Protein: ADNP
Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein)

Gene: ADNP
Organism: Homo sapiens
Interactions: 176
UniProt ID: Q9H2P0

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001933 - negative regulation of protein phosphorylation
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1027253

CBX3
Chromobox protein homolog 3

9

10

Small-scale

0.755

High

1059867

CHD4
Chromodomain-helicase-DNA-binding protein 4

7

5

Small-scale

0.739

High

949882

CBX1
Chromobox protein homolog 1

5

10

Small-scale

0.723

High

800523

CBX5
Chromobox protein homolog 5

4

10

Small-scale

0.697

High

347872

MYC
Myc proto-oncogene protein

4

3

High-throughput

0.686

High

935228

H31
Histone H3.1

4

4

High-throughput

0.676

High

928463

DYL1
Dynein light chain 1, cytoplasmic

3

1

High-throughput

0.675

High

1260189

HDAC7
Histone deacetylase 7

3

1

High-throughput

0.667

High

1286407

ZN524
Zinc finger protein 524

3

3

High-throughput

0.667

High

1329613

DAXX
Death domain-associated protein 6

3

0

High-throughput

0.646

High

563843

ZSC20
Zinc finger and SCAN domain-containing protein 20

3

0

High-throughput

0.638

High

853706

IMA5
Importin subunit alpha-5

2

3

High-throughput

0.628

High

1038705

HDAC1
Histone deacetylase 1

2

1

High-throughput

0.628

High

1329610

ZN581
Zinc finger protein 581

2

4

High-throughput

0.628

High

1218721

MGAP
MAX gene-associated protein

1

1

High-throughput

0.618

High

1304820

TBX5
T-box transcription factor TBX5

1

1

High-throughput

0.618

High

470156

H2AZ
Histone H2A.Z

2

1

High-throughput

0.611

High

1329603

ZN644
Zinc finger protein 644

2

1

High-throughput

0.611

High

1329612

ZMYM2
Zinc finger MYM-type protein 2

2

2

High-throughput

0.611

High

1152385

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.602

High

244928

BRD4
Bromodomain-containing protein 4

2

2

High-throughput

0.584

High

387492

P53
Cellular tumor antigen p53

2

0

High-throughput

0.559

High

1222572

SLX4
Structure-specific endonuclease subunit SLX4

2

0

High-throughput

0.559

High

126477

FOXE1
Forkhead box protein E1

1

5

High-throughput

0.536

High

168669

IMA6
Importin subunit alpha-6

1

3

High-throughput

0.536

High

208942

FOXS1
Forkhead box protein S1

1

4

High-throughput

0.536

High

318019

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

1

High-throughput

0.536

High

871778

HSP72
Heat shock-related 70 kDa protein 2

1

1

High-throughput

0.536

High

877634

FOXG1
Forkhead box protein G1

1

4

High-throughput

0.536

High

964253

FOXK2
Forkhead box protein K2

1

3

High-throughput

0.536

High

996891

SSRP1
FACT complex subunit SSRP1

1

2

High-throughput

0.536

High

1029317

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

1

High-throughput

0.536

High

1087398

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.536

High

1288029

HDA11
Histone deacetylase 11

1

2

High-throughput

0.536

High

1291292

DYL2
Dynein light chain 2, cytoplasmic

1

1

High-throughput

0.536

High

1318638

FOXQ1
Forkhead box protein Q1

1

5

High-throughput

0.536

High

1329609

FOXJ2
Forkhead box protein J2

1

4

High-throughput

0.536

High

71234

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.513

High

324029

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

358891

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.513

High

508714

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

519085

PIP
Prolactin-inducible protein

1

0

High-throughput

0.513

High

862309

NUBP1
Cytosolic Fe-S cluster assembly factor NUBP1

1

0

High-throughput

0.513

High

1033548

ILK
Integrin-linked protein kinase

1

0

High-throughput

0.513

High

1044701

FHL3
Four and a half LIM domains protein 3

1

0

High-throughput

0.513

High

1061242

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.513

High

1075252

TEAD2
Transcriptional enhancer factor TEF-4

1

0

High-throughput

0.513

High

1078426

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

0

High-throughput

0.513

High

1238351

SYT2
Synaptotagmin-2

1

0

High-throughput

0.513

High

1139745

ZMYM4
Zinc finger MYM-type protein 4

1

2

High-throughput

0.489

High

1329617

PNMA2
Paraneoplastic antigen Ma2

1

1

High-throughput

0.489

High

146276

ARI1A
AT-rich interactive domain-containing protein 1A

1

1

Small-scale

0.479

High

229816

ZN292
Zinc finger protein 292

1

1

High-throughput

0.479

High

232502

KDM1A
Lysine-specific histone demethylase 1A

1

2

High-throughput

0.479

High

261005

H2AY
Core histone macro-H2A.1

1

