Protein: KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)

Gene: KCC2G, CAMK2G
Organism: Homo sapiens
Interactions: 190
UniProt ID: Q13555

Gene Ontology (top 5):
GO:0004683 - calmodulin-dependent protein kinase activity
GO:0004723 - calcium-dependent protein serine/threonine phosphatase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1038957

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

8

16

Small-scale

0.971

High

1039048

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

7

16

High-throughput

0.964

High

1038863

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

4

18

High-throughput

0.902

High

1039035

ANLN
Anillin

3

2

High-throughput

0.847

High

1038977

RHG29
Rho GTPase-activating protein 29

3

5

High-throughput

0.839

High

1034842

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

2

5

High-throughput

0.811

High

1039027

RBM42
RNA-binding protein 42

2

3

High-throughput

0.811

High

874367

RAD
GTP-binding protein RAD

2

2

Small-scale

0.799

High

1038956

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

2

15

Small-scale

0.799

High

155570

TNPO2
Transportin-2

2

3

High-throughput

0.783

High

1038971

CDC37
Hsp90 co-chaperone Cdc37

2

4

High-throughput

0.783

High

1038983

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

4

High-throughput

0.783

High

787157

RHG25
Rho GTPase-activating protein 25

3

5

High-throughput

0.731

High

201330

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

4

Small-scale

0.724

High

1038992

CK2N1
Calcium/calmodulin-dependent protein kinase II inhibitor 1

2

6

High-throughput

0.705

High

433348

YES
Tyrosine-protein kinase Yes

1

12

High-throughput

0.691

High

550382

ZEP1
Zinc finger protein 40

1

3

High-throughput

0.691

High

672113

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

2

High-throughput

0.691

High

681178

ZEP2
Transcription factor HIVEP2

1

3

High-throughput

0.691

High

1038966

MELK
Maternal embryonic leucine zipper kinase

1

11

High-throughput

0.691

High

1038985

PKN3
Serine/threonine-protein kinase N3

1

10

High-throughput

0.691

High

1039021

CK2N2
Calcium/calmodulin-dependent protein kinase II inhibitor 2

1

6

High-throughput

0.691

High

1039034

PAK6
Serine/threonine-protein kinase PAK 6

1

9

High-throughput

0.691

High

1039046

CILK1
Serine/threonine-protein kinase ICK

1

14

High-throughput

0.691

High

885999

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

3

1

High-throughput

0.667

High

438147

HS90B
Heat shock protein HSP 90-beta

1

15

High-throughput

0.665

High

1038964

ITPR3
Inositol 1,4,5-trisphosphate receptor type 3

2

11

High-throughput

0.628

High

71116

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

5

High-throughput

0.618

High

648497

CALL3
Calmodulin-like protein 3

1

20

High-throughput

0.618

High

1038967

SLMAP
Sarcolemmal membrane-associated protein

1

1

High-throughput

0.618

High

1039015

CALL4
Calmodulin-like protein 4

1

20

High-throughput

0.618

High

431826

HS90A
Heat shock protein HSP 90-alpha

1

15

High-throughput

0.618

High

897048

ACTZ
Alpha-centractin

1

7

High-throughput

0.618

High

1036548

SQSTM
Sequestosome-1

1

5

Small-scale

0.618

High

1038988

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.618

High

1039029

KPCD2
Serine/threonine-protein kinase D2

1

18

High-throughput

0.618

High

1039032

PKHA4
Pleckstrin homology domain-containing family A member 4

1

16

High-throughput

0.618

High

1039033

MYO10
Unconventional myosin-X

1

2

Small-scale

0.618

High

1039049

NINL
Ninein-like protein

1

4

High-throughput

0.618

High

1039053

RBM8A
RNA-binding protein 8A

1

3

High-throughput

0.618

High

844046

FXR2
RNA-binding protein FXR2

2

18

High-throughput

0.614

High

377306

GCR
Glucocorticoid receptor

2

10

High-throughput

0.611

High

851928

NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

3

2

High-throughput

0.609

High

594524

PSB1
Proteasome subunit beta type-1

2

1

High-throughput

0.606

High

903809

NTF2
Nuclear transport factor 2

2

1

High-throughput

0.606

High

914646

ERR3
Estrogen-related receptor gamma

2

10

High-throughput

0.606

High

1038975

KRA61
Keratin-associated protein 6-1

2

1

High-throughput

0.606

High

1038991

KR193
Keratin-associated protein 19-3

2

2

High-throughput

0.606

High

1038999

TTC5
Tetratricopeptide repeat protein 5

2

3

High-throughput

0.606

High

1039023

STRBP
Spermatid perinuclear RNA-binding protein

2

2

High-throughput

0.606

High

1039040

NXF1
Nuclear RNA export factor 1

2

1

High-throughput

0.606

High

1039052

TNPO3
Transportin-3

2

5

High-throughput

0.606

High

1038958

CUL3
Cullin-3

2

8

High-throughput

0.601

High

742280

SYUA
Alpha-synuclein

2

1

Small-scale

0.595

High

1028136

NMDE2
Glutamate receptor ionotropic, NMDA 2B

2

15

Small-scale

0.595

High

890650

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.578

High

483927

CALM1
Calmodulin-1

1

20

High-throughput

0.575

High

484001

CALM2
Calmodulin-2

1

20

High-throughput

0.575

High

484119

CALM3
Calmodulin-3

1

20

High-throughput

0.575

