Protein: HSP74
Heat shock 70 kDa protein 4 (Ischemia responsive 94 kDa protein)

Gene: HSP74, Hspa4
Organism: Rattus norvegicus
Interactions: 19
UniProt ID: O88600

Gene Ontology (top 5):
GO:0000774 - adenyl-nucleotide exchange factor activity
GO:0001822 - kidney development
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

312683

PEX5
Peroxisomal targeting signal 1 receptor

1

8

Small-scale

0.647

High

72711

BAG1
BAG family molecular chaperone regulator 1

1

6

Small-scale

0.618

High

312685

ITM2B
Integral membrane protein 2B

1

3

High-throughput

0.536

High

312676

GCR
Glucocorticoid receptor

1

20

Small-scale

0.501

High

312679

CP27A
Sterol 26-hydroxylase, mitochondrial

1

4

Small-scale

0.501

High

98642

F1LST4
Microtubule-associated protein

1

20

High-throughput

0.479

High

237288

SOX10
Transcription factor SOX-10

1

7

Small-scale

0.479

High

312677

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.479

High

312678

P53
Cellular tumor antigen p53

1

10

Small-scale

0.479

High

312682

SYUA
Alpha-synuclein

1

7

High-throughput

0.479

High

312684

RD23B
UV excision repair protein RAD23 homolog B

1

16

Small-scale

0.479

High

312686

SUMO3
Small ubiquitin-related modifier 3

1

8

High-throughput

0.479

High

312688

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]

1

9

High-throughput

0.479

High

73558

B2GV28
Cytochrome P450

1

7

Small-scale

0.457

High

312674

CP1A1
Cytochrome P450 1A1

1

7

Small-scale

0.457

High

312675

CP2E1
Cytochrome P450 2E1

1

7

Small-scale

0.457

High

312680

TAU
Microtubule-associated protein tau

1

19

High-throughput

0.445

High

312681

MK03
Mitogen-activated protein kinase 3

1

9

High-throughput

0.445

High

312687

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

7

Small-scale

0.437

High


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Last updated: 11Aug2025