Protein: RFC2
Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40)

Gene: RFC2
Organism: Homo sapiens
Interactions: 153
UniProt ID: P35250

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003689 - DNA clamp loader activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

721933

RFC4
Replication factor C subunit 4

9

16

Small-scale

0.967

High

722071

RFC5
Replication factor C subunit 5

7

16

Small-scale

0.956

High

517100

PCNA
Proliferating cell nuclear antigen

6

12

Small-scale

0.946

High

722068

RFC1
Replication factor C subunit 1

3

17

Small-scale

0.817

High

637337

PSA1
Proteasome subunit alpha type-1

2

1

High-throughput

0.783

High

226671

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.754

High

722134

CTF18
Chromosome transmission fidelity protein 18 homolog

1

17

Small-scale

0.724

High

279000

RAD17
Cell cycle checkpoint protein RAD17

5

20

Small-scale

0.721

High

244022

BRD4
Bromodomain-containing protein 4

4

10

Small-scale

0.698

High

650502

RFA1
Replication protein A 70 kDa DNA-binding subunit

4

3

Small-scale

0.676

High

722148

DCC1
Sister chromatid cohesion protein DCC1

3

7

High-throughput

0.667

High

346081

MYC
Myc proto-oncogene protein

3

3

High-throughput

0.656

High

719811

RFA3
Replication protein A 14 kDa subunit

3

3

High-throughput

0.656

High

552072

RFA2
Replication protein A 32 kDa subunit

3

5

High-throughput

0.640

High

475409

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.618

High

722072

RFC3
Replication factor C subunit 3

1

16

High-throughput

0.618

High

722083

RD23B
UV excision repair protein RAD23 homolog B

1

2

High-throughput

0.618

High

455149

PARP1
Poly [ADP-ribose] polymerase 1

2

11

High-throughput

0.611

High

722116

ZIC1
Zinc finger protein ZIC 1

2

1

High-throughput

0.606

High

722070

BRCA1
Breast cancer type 1 susceptibility protein

2

2

High-throughput

0.584

High

722088

H4
Histone H4

2

7

High-throughput

0.584

High

722090

H31
Histone H3.1

2

13

High-throughput

0.584

High

722114

BRD3
Bromodomain-containing protein 3

2

13

High-throughput

0.584

High

722119

IF16
Gamma-interferon-inducible protein 16

2

2

High-throughput

0.584

High

722162

MCM9
DNA helicase MCM9

2

4

Small-scale

0.584

High

722121

OTU1
Ubiquitin thioesterase OTU1

2

0

High-throughput

0.580

High

369089

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

722136

ESR2
Estrogen receptor beta

2

6

High-throughput

0.571

High

71077

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

1

High-throughput

0.536

High

133346

NOP56
Nucleolar protein 56

1

3

High-throughput

0.536

High

245883

HUS1
Checkpoint protein HUS1

1

2

High-throughput

0.536

High

417987

NPM
Nucleophosmin

1

3

High-throughput

0.536

High

528668

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

564817

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.536

High

649335

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.536

High

722074

KSYK
Tyrosine-protein kinase SYK

1

5

High-throughput

0.536

High

722086

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.536

High

722093

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

3

High-throughput

0.536

High

722095

SSRP1
FACT complex subunit SSRP1

1

11

High-throughput

0.536

High

722105

CUL3
Cullin-3

1

4

High-throughput

0.536

High

722120

H2B2E
Histone H2B type 2-E

1

14

High-throughput

0.536

High

722128

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

722130

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

722137

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.536

High

722142

TCPQM
T-complex protein 1 subunit theta-like 2

1

4

High-throughput

0.536

High

722144

RAD9A
Cell cycle checkpoint control protein RAD9A

1

3

High-throughput

0.536

High

722159

TF7L2
Transcription factor 7-like 2

1

11

High-throughput

0.536

High

722165

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.536

High

536482

IRF2
Interferon regulatory factor 2

1

0

High-throughput

0.513

High

722172

EXOS1
Exosome complex component CSL4

1

0

High-throughput

0.513

High

722085

SUMO2
Small ubiquitin-related modifier 2

1

3

High-throughput

0.501

High

722161

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

Small-scale

0.480

High

122522

MEN1
Menin

1

3

High-throughput

0.479

High

125190

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.479

High

148457

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

150885

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

1

High-throughput

0.479

High

179561

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

4

High-throughput

0.479

High

233247

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

294451

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.479

High

317918

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

6

High-throughput

0.479

High

373787

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

391576

H2A1B
Histone H2A type 1-B/E

1

7

High-throughput

0.479

High

441906

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.479

High

622373

CCND1
G1/S-specific cyclin-D1

1

2

High-throughput

0.479

High

631360

BRD2
Bromodomain-containing protein 2

1

16

High-throughput

0.479

High

707536

H2B1B
Histone H2B type 1-B

1

14

High-throughput

0.479

High

718546

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

722069

T2FA
General transcription factor IIF subunit 1

1

1

High-throughput

0.479

High

722073

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

722075

GATA4
Transcription factor GATA-4

1

1

High-throughput

0.479

High

722076

NKX21
Homeobox protein Nkx-2.1

1

4

High-throughput

0.479

High

722077

SOX2
Transcription factor SOX-2

1

11

High-throughput

0.479

High

722078

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.479

High

722079

CENPA
Histone H3-like centromeric protein A

1

13

High-throughput

0.479

High

722081

