Interactor 1: AKT1 (P47196)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (RAC-PK-alpha)
Gene: AKT1
Interactor 2: SH2B2 (Q9Z200)
SH2B adapter protein 2 (Adapter protein with pleckstrin homology and Src homology 2 domains) (SH2 and PH domain-containing adapter protein APS)
Gene: SH2B2
Species: Rattus norvegicus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16141217 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~PH, PH~Pkinase |
| Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0008286 - insulin receptor signaling pathway GO:0035556 - intracellular signal transduction |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025