Protein: DNS2A
Deoxyribonuclease-2-alpha (EC 3.1.22.1) (Acid DNase) (Deoxyribonuclease II alpha) (DNase II alpha) (Lysosomal DNase II) (R31240_2)

Gene: DNS2A, DNASE2
Organism: Homo sapiens
Interactions: 18
UniProt ID: O00115

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0004531 - deoxyribonuclease II activity
GO:0005764 - lysosome
GO:0006259 - DNA metabolic process
GO:0006309 - apoptotic DNA fragmentation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

122426

CALX
Calnexin

3

1

High-throughput

0.650

High

122436

RUVB2
RuvB-like 2

1

1

High-throughput

0.515

High

122437

RUVB1
RuvB-like 1

1

1

High-throughput

0.515

High

122422

TMPS2
Transmembrane protease serine 2

1

1

High-throughput

0.479

High

122427

TERA
Transitional endoplasmic reticulum ATPase

1

1

Small-scale

0.479

High

122431

TM192
Transmembrane protein 192

1

0

High-throughput

0.458

High

122435

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.437

High

122425

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

122428

QOR
Quinone oxidoreductase

1

0

High-throughput

0.426

High

122421

CLGN
Calmegin

1

1

High-throughput

0.407

High

122424

C1QRF
C1q-related factor

1

1

High-throughput

0.407

High

122434

FBX6
F-box only protein 6

2

0

High-throughput

0.298

High

122432

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.251

Low

122423

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

122429

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

0

High-throughput

0.249

Low

122430

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

73743

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

0

High-throughput

0.232

Low

122433

JMJD8
JmjC domain-containing protein 8

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025