Protein: ARI1
E3 ubiquitin-protein ligase ARIH1 (EC 2.3.2.31) (H7-AP2) (HHARI) (Monocyte protein 6) (MOP-6) (Protein ariadne-1 homolog) (ARI-1) (UbcH7-binding protein) (UbcM4-interacting protein) (Ubiquitin-conjugating enzyme E2-binding protein 1)

Gene: ARI1, ARIH1
Organism: Homo sapiens
Interactions: 219
UniProt ID: Q9Y4X5

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

932603

UB2L3
Ubiquitin-conjugating enzyme E2 L3

19

20

Small-scale

0.991

High

1377910

ARI1
E3 ubiquitin-protein ligase ARIH1

12

17

Small-scale

0.978

High

1041302

CUL1
Cullin-1

5

14

Small-scale

0.939

High

1042929

CUL3
Cullin-3

4

14

Small-scale

0.895

High

1079643

NEDD8
NEDD8

4

10

Small-scale

0.893

High

849498

UB2D1
Ubiquitin-conjugating enzyme E2 D1

4

20

Small-scale

0.888

High

476630

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

20

Small-scale

0.862

High

921490

RBX1
E3 ubiquitin-protein ligase RBX1

3

6

Small-scale

0.853

High

229170

PRKN
E3 ubiquitin-protein ligase parkin

3

16

Small-scale

0.827

High

1303065

UHRF1
E3 ubiquitin-protein ligase UHRF1

2

4

High-throughput

0.811

High

1041515

CUL2
Cullin-2

2

14

Small-scale

0.789

High

895968

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

Small-scale

0.778

High

896576

UBE2N
Ubiquitin-conjugating enzyme E2 N

2

20

Small-scale

0.768

High

1072493

ELOB
Elongin-B

2

2

High-throughput

0.754

High

1356385

FBW1B
F-box/WD repeat-containing protein 11

6

12

High-throughput

0.732

High

1377165

FBW1A
F-box/WD repeat-containing protein 1A

4

11

High-throughput

0.697

High

1330598

FXL15
F-box/LRR-repeat protein 15

4

3

High-throughput

0.694

High

1043330

CUL4A
Cullin-4A

1

14

Small-scale

0.691

High

1318692

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

16

High-throughput

0.691

High

402673

JUN
Transcription factor Jun

4

11

High-throughput

0.691

High

624622

CCNE1
G1/S-specific cyclin-E1

4

3

Small-scale

0.683

High

214429

SPOP
Speckle-type POZ protein

3

11

Small-scale

0.670

High

262636

TULP3
Tubby-related protein 3

3

1

High-throughput

0.667

High

568284

ATF7
Cyclic AMP-dependent transcription factor ATF-7

3

10

High-throughput

0.667

High

1045952

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

3

6

High-throughput

0.667

High

1183915

KCTD9
BTB/POZ domain-containing protein KCTD9

3

7

High-throughput

0.667

High

1201319

KBTB6
Kelch repeat and BTB domain-containing protein 6

3

14

High-throughput

0.667

High

1221256

KLHL7
Kelch-like protein 7

3

12

High-throughput

0.667

High

1232301

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

3

4

High-throughput

0.667

High

1237990

ZFP41
Zinc finger protein 41 homolog

3

12

High-throughput

0.667

High

1262100

KBTB7
Kelch repeat and BTB domain-containing protein 7