2

High-throughput

0.479

High

268282

EED
Polycomb protein EED

1

3

High-throughput

0.479

High

316990

KLF8
Krueppel-like factor 8

1

2

High-throughput

0.479

High

331883

NSD2
Histone-lysine N-methyltransferase NSD2

1

1

Small-scale

0.479

High

370420

ESR1
Estrogen receptor

1

3

High-throughput

0.479

High

379854

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

420881

H2B1J
Histone H2B type 1-J

1

2

High-throughput

0.479

High

487757

ANDR
Androgen receptor

1

3

High-throughput

0.479

High

504747

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

553686

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

555643

H2AX
Histone H2AX

1

2

High-throughput

0.479

High

570062

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

586978

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.479

High

632899

TYY1
Transcriptional repressor protein YY1

1

2

High-throughput

0.479

High

717341

CTNB1
Catenin beta-1

1

4

Small-scale

0.479

High

718190

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.479

High

782654

HNF4A
Hepatocyte nuclear factor 4-alpha

1

2

High-throughput

0.479

High

802497

ATRX
Transcriptional regulator ATRX

1

8

Small-scale

0.479

High

808922

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

818459

SOX2
Transcription factor SOX-2

1

4

Small-scale

0.479

High

824376

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

831683

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.479

High

847078

SMCA4
Transcription activator BRG1

1

7

Small-scale

0.479

High

903513

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.479

High

918680

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

934470

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.479

High

952621

H33
Histone H3.3

1

4

High-throughput

0.479

High

974679

MECOM
Histone-lysine N-methyltransferase MECOM

1

1

High-throughput

0.479

High

1018695

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

6

High-throughput

0.479

High

1021161

FOXC1
Forkhead box protein C1

1

4

High-throughput

0.479

High

1024518

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.479

High

1024593

CAF1B
Chromatin assembly factor 1 subunit B

1

2

High-throughput

0.479

High

1026537

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

1035280

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

1

High-throughput

0.479

High

1067135

BRD3
Bromodomain-containing protein 3

1

2

High-throughput

0.479

High

1136919

AHDC1
Transcription factor Gibbin

1

1

High-throughput

0.479

High

1153503

ADNP2
Activity-dependent neuroprotector homeobox protein 2

1

4

High-throughput

0.479

High

1158398

PMF1
Polyamine-modulated factor 1

1

1

High-throughput

0.479

High

1171677

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1189295

POGZ
Pogo transposable element with ZNF domain

1

1

High-throughput

0.479

High

1190718

HDGR2
Hepatoma-derived growth factor-related protein 2

1

2

High-throughput

0.479

High

1236496

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

1238658

SCAI
Protein SCAI

1

1

High-throughput

0.479

High

1243554

CSK23
Casein kinase II subunit alpha 3

1

2

High-throughput

0.479

High

1251625

SMRC2
SWI/SNF complex subunit SMARCC2

1

3

Small-scale

0.479

High

1269594

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1294757

NSL1
Kinetochore-associated protein NSL1 homolog

1

1

High-throughput

0.479

High

1295400

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

1

High-throughput

0.479

High

1300936

CIC
Protein capicua homolog

1

1

High-throughput

0.479

High

1304098

RING2
E3 ubiquitin-protein ligase RING2

1

4

High-throughput

0.479

High

1316698

PCGF6
Polycomb group RING finger protein 6

1

2

High-throughput

0.479

High

1326736

WWTR1
WW domain-containing transcription regulator protein 1

1

1

High-throughput

0.479

High

1327283

MIS12
Protein MIS12 homolog

1

1

High-throughput

0.479

High

1329601

DSN1
Kinetochore-associated protein DSN1 homolog

1

1

High-throughput

0.479

High

1329607

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

672892

CDC27
Cell division cycle protein 27 homolog

1

0

High-throughput

0.460

High

149279

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

295247

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

323125

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

385507

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

523998

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

537063

TRI27
Zinc finger protein RFP

1

0

