Protein: COASY
Bifunctional coenzyme A synthase (CoA synthase) (NBP) (POV-2) [Includes: Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (DPCOAK)]

Gene: COASY
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q13057

Gene Ontology (top 5):
GO:0004140 - dephospho-CoA kinase activity
GO:0004595 - pantetheine-phosphate adenylyltransferase activity
GO:0005524 - ATP binding
GO:0005741 - mitochondrial outer membrane
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

616706

KS6B1
Ribosomal protein S6 kinase beta-1

1

2

Small-scale

0.589

High

470367

H2A1
Histone H2A type 1

2

0

High-throughput

0.585

High

572353

LEG3
Galectin-3

2

0

High-throughput

0.585

High

648495

CALL3
Calmodulin-like protein 3

2

0

High-throughput

0.585

High

1023395

LRC15
Leucine-rich repeat-containing protein 15

2

0

High-throughput

0.585

High

227320

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

1023379

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

1

High-throughput

0.571

High

304955

DUS14
Dual specificity protein phosphatase 14

2

1

High-throughput

0.558

High

1023398

TCPQM
T-complex protein 1 subunit theta-like 2

1

2

High-throughput

0.536

High

529057

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

806505

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

932970

ACTS
Actin, alpha skeletal muscle

1

0

High-throughput

0.513

High

1023371

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1023383

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

0

High-throughput

0.513

High

1023401

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

433735

LYN
Tyrosine-protein kinase Lyn

1

2

Small-scale

0.501

High

522948

SRC
Proto-oncogene tyrosine-protein kinase Src

1

2

Small-scale

0.501

High

796557

KSYK
Tyrosine-protein kinase SYK

1

1

Small-scale

0.501

High

986369

BTK
Tyrosine-protein kinase BTK

1

2

Small-scale

0.501

High

282215

SEGN
Secretagogin

1

1

High-throughput

0.489

High

1023397

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.489

High

1023400

KCD14
BTB/POZ domain-containing protein KCTD14

1

1

High-throughput

0.489

High

1023402

DNAI2
Dynein axonemal intermediate chain 2

1

1

High-throughput

0.489

High

394633

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1023407

KS6B2
Ribosomal protein S6 kinase beta-2

1

2

Small-scale

0.479

High

820901

PRC2A
Protein PRRC2A

1

0

High-throughput

0.458

High

915644

RHOB
Rho-related GTP-binding protein RhoB

1

0

High-throughput

0.458

High

923660

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

969661

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

1023377

FSCN1
Fascin

1

0

High-throughput

0.458

High

552610

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

651083

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

720347

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1023385

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1023411

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

Small-scale

0.437

High

217875

PRKY
Putative serine/threonine-protein kinase PRKY

1

0

High-throughput

0.426

High

581703

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.426

High

1023388

CNTRB
Centrobin

2

0

High-throughput

0.335

High

707364

S10A3
Protein S100-A3

2

0

High-throughput

0.318

High

1023380

HPHL1
Ferroxidase HEPHL1

2

0

High-throughput

0.318

High

1023386

DSG4
Desmoglein-4

2

0

High-throughput

0.318

High

1023387

MIB1
E3 ubiquitin-protein ligase MIB1

2

0

High-throughput

0.313

High

1023392

K1958
Uncharacterized protein KIAA1958

1

0

High-throughput

0.299

High

985947

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

0

Small-scale

0.292

High

729021

K1C20
Keratin, type I cytoskeletal 20

1

0

High-throughput

0.282

High

71111

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.279

Low

127775

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.279

Low

149855

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.279

Low

203449

MTG8R
Protein CBFA2T2

1

0

High-throughput

0.279

Low

276238

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.279

Low

278604

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.279

Low

328212

LGI1
Leucine-rich glioma-inactivated protein 1

1

0

High-throughput

0.279

Low

898007

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.279

Low

1023375

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

High-throughput

0.279

Low

1023376

SSX2
Protein SSX2

1

0

High-throughput

0.279

Low

1023382

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.279

Low

1023389

CLASR
CLK4-associating serine/arginine rich protein

1

0

High-throughput

0.279

Low

1023393

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

0

High-throughput

0.279

Low

1023399

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.279

Low

1023404

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

0

High-throughput

0.279

Low

1023405

CENPM
Centromere protein M

1

0

High-throughput

0.279

Low

1023410

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.279

Low

1023412

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

0

High-throughput

0.279

Low

1023394

PJA1
E3 ubiquitin-protein ligase Praja-1

1

0

Small-scale

0.261

Low

324367

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.249

Low

473391

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.249

Low

779331

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

903184

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

1023372

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

1023373

PKP1
Plakophilin-1

1

0

High-throughput

0.249

Low

1023374

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.249

Low

1023378

DJC21
DnaJ homolog subfamily C member 21

1

0

High-throughput

0.249

Low

1023381

EDC4
Enhancer of mRNA-decapping protein 4

1

0

Small-scale

0.249

Low

1023384

MIC27
MICOS complex subunit MIC27

1

0

High-throughput

0.249

Low

1023390

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.249

Low

1023391

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

1023396

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.249

Low

1023403

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1023406

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

1023408

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.249

Low

1023409

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1023413

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

484278

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024