3

13

High-throughput

0.667

High

1264770

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

3

7

High-throughput

0.667

High

1287637

ZN501
Zinc finger protein 501

3

9

High-throughput

0.667

High

1306336

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

3

5

High-throughput

0.667

High

1309208

KLDC3
Kelch domain-containing protein 3

3

11

High-throughput

0.667

High

1327889

PUS7L
Pseudouridylate synthase PUS7L

3

1

High-throughput

0.667

High

1328946

EPN3
Epsin-3

3

8

High-throughput

0.667

High

1330042

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

3

6

High-throughput

0.667

High

1333837

ECT2
Protein ECT2

3

10

High-throughput

0.667

High

1377425

KLDC2
Kelch domain-containing protein 2

3

13

High-throughput

0.667

High

1297383

UB2E2
Ubiquitin-conjugating enzyme E2 E2

1

20

Small-scale

0.647

High

1344025

BIRC6
Baculoviral IAP repeat-containing protein 6

1

20

Small-scale

0.647

High

237357

IF4E2
Eukaryotic translation initiation factor 4E type 2

2

3

Small-scale

0.636

High

161899

ZN263
Zinc finger protein 263

2

13

High-throughput

0.628

High

265448

KTNA1
Katanin p60 ATPase-containing subunit A1

2

12

High-throughput

0.628

High

547863

ATF2
Cyclic AMP-dependent transcription factor ATF-2

2

9

High-throughput

0.628

High

557010

CREB1
Cyclic AMP-responsive element-binding protein 1

2

2

High-throughput

0.628

High

566803

JUNB
Transcription factor JunB

2

11

High-throughput

0.628

High

567906

HXB9
Homeobox protein Hox-B9

2

3

High-throughput

0.628

High

568110

JUND
Transcription factor JunD

2

9

High-throughput

0.628

High

579166

ATF1
Cyclic AMP-dependent transcription factor ATF-1

2

7

High-throughput

0.628

High

599754

TNAP3
Tumor necrosis factor alpha-induced protein 3

2

8

High-throughput

0.628

High

678812

HXA10
Homeobox protein Hox-A10

2

2

High-throughput

0.628

High

679019

HXC9
Homeobox protein Hox-C9

2

7

High-throughput

0.628

High

899937

ISL1
Insulin gene enhancer protein ISL-1

2

3

High-throughput

0.628

High

962727

IRF9
Interferon regulatory factor 9

2

5

High-throughput

0.628

High

973657

CREB5
Cyclic AMP-responsive element-binding protein 5

2

7

High-throughput

0.628

High

1168458

ZN852
Zinc finger protein 852

2

8

High-throughput

0.628

High

1234323

SRBD1
S1 RNA-binding domain-containing protein 1

2

1

High-throughput

0.628

High

1263063

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

3

High-throughput

0.628

High

1264316

BBX
HMG box transcription factor BBX

2

1

High-throughput

0.628

High

1283503

ISL2
Insulin gene enhancer protein ISL-2

2

3

High-throughput

0.628

High

1297974

TEAN2
Transcription elongation factor A N-terminal and central domain-containing protein 2

