

0.501

High

432431

HS90A
Heat shock protein HSP 90-alpha

1

17

Small-scale

0.479

High

571858

HS71B
Heat shock 70 kDa protein 1B

1

9

Small-scale

0.479

High

667795

NOS2
Nitric oxide synthase, inducible

1

1

Small-scale

0.479

High

846435

RORG
Nuclear receptor ROR-gamma

1

20

Small-scale

0.479

High

854529

KPYM
Pyruvate kinase PKM

1

3

Small-scale

0.479

High

928248

SUMO1
Small ubiquitin-related modifier 1

1

3

Small-scale

0.479

High

990981

MTF1
Metal regulatory transcription factor 1

1

1

Small-scale

0.479

High

1123406

E2F8
Transcription factor E2F8

1

5

Small-scale

0.479

High

1142400

RFOX3
RNA binding protein fox-1 homolog 3

1

2

Small-scale

0.479

High

1142401

SMAD3
Mothers against decapentaplegic homolog 3

1

8

Small-scale

0.479

High

1142402

HDAC7
Histone deacetylase 7

1

11

Small-scale

0.479

High

1142403

KAT5
Histone acetyltransferase KAT5

1

3

Small-scale

0.479

High

1142407

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

2

Small-scale

0.479

High

1142410

FOXO3
Forkhead box protein O3

1

18

Small-scale

0.479

High

984750

PGH2
Prostaglandin G/H synthase 2

1

0

Small-scale

0.458

High

987631

ATF4
Cyclic AMP-dependent transcription factor ATF-4

1

0

Small-scale

0.458

High

554910

KPCE
Protein kinase C epsilon type

1

6

Small-scale

0.445

High

1142408

CP2S1
Cytochrome P450 2S1

1

1

Small-scale

0.437

High


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Last updated: 15 Jul 2024