High

1038979

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

High-throughput

0.575

High

1038984

DUS1L
tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like

2

2

High-throughput

0.553

High

1039051

RM11
Large ribosomal subunit protein uL11m

2

3

High-throughput

0.553

High

843655

FXR1
RNA-binding protein FXR1

1

18

High-throughput

0.541

High

874379

NR1H2
Oxysterols receptor LXR-beta

1

6

Small-scale

0.536

High

122002

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

1

High-throughput

0.536

High

174861

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

5

High-throughput

0.536

High

215229

STRN
Striatin

1

8

High-throughput

0.536

High

232671

TBCD4
TBC1 domain family member 4

1

1

High-throughput

0.536

High

261257

FLNB
Filamin-B

1

8

High-throughput

0.536

High

331162

DNAL4
Dynein axonemal light chain 4

1

3

High-throughput

0.536

High

472660

F163B
Protein FAM163B

1

2

High-throughput

0.536

High

614026

TBG1
Tubulin gamma-1 chain

1

7

High-throughput

0.536

High

653911

PDE4A
3',5'-cyclic-AMP phosphodiesterase 4A

1

6

High-throughput

0.536

High

657600

ITPI2
Protein ITPRID2

1

3

High-throughput

0.536

High

683326

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

708633

MCM5
DNA replication licensing factor MCM5

1

4

High-throughput

0.536

High

809299

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

12

High-throughput

0.536

High

813016

CAZA2
F-actin-capping protein subunit alpha-2

1

4

High-throughput

0.536

High

904531

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

909531

1433E
14-3-3 protein epsilon

1

10

High-throughput

0.536

High

927014

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

928284

DYL1
Dynein light chain 1, cytoplasmic

1

3

High-throughput

0.536

High

941653

IGBP1
Immunoglobulin-binding protein 1

1

1

High-throughput

0.536

High

944505

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

5

High-throughput

0.536

High

981988

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

1019299

TRI26
Tripartite motif-containing protein 26

1

4

High-throughput

0.536

High

1022816

STRN3
Striatin-3

1

9

High-throughput

0.536

High

1038961

SRC8
Src substrate cortactin

1

6

High-throughput

0.536

High

1038963

ITPR2
Inositol 1,4,5-trisphosphate receptor type 2

1

11

High-throughput

0.536

High

1038965

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

1

11

High-throughput

0.536

High

1038972

DREB
Drebrin

1

6

High-throughput

0.536

High

1038996

CARM1
Histone-arginine methyltransferase CARM1

1

1

High-throughput

0.536

High

1038997

DZIP1
Cilium assembly protein DZIP1

1

4

High-throughput

0.536

High

1039002

SYNPO
Synaptopodin

1

2

High-throughput

0.536

High

1039007

THOC2
THO complex subunit 2

1

2

High-throughput

0.536

High

1039012

ARRD3
Arrestin domain-containing protein 3

1

2

High-throughput

0.536

High

1039014

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.536

High

1039022

TCPQM
T-complex protein 1 subunit theta-like 2

1

3

High-throughput

0.536

High

1039030

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

1039036

STRN4
Striatin-4

1

7

High-throughput

0.536

High

1039043

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

1

4

High-throughput

0.536

High

1039047

BAIP2
BAR/IMD domain-containing adapter protein 2

1

3

High-throughput

0.536

High

1039050

PHOCN
MOB-like protein phocein

1

1

High-throughput

0.536

High

301389

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

2

High-throughput

0.515

High

1038976

KRA63
Keratin-associated protein 6-3

1

2

High-throughput

0.515

High

1038990

Q7KZS0
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.515

High

239979

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

12

High-throughput

0.514

High

245686

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.513

High

1038981

SNPC4
snRNA-activating protein complex subunit 4

1

0

High-throughput

0.513

High

1038982

STRP1
Striatin-interacting protein 1

1

0

High-throughput

0.513

High

1038995

T200A
Transmembrane protein 200A

1

0

High-throughput

0.513

High

1039001

PELI3
E3 ubiquitin-protein ligase pellino homolog 3

1

0

High-throughput

0.513

High

1039003

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.513

High

1039006

NEUA
N-acylneuraminate cytidylyltransferase

1

0

High-throughput

0.513

High

1039010

XPF
DNA repair endonuclease XPF

1

0

High-throughput

0.513

High

1039038

FGOP2
FGFR1 oncogene partner 2

1

0

High-throughput

0.513

High

1039045

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

0

High-throughput

0.513

High

456321

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

1

1

Small-scale

0.501

High

984259

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

15

Small-scale

0.501

High

1035422

SMAD4
Mothers against decapentaplegic homolog 4

1

4

Small-scale

0.501

High

1038970

SMAD2
Mothers against decapentaplegic homolog 2

1

3

Small-scale

0.501

High

1039018

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

2

Small-scale

0.501

High

796073

MAGA9