2

1

High-throughput

0.628

High

1310356

PDD2L
Programmed cell death protein 2-like

2

2

High-throughput

0.628

High

1328109

DDX47
Probable ATP-dependent RNA helicase DDX47

2

15

High-throughput

0.628

High

1344292

BATF3
Basic leucine zipper transcriptional factor ATF-like 3

2

7

High-throughput

0.628

High

1356573

FBXW2
F-box/WD repeat-containing protein 2

2

13

High-throughput

0.628

High

1254610

MAGE2
Melanoma-associated antigen E2

2

5

High-throughput

0.621

High

159108

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

20

Small-scale

0.618

High

1030062

TIF1B
Transcription intermediary factor 1-beta

1

15

High-throughput

0.618

High

1172430

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.618

High

532334

ZNF35
Zinc finger protein 35

2

11

High-throughput

0.612

High

929134

SKP1
S-phase kinase-associated protein 1

2

1

High-throughput

0.611

High

1356340

FBX3
F-box only protein 3

2

1

High-throughput

0.611

High

1252649

SHKB1
SH3KBP1-binding protein 1

3

7

High-throughput

0.609

High

1377912

KCTD3
BTB/POZ domain-containing protein KCTD3

3

7

High-throughput

0.609

High

1216202

TF2LY
Homeobox protein TGIF2LY

2

0

High-throughput

0.602

High

1301597

CRML
Protein cramped-like

2

0

High-throughput

0.602

High

1349508

THYN1
Thymocyte nuclear protein 1

2

0

High-throughput

0.602

High

1356344

FBXL5
F-box/LRR-repeat protein 5

2

0

High-throughput

0.602

High

1306933

HAUS7
HAUS augmin-like complex subunit 7

2

0

High-throughput

0.585

High

804159

CDN1B
Cyclin-dependent kinase inhibitor 1B

2

3

Small-scale

0.585

High

1281514

FBXW7
F-box/WD repeat-containing protein 7

2

10

Small-scale

0.584

High

1354994

ZRAN1
Ubiquitin thioesterase ZRANB1

2

16

High-throughput

0.584

High

1241336

CAMKV
CaM kinase-like vesicle-associated protein

2

3

High-throughput

0.574

High

1317646

RHBT2
Rho-related BTB domain-containing protein 2

2

9

High-throughput

0.574

High

1120832

KLH12
Kelch-like protein 12

2

12

High-throughput

0.571

High

302333

SC31A
Protein transport protein Sec31A

1

11

High-throughput

0.561

High

1344632

FBX6
F-box only protein 6

2

0

High-throughput

0.559

High

1072089

PCBP1
Poly(rC)-binding protein 1

1

11

Small-scale

0.552

High

388825

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.541

High

197433

SERA
D-3-phosphoglycerate dehydrogenase

1

4

High-throughput

0.536

High

242613

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

2

High-throughput

0.536

High

254653

ZN623
Zinc finger protein 623

1

11

High-throughput

0.536

High

313666

ZIC2
Zinc finger protein ZIC 2

1

17

High-throughput

0.536

High

739889

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.536

High

804385

NOTC1
Neurogenic locus notch homolog protein 1

1

5

High-throughput

0.536

High

911777

RUXE
Small nuclear ribonucleoprotein E

1

1

High-throughput

0.536

High

1128451

ZN484
Zinc finger protein 484

1

10

High-throughput

0.536

High

1230906

ZN687
Zinc finger protein 687

1

12

High-throughput

0.536

High

1242710

ZN248
Zinc finger protein 248

1

8

High-throughput

0.536

High

1259484

SETD7
Histone-lysine N-methyltransferase SETD7

1

2

High-throughput

0.536

High

1261315

RN138
E3 ubiquitin-protein ligase RNF138

1

16

High-throughput

0.536

High

1312111

RBM42
RNA-binding protein 42

1

11

High-throughput

0.536

High

1326046

NDEL1
Nuclear distribution protein nudE-like 1

1

8

High-throughput

0.536

High

1377915

KC1G3
Casein kinase I isoform gamma-3

1

13

High-throughput

0.536

High

1230258

ZFP82
Zinc finger protein 82 homolog

1

3

High-throughput

0.515

High

828955

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

985273

HME1
Homeobox protein engrailed-1

1

0

High-throughput

0.513

High

855831

VAV2
Guanine nucleotide exchange factor VAV2

1

7

High-throughput

0.508

High

1292415

DCNL1
DCN1-like protein 1

1

2

Small-scale

0.501

High

664394

CCN2
CCN family member 2

1

1

High-throughput

0.489

High

957294

FBLN2
Fibulin-2

1

10

High-throughput

0.489

High

1201415

LRRT3
Leucine-rich repeat transmembrane neuronal protein 3