Small-scale

0.458

High

652223

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

875308

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

917912

H4
Histone H4

1

0

High-throughput

0.458

High

931856

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

932374

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

986988

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.458

High

1042519

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1066680

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1188853

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1198278

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

0

Small-scale

0.458

High

1200656

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1221729

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1282149

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

0

High-throughput

0.458

High

1314921

PHF7
PHD finger protein 7

1

0

High-throughput

0.458

High

1315854

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

1329602

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1329604

LN28A
Protein lin-28 homolog A

1

0

Small-scale

0.458

High

1329608

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1329614

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

402464

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

1329605

PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

1

1

High-throughput

0.445

High

581054

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

1

High-throughput

0.437

High

1133121

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

1

High-throughput

0.437

High

1328245

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.437

High

353729

IGHG1
Immunoglobulin heavy constant gamma 1

1

0

High-throughput

0.426

High

668973

PML
Protein PML

1

0

High-throughput

0.426

High

739282

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.426

High

969537

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

0

High-throughput

0.426

High

1039842

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

1040413

TRA2A
Transformer-2 protein homolog alpha

1

0

High-throughput

0.426

High

1303741

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.426

High

134963

IMA3
Importin subunit alpha-3

1

3

High-throughput

0.408

High

1086316

H31T
Histone H3.1t

1

4

High-throughput

0.408

High

1329611

RRBP1
Ribosome-binding protein 1

1

1

High-throughput

0.407

High

1070094

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

3

0

High-throughput

0.347

High

1329615

DPOG2
DNA polymerase subunit gamma-2

2

0

High-throughput

0.328

High

157078

AIM2
Interferon-inducible protein AIM2

1

0

High-throughput

0.279

Low

176857

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

0

High-throughput

0.279

Low

296827

NOL4
Nucleolar protein 4

1

0

High-throughput

0.279

Low

794423

GRK6
G protein-coupled receptor kinase 6

1

0

High-throughput

0.279

Low

1238116

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

0

High-throughput

0.279

Low

1270228

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.279

Low

1302166

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.279

Low

1329618

PCDBF
Protocadherin beta-15

1

0

High-throughput

0.279

Low

922375

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.269

Low

1326141

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.265

Low

309810

MRP6
ATP-binding cassette sub-family C member 6

1

0

Small-scale

0.249

Low

721418

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1203673

AROS
Active regulator of SIRT1

1

0

High-throughput

0.249

Low

1238798

CC71L
Coiled-coil domain-containing protein 71L

1

0

High-throughput

0.249

Low

1243135

FXL13
F-box and leucine-rich repeat protein 13

1

0

Small-scale

0.249

Low

1314381

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.249

Low

1329600

TXNIP
Thioredoxin-interacting protein

1

0

Small-scale

0.249

Low

1329606

ANLN
Anillin

1

0

High-throughput

0.249

Low

1329616

TF3C4
General transcription factor 3C polypeptide 4

1

0

High-throughput

0.249

Low

725872

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.232

Low

867126

SC24C
Protein transport protein Sec24C

1

0

High-throughput

0.232

Low

1065425

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.232

Low

1075083

MARE2
Microtubule-associated protein RP/EB family member 2

1

0

High-throughput

0.232

Low

1169902

PKHG7
Pleckstrin homology domain-containing family G member 7

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024