Protein: HSDD3
3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3 (At3BETAHSD/D3) (EC 1.1.1.170) (4alpha-carboxysterol-C3-dehydrogenase/C4-decarboxylase isoform 1-3) (Reticulon-like protein B20) (AtRTNLB20) (Sterol-4-alpha-carboxylate 3-dehydrogenase 3, decarboxylating)

Gene: HSDD3, 3BETAHSD/D3
Organism: Arabidopsis thaliana
Interactions: 74
UniProt ID: A9X4U2

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0009506 - plasmodesma
GO:0016126 - sterol biosynthetic process
GO:0102175 - 3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

72527

PIP27
Aquaporin PIP2-7

1

5

High-throughput

0.541

High

72546

VA723
Vesicle-associated membrane protein 723

1

2

High-throughput

0.541

High

72551

AB13G
ABC transporter G family member 13

1

2

High-throughput

0.541

High

72552

AB12G
ABC transporter G family member 12

1

2

High-throughput

0.541

High

72554

CRK2
Cysteine-rich receptor-like protein kinase 2

1

1

High-throughput

0.541

High

72539

Q8GUN1
AT4G31340 protein

1

0

High-throughput

0.518

High

72575

LMBD1
LIMR family protein At3g08930

1

0

High-throughput

0.518

High

72512

Y2289
Probable LRR receptor-like serine/threonine-protein kinase At2g28960

1

2

High-throughput

0.494

High

72514

GSO1
LRR receptor-like serine/threonine-protein kinase GSO1

1

1

High-throughput

0.494

High

72515

GHR1
LRR receptor-like serine/threonine-protein kinase GHR1

1

2

High-throughput

0.494

High

72516

HSL2
LRR receptor-like serine/threonine-protein kinase HSL2

1

1

High-throughput

0.494

High

72518

F4IS71
RING/FYVE/PHD zinc finger superfamily protein

1

3

High-throughput

0.494

High

72523

C76C1
Cytochrome P450 76C1

1

2

High-throughput

0.494

High

72528

PIP13
Aquaporin PIP1-3

1

5

High-throughput

0.494

High

72530

CDS3
Phosphatidate cytidylyltransferase 3

1

1

High-throughput

0.494

High

72532

OLEO2
Oleosin 21.2 kDa

1

2

High-throughput

0.494

High

72537

Q6DR41
Transmembrane protein

1

1

High-throughput

0.494

High

72540

CRK14
Cysteine-rich receptor-like protein kinase 14

1

1

High-throughput

0.494

High

72542

ALE2
Receptor-like serine/threonine-protein kinase ALE2

1

1

High-throughput

0.494

High

72543

TMN10
Transmembrane 9 superfamily member 10

1

3

High-throughput

0.494

High

72547

Q8VZC2
At1g78490

1

3

High-throughput

0.494

High

72549

RPKL
Receptor protein kinase-like protein At4g34220

1

2

High-throughput

0.494

High

72550

LRK55
L-type lectin-domain containing receptor kinase V.5

1

2

High-throughput

0.494

High

72553

SRF6
Protein STRUBBELIG-RECEPTOR FAMILY 6

1

1

High-throughput

0.494

High

72557

DTX55
Protein DETOXIFICATION 55

1

2

High-throughput

0.494

High

72561

NAP5
Probable non-intrinsic ABC protein 5

1

1

High-throughput

0.494

High

72563

AB20G
ABC transporter G family member 20

1

2

High-throughput

0.494

High

72564

NIPA3
Probable magnesium transporter NIPA3

1

1

High-throughput

0.494

High

72566

CRR38
Cysteine-rich repeat secretory protein 38

1

2

High-throughput

0.494

High

72567

DTX19
Protein DETOXIFICATION 19

1

2

High-throughput

0.494

High

72570

RLP30
Receptor-like protein 30

1

1

High-throughput

0.494

High

72571

RPK2
LRR receptor-like serine/threonine-protein kinase RPK2

1

2

High-throughput

0.494

High

72577

LHTL8
Lysine histidine transporter-like 8

