Protein: AKT1
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (RAC-PK-alpha)

Gene: AKT1
Organism: Rattus norvegicus
Interactions: 21
UniProt ID: P47196

Gene Ontology (top 5):
GO:0001649 - osteoblast differentiation
GO:0001893 - maternal placenta development
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0002042 - cell migration involved in sprouting angiogenesis
GO:0002931 - response to ischemia

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

613668

GSK3B
Glycogen synthase kinase-3 beta

3

20

Small-scale

0.845

High

689799

ARBK1
Beta-adrenergic receptor kinase 1

1

16

Small-scale

0.724

High

866340

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

19

Small-scale

0.690

High

613665

GSK3A
Glycogen synthase kinase-3 alpha

1

20

Small-scale

0.647

High

866344

SH2B2
SH2B adapter protein 2

1

14

Small-scale

0.647

High

93209

D4A254
PH domain leucine-rich repeat-containing protein phosphatase 2

1

16

Small-scale

0.618

High

866337

HS90A
Heat shock protein HSP 90-alpha

1

20

Small-scale

0.618

High

866341

PKN1
Serine/threonine-protein kinase N1

1

16

Small-scale

0.618

High

866342

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.618

High

72714

BAG1
BAG family molecular chaperone regulator 1

1

0

Small-scale

0.586

High

148457

PKN2
Serine/threonine-protein kinase N2

1

17

Small-scale

0.575

High

92850

D3ZBQ1
Forkhead box O3

1

11

Small-scale

0.561

High

866338

SMAD3
Mothers against decapentaplegic homolog 3

1

9

Small-scale

0.534

High

266999

SMAD2
Mothers against decapentaplegic homolog 2

1

9

Small-scale

0.515

High

415975

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

6

Small-scale

0.515

High

866339

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

Small-scale

0.504

High

267002

SMAD4
Mothers against decapentaplegic homolog 4

1

9

Small-scale

0.479

High

312210

SMAD7
Mothers against decapentaplegic homolog 7

1

9

Small-scale

0.479

High

866343

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

1

9

Small-scale

0.479

High

561400

FCERB
High affinity immunoglobulin epsilon receptor subunit beta

1

0

Small-scale

0.458

High

604495

TISB
mRNA decay activator protein ZFP36L1

1

2

Small-scale

0.338

High


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Last updated: 11Aug2025