1

2

High-throughput

0.489

High

1238373

SYT2
Synaptotagmin-2

1

4

High-throughput

0.489

High

1082170

CRY1
Cryptochrome-1

1

0

High-throughput

0.480

High

154883

TCRG1
Transcription elongation regulator 1

1

6

High-throughput

0.479

High

159293

CSKP
Peripheral plasma membrane protein CASK

1

16

Small-scale

0.479

High

232614

KDM1A
Lysine-specific histone demethylase 1A

1

2

High-throughput

0.479

High

245132

BRD4
Bromodomain-containing protein 4

1

4

High-throughput

0.479

High

256180

OBSL1
Obscurin-like protein 1

1

6

High-throughput

0.479

High

259806

PDCD6
Programmed cell death protein 6

1

10

High-throughput

0.479

High

264759

VP26A
Vacuolar protein sorting-associated protein 26A

1

3

High-throughput

0.479

High

295457

RECQ4
ATP-dependent DNA helicase Q4

1

14

High-throughput

0.479

High

307235

KLHL2
Kelch-like protein 2

1

12

High-throughput

0.479

High

321678

AP2A1
AP-2 complex subunit alpha-1

1

5

High-throughput

0.479

High

321953

RIGI
Antiviral innate immune response receptor RIG-I

1

18

Small-scale

0.479

High

658459

DPOD1
DNA polymerase delta catalytic subunit

1

3

High-throughput

0.479

High

673916

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

1

1

High-throughput

0.479

High

749990

BRCA1
Breast cancer type 1 susceptibility protein

1

9

High-throughput

0.479

High

770710

TXLNA
Alpha-taxilin

1

20

High-throughput

0.479

High

772223

VHL
von Hippel-Lindau disease tumor suppressor

1

1

High-throughput

0.479

High

780387

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

782017

PERI
Peripherin

1

18

High-throughput

0.479

High

809495

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

2

High-throughput

0.479

High

832954

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

6

High-throughput

0.479

High

836120

GSK3B
Glycogen synthase kinase-3 beta

1

6

Small-scale

0.479

High

868825

ATX1
Ataxin-1

1

2

High-throughput

0.479

High

875476

TERA
Transitional endoplasmic reticulum ATPase

1

8

High-throughput

0.479

High

876550

AFAD
Afadin

1

13

High-throughput

0.479

High

878269

SEC13
Protein SEC13 homolog

1

12

High-throughput

0.479

High

914586

ERF1
Eukaryotic peptide chain release factor subunit 1

1

3

High-throughput

0.479

High

918975

RAB1A
Ras-related protein Rab-1A

1

3

High-throughput

0.479

High

952904

FOXK1
Forkhead box protein K1

1

2

High-throughput

0.479

High

992332

DPOE1
DNA polymerase epsilon catalytic subunit A

1

3

High-throughput

0.479

High

1019703

ILF2
Interleukin enhancer-binding factor 2

1

5

High-throughput

0.479

High

1037030

SQSTM
Sequestosome-1

1

2

Small-scale

0.479

High

1047476

PEBB
Core-binding factor subunit beta

1

1

High-throughput

0.479

High

1049932

UBP2L
Ubiquitin-associated protein 2-like

1

10

High-throughput

0.479

High

1050595

SIM2
Single-minded homolog 2

1

5

Small-scale

0.479

High

1072340

ELOC
Elongin-C

1

2

High-throughput

0.479

High

1121221

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

13

High-throughput

0.479

High

1121286

KLH22
Kelch-like protein 22

1

12

High-throughput

0.479

High

1135240

RBM26
RNA-binding protein 26

1

11

High-throughput

0.479

High

1154311

PDE12
2',5'-phosphodiesterase 12

1

1

High-throughput

0.479

High

1161758

KLD10
Kelch domain-containing protein 10

1

13

High-throughput

0.479

High

1173793

ACD11
Acyl-CoA dehydrogenase family member 11

1

8

High-throughput

0.479

High

1193243

ZER1
Protein zer-1 homolog

1

1

High-throughput

0.479

High

1204485

FBX11
F-box only protein 11

1

1

High-throughput

0.479

High

1242542

RCBT1
RCC1 and BTB domain-containing protein 1

1

10

High-throughput

0.479

High

1244019

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1245074

FBH1
F-box DNA helicase 1

1

1

High-throughput

0.479

High

1266160

DDX1
ATP-dependent RNA helicase DDX1

1

11

High-throughput

0.479

High

1266490

PSMF1
Proteasome inhibitor PI31 subunit

1

1

High-throughput

0.479

High

1268480

APBP2
Amyloid protein-binding protein 2

1

9

High-throughput

0.479

High