PMS1
PMS1 protein homolog 1

1

2

High-throughput

0.479

High

722082

PMS2
Mismatch repair endonuclease PMS2

1

2

High-throughput

0.479

High

722087

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

722091

H33
Histone H3.3

1

13

High-throughput

0.479

High

722092

VIGLN
Vigilin

1

4

High-throughput

0.479

High

722094

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

High-throughput

0.479

High

722096

EP300
Histone acetyltransferase p300

1

12

High-throughput

0.479

High

722097

TP53B
TP53-binding protein 1

1

3

High-throughput

0.479

High

722098

NFX1
Transcriptional repressor NF-X1

1

2

High-throughput

0.479

High

722099

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.479

High

722101

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

6

High-throughput

0.479

High

722102

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

722103

SNW1
SNW domain-containing protein 1

1

3

High-throughput

0.479

High

722104

CUL1
Cullin-1

1

4

Small-scale

0.479

High

722107

HLTF
Helicase-like transcription factor

1

7

High-throughput

0.479

High

722109

MDC1
Mediator of DNA damage checkpoint protein 1

1

5

High-throughput

0.479

High

722111

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

Small-scale

0.479

High

722112

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

722113

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

722115

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.479

High

722118

HIF1A
Hypoxia-inducible factor 1-alpha

1

4

High-throughput

0.479

High

722122

IFIX
Pyrin and HIN domain-containing protein 1

1

2

High-throughput

0.479

High

722124

PAXI1
PAX-interacting protein 1

1

8

High-throughput

0.479

High

722125

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.479

High

722127

SETD3
Actin-histidine N-methyltransferase

1

1

High-throughput

0.479

High

722129

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

1

1

Small-scale

0.479

High

722133

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

722135

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

722143

CDC5L
Cell division cycle 5-like protein

1

3

High-throughput

0.479

High

722145

PITX2
Pituitary homeobox 2

1

3

High-throughput

0.479

High

722146

BARD1
BRCA1-associated RING domain protein 1

1

4

High-throughput

0.479

High

722147

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

5

High-throughput

0.479

High

722149

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

3

Small-scale

0.479

High

722150

FACD2
Fanconi anemia group D2 protein

1

7

High-throughput

0.479

High

722151

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

722152

SPRTN
DNA-dependent metalloprotease SPRTN

1

3

High-throughput

0.479

High

722153

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

722154

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

5

High-throughput

0.479

High

722156

ECT2
Protein ECT2

1

3

High-throughput

0.479

High

722158

BRD7
Bromodomain-containing protein 7

1

12

High-throughput

0.479

High

722160

ANLN
Anillin

1

3

High-throughput

0.479

High

722163

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

722164

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.479

High

722166

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

722168

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.479

High

722170

CE164
Centrosomal protein of 164 kDa

1

4

High-throughput

0.479

High

722173

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

722175

MAFB
Transcription factor MafB

1

7

High-throughput

0.479

High

722171

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

3

High-throughput

0.470

High

359709

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

599776

5NTD
5'-nucleotidase

1

0

High-throughput

0.458

High

722100

SKP2
S-phase kinase-associated protein 2

1

0

Small-scale

0.458

High

722108

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

722117

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

722126

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

722138

DDX11
ATP-dependent DNA helicase DDX11

1

0

Small-scale

0.458

High

722139

CDCA5
Sororin

1

0

High-throughput

0.458

High

722176

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.458

High

256949

KDM4A
Lysine-specific demethylase 4A

1

6

Small-scale

0.445

High

401516

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

496434

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

722110

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.445

High

722131

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.445

High

722157

LN28A
Protein lin-28 homolog A

1

2

High-throughput

0.445

High

722089

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.437

High

722106

TRI29
Tripartite motif-containing protein 29

1

4

Small-scale

0.437

High

722123

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

722140

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.437

High

722155

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

722167

HECD1
E3 ubiquitin-protein ligase HECTD1

1

7

High-throughput

0.437

High

722169

LIMC1
LIM and calponin homology domains-containing protein 1

1

2

High-throughput

0.437

High

722174

PHLA3
Pleckstrin homology-like domain family A member 3

1

1

High-throughput

0.437

High

722141

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

722080

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.408

High

722084

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

2

High-throughput

0.407

High

159910

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

0

High-throughput

0.316

High

498223

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

0

Small-scale

0.313

High

306764

VAMP5
Vesicle-associated membrane protein 5

1

0

High-throughput

0.279

Low

722132

CEP76
Centrosomal protein of 76 kDa

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024