1

2

High-throughput

0.494

High

72580

LRK57
L-type lectin-domain containing receptor kinase V.7

1

3

High-throughput

0.494

High

72582

DTX53
Protein DETOXIFICATION 53

1

2

High-throughput

0.494

High

72583

Q9ZW05
Transmembrane protein

1

1

High-throughput

0.494

High

72513

C0LGM1
Leucine-rich repeat protein kinase family protein

1

2

High-throughput

0.481

High

72526

M910
Uncharacterized mitochondrial protein AtMg00910

1

1

High-throughput

0.439

High

72529

Q0WSW1
RING/U-box superfamily protein

1

4

High-throughput

0.439

High

72533

Q3E7H2
Ankyrin repeat family protein

1

2

High-throughput

0.439

High

72536

Q494N8
Oleosin

1

2

High-throughput

0.439

High

72538

Q6NKQ5
At2g01275

1

3

High-throughput

0.439

High

72544

Q8VY23
C3H4 type zinc finger protein

1

4

High-throughput

0.439

High

72568

Q9LYI6
Alkaline phytoceramidase

1

1

High-throughput

0.439

High

45935

A0A1P8AZ30
RING/FYVE/PHD zinc finger superfamily protein

1

4

High-throughput

0.417

High

72521

F4JZD5
Alkaline phytoceramidase

1

1

High-throughput

0.417

High

72524

O65539
Uncharacterized protein AT4g32600

1

4

High-throughput

0.417

High

72525

O82308
Oleosin

1

2

High-throughput

0.417

High

72531

Q27GL4
Cytochrome B/B6 protein

1

1

High-throughput

0.417

High

72562

Q9LF32
Ankyrin repeat family protein

1

2

High-throughput

0.417

High

72576

Q9SUA5
Uncharacterized protein AT4g26580

1

5

High-throughput

0.417

High

72579

Q9ZQC2
Putative receptor-like protein kinase

1

2

High-throughput

0.417

High

51552

CLT2
Protein CLT2, chloroplastic

1

0

High-throughput

0.282

High

72517

F4IBA7
Transmembrane protein

1

0

High-throughput

0.282

High

72519

F4IZC0
Transmembrane protein, putative

1

0

High-throughput

0.282

High

72520

F4JMN0
YCF49-like protein

1

0

High-throughput

0.282

High

72522

CESA2
Cellulose synthase A catalytic subunit 2 [UDP-forming]

1

0

High-throughput

0.282

High

72534

DMP10
Protein DMP10

1

0

High-throughput

0.282

High

72535

CLE3
CLAVATA3/ESR

1

0

High-throughput

0.282

High

72541

KCO1
Two-pore potassium channel 1

1

0

High-throughput

0.282

High

72545

Q8VY59
At3g27200

1

0

High-throughput

0.282

High

72548

Q945Q2
AT3g59090/F17J16_140

1

0

High-throughput

0.282

High

72555

OPT1
Oligopeptide transporter 1

1

0

High-throughput

0.282

High

72556

PNSB5
Photosynthetic NDH subunit of subcomplex B 5, chloroplastic

1

0

High-throughput

0.282

High

72558

WAXS6
Probable long-chain-alcohol O-fatty-acyltransferase 6

1

0

High-throughput

0.282

High

72559

NRT23
High affinity nitrate transporter 2.3

1

0

High-throughput

0.282

High

72560

VA0E1
V-type proton ATPase subunit e1

1

0

High-throughput

0.282

High

72565

TET11
Tetraspanin-11

1

0

High-throughput

0.282

High

72569

CX5C2
Cytochrome c oxidase subunit 5C-2

1

0

High-throughput

0.282

High

72572

Q9SA06
F28K20.6 protein

1

0

High-throughput

0.282

High

72573

Q9SD79
Wiskott-aldrich syndrome family protein, putative

1

0

High-throughput

0.282

High

72574

Q9SLC0
Expressed protein

1

0

High-throughput

0.282

High

72578

Q9SY38
Pyrroline-5-carboxylate reductase

1

0

High-throughput

0.282

High

72581

ALS3
Protein ALUMINUM SENSITIVE 3

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025