1272419

RENT1
Regulator of nonsense transcripts 1

1

3

High-throughput

0.479

High

1287449

OPTN
Optineurin

1

18

High-throughput

0.479

High

1288520

FMT
Methionyl-tRNA formyltransferase, mitochondrial

1

1

High-throughput

0.479

High

1295635

FEM1C
Protein fem-1 homolog C

1

3

High-throughput

0.479

High

1297687

KLH15
Kelch-like protein 15

1

13

High-throughput

0.479

High

1300066

BTBD9
BTB/POZ domain-containing protein 9

1

17

High-throughput

0.479

High

1301758

WRIP1
ATPase WRNIP1

1

7

High-throughput

0.479

High

1311125

BTBDA
BTB/POZ domain-containing protein 10

1

2

High-throughput

0.479

High

1314865

CAR10
Caspase recruitment domain-containing protein 10

1

7

High-throughput

0.479

High

1314916

SSBP3
Single-stranded DNA-binding protein 3

1

4

High-throughput

0.479

High

1315088

BTBD2
BTB/POZ domain-containing protein 2

1

15

High-throughput

0.479

High

1318147

REN3B
Regulator of nonsense transcripts 3B

1

3

High-throughput

0.479

High

1319193

ZY11B
Protein zyg-11 homolog B

1

1

High-throughput

0.479

High

1327503

BTBD1
BTB/POZ domain-containing protein 1

1

16

High-throughput

0.479

High

1327771

KLH25
Kelch-like protein 25

1

10

High-throughput

0.479

High

1331082

FA83D
Protein FAM83D

1

3

High-throughput

0.479

High

1334483

ELP3
Elongator complex protein 3

1

1

High-throughput

0.479

High

1334930

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

9

High-throughput

0.479

High

1345539

SYFB
Phenylalanine--tRNA ligase beta subunit

1

2

High-throughput

0.479

High

1348225

TBA8
Tubulin alpha-8 chain

1

13

High-throughput

0.479

High

1350372

KLHL9
Kelch-like protein 9

1

12

High-throughput

0.479

High

1350485

KLH13
Kelch-like protein 13

1

13

High-throughput

0.479

High

1354387

PEF1
Peflin

1

12

Small-scale

0.479

High

1354645

FXL17
F-box/LRR-repeat protein 17

1

2

High-throughput

0.479

High

1355711

DACH1
Dachshund homolog 1

1

1

High-throughput

0.479

High

1355836

HERC5
E3 ISG15--protein ligase HERC5

1

8

Small-scale

0.479

High

1377082

COF2
Cofilin-2

1

6

High-throughput

0.479

High

1377257

NISCH
Nischarin

1

9

High-throughput

0.479

High

1377706

FBX7
F-box only protein 7

1

1

High-throughput

0.479

High

1377778

HBS1L
HBS1-like protein

1

9

High-throughput

0.479

High

1377911

IPP
Actin-binding protein IPP

1

12

High-throughput

0.479

High

1377913

MAFB
Transcription factor MafB

1

5

High-throughput

0.479

High

1377914

SNCAP
Synphilin-1

1

9

Small-scale

0.479

High

72385

B3KW44
tRNA N(3)-methylcytidine methyltransferase

1

0

High-throughput

0.458

High

301113

FBX21
F-box only protein 21

1

0

High-throughput

0.458

High

721879

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

959109

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

1102028

CTC1
CST complex subunit CTC1

1

0

High-throughput

0.458

High

1191996

FBX33
F-box only protein 33

1

0

High-throughput

0.458

High

1281888

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1336230

ZSWM6
Zinc finger SWIM domain-containing protein 6

1

0

High-throughput

0.458

High

975134

CAV1
Caveolin-1

1

1

High-throughput

0.437

High

1121512

KLH26
Kelch-like protein 26

1

13

High-throughput

0.437

High

1223685

MICU2
Calcium uptake protein 2, mitochondrial

1

6

High-throughput

0.437

High

1286625

NSUN4
5-methylcytosine rRNA methyltransferase NSUN4

1

7

High-throughput

0.437

High

1300857

SNX18
Sorting nexin-18

1

10

High-throughput

0.437

High

1308572

NIPS1
Protein NipSnap homolog 1

1

1

High-throughput

0.437

High

1079810

EREP1
Endosomal transmembrane epsin interactor 1

1

2

Small-scale

0.417

High

1129314

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

3

0

High-throughput

0.347

High

1224723

SELH
Selenoprotein H

3

0

High-throughput

0.347

High

1300424

TEFM
Transcription elongation factor, mitochondrial

3

0

High-throughput

0.347

High

873775

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.279

Low

483733

CT456
Cancer/testis antigen family 45 member A6

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024