Melanoma-associated antigen 9

1

6

High-throughput

0.489

High

1038968

PON2
Serum paraoxonase/arylesterase 2

1

1

High-throughput

0.489

High

1038973

INF2
Inverted formin-2

1

1

High-throughput

0.489

High

1038978

KLH26
Kelch-like protein 26

1

2

High-throughput

0.489

High

1038987

SHSA6
Protein shisa-6

1

2

High-throughput

0.489

High

1039000

PUSL1
tRNA pseudouridine synthase-like 1

1

2

High-throughput

0.489

High

1039016

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

1039024

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

1039025

NPAS1
Neuronal PAS domain-containing protein 1

1

1

High-throughput

0.489

High

1039039

MAP10
Microtubule-associated protein 10

1

3

High-throughput

0.489

High

1039044

PNMA2
Paraneoplastic antigen Ma2

1

3

High-throughput

0.489

High

930199

UBC9
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.481

High

562923

STMN1
Stathmin

1

0

Small-scale

0.480

High

128551

DNM1L
Dynamin-1-like protein

1

2

High-throughput

0.479

High

214571

MYO1B
Unconventional myosin-Ib

1

3

High-throughput

0.479

High

243139

SH21A
SH2 domain-containing protein 1A

1

14

High-throughput

0.479

High

301804

TRI37
E3 ubiquitin-protein ligase TRIM37

1

15

High-throughput

0.479

High

322582

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

346719

MYC
Myc proto-oncogene protein

1

8

High-throughput

0.479

High

430169

PROF1
Profilin-1

1

1

Small-scale

0.479

High

552663

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

598473

NF1
Neurofibromin

1

12

High-throughput

0.479

High

651139

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

720399

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

813439

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.479

High

915183

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

8

High-throughput

0.479

High

930836

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

8

High-throughput

0.479

High

940869

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.479

High

969678

KIF23
Kinesin-like protein KIF23

1

5

High-throughput

0.479

High

1038352

HDAC1
Histone deacetylase 1

1

2

High-throughput

0.479

High

1038959

CUL4A
Cullin-4A

1

8

High-throughput

0.479

High

1038969

MARE1
Microtubule-associated protein RP/EB family member 1

1

3

Small-scale

0.479

High

1038974

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

1038980

DACT2
Dapper homolog 2

1

3

High-throughput

0.479

High

1038989

CBAR2
CBY1-interacting BAR domain-containing protein 2

1

2

High-throughput

0.479

High

1038998

ASXL1
Polycomb group protein ASXL1

1

1

High-throughput

0.479

High

1039008

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1039009

TF2H4
General transcription factor IIH subunit 4

1

2

High-throughput

0.479

High

1039011

KPBB
Phosphorylase b kinase regulatory subunit beta

1

2

High-throughput

0.479

High

1039013

PF21A
PHD finger protein 21A

1

1

High-throughput

0.479

High

1039031

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.479

High

1039041

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

1

4

Small-scale

0.479

High

1039042

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

175434

SIVA
Apoptosis regulatory protein Siva

1

0

Small-scale

0.458

High

232153

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

330254

BCL10
B-cell lymphoma/leukemia 10

1

0

Small-scale

0.458

High

1038962

BECN1
Beclin-1

1

0

Small-scale

0.458

High

1039005

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

517240

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.457

High

378041

PRIO
Major prion protein

1

3

High-throughput

0.445

High

708896

MCM7
DNA replication licensing factor MCM7

1

4

Small-scale

0.445

High

1032390

CTBP1
C-terminal-binding protein 1

1

2

High-throughput

0.445

High

1038960

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

6

High-throughput

0.445

High

1038993

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

8

High-throughput

0.445

High

1039019

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

12

High-throughput

0.445

High

1039020

NUDC1
NudC domain-containing protein 1

1

1

High-throughput

0.445

High

1039028

IFIH1
Interferon-induced helicase C domain-containing protein 1

1

2

Small-scale

0.445

High

100736

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

671443

ECHM
Enoyl-CoA hydratase, mitochondrial

1

3

High-throughput

0.437

High

1038994

ZCH18
Zinc finger CCCH domain-containing protein 18

1

2

High-throughput

0.437

High

1039037

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

2

High-throughput

0.437

High

382412

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

0

High-throughput

0.426

High

1038986

PKHG7
Pleckstrin homology domain-containing family G member 7

1

10

High-throughput

0.407

High

1039004

GG6L2
Golgin subfamily A member 6-like protein 2

1

4

High-throughput

0.407

High

831300

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

1039017

ZN488
Zinc finger protein 488

1

0

High-throughput

0.279

Low

1039026

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024