Protein: ELL2
RNA polymerase II elongation factor ELL2

Gene: ELL2
Organism: Homo sapiens
Interactions: 54
UniProt ID: O00472

Gene Ontology (top 5):
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0005654 - nucleoplasm
GO:0006368 - transcription elongation by RNA polymerase II
GO:0008023 - transcription elongation factor complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

130172

AFF4
AF4/FMR2 family member 4

7

16

Small-scale

0.966

High

130169

EAF1
ELL-associated factor 1

7

5

Small-scale

0.965

High

130150

AFF1
AF4/FMR2 family member 1

3

17

Small-scale

0.861

High

130168

EAF2
ELL-associated factor 2

2

5

Small-scale

0.789

High

130149

CDK9
Cyclin-dependent kinase 9

5

7

Small-scale

0.709

High

130155

ENL
Protein ENL

4

15

Small-scale

0.699

High

130146

AF9
Protein AF-9

4

12

Small-scale

0.694

High

130147

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

2

High-throughput

0.628

High

48584

MED19
Mediator of RNA polymerase II transcription subunit 19

2

1

High-throughput

0.601

High

130133

MED26
Mediator of RNA polymerase II transcription subunit 26

2

3

High-throughput

0.601

High

130174

ICE1
Little elongation complex subunit 1

2

2

Small-scale

0.601

High

130165

Q8TAX5
AFF4 protein

1

7

High-throughput

0.594

High

130128

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

High-throughput

0.580

High

130162

SIAH1
E3 ubiquitin-protein ligase SIAH1

2

1

Small-scale

0.575

High

130129

CCNT1
Cyclin-T1

1

11

High-throughput

0.536

High

130130

CCNT2
Cyclin-T2

1

11

High-throughput

0.536

High

130160

CTR9
RNA polymerase-associated protein CTR9 homolog

1

3

High-throughput

0.536

High

130131

PR40A
Pre-mRNA-processing factor 40 homolog A

1

13

High-throughput

0.515

High

130153

RAN
GTP-binding nuclear protein Ran

1

10

High-throughput

0.515

High

130173

UBQL1
Ubiquilin-1

1

3

High-throughput

0.515

High

130127

CSKP
Peripheral plasma membrane protein CASK

1

7

High-throughput

0.494

High

130151

ATX1
Ataxin-1

1

0

High-throughput

0.493

High

130152

CASP6
Caspase-6

1

0

High-throughput

0.493

High

130164

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.493

High

130132

OFD1
Centriole and centriolar satellite protein OFD1

1

9

High-throughput

0.489

High

130134

B3A2
Anion exchange protein 2

1

2

High-throughput

0.489

High

130156

EFR3A
Protein EFR3 homolog A

1

2

High-throughput

0.489

High

130161

NBEL2
Neurobeachin-like protein 2

1

4

High-throughput

0.489

High

130142

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

2

High-throughput

0.479

High

130154

KIF23
Kinesin-like protein KIF23

1

5

High-throughput

0.479

High

130158

IRF4
Interferon regulatory factor 4

1

1

Small-scale

0.479

High

130137

LAMP2
Lysosome-associated membrane glycoprotein 2

1

6

High-throughput

0.470

High

130138

FLNA
Filamin-A

1

4

High-throughput

0.470

High

130139

FGFR3
Fibroblast growth factor receptor 3

1

13

High-throughput

0.470

High

130143

SYUA
Alpha-synuclein

1

2

High-throughput

0.470

High

130167

APBB2
Amyloid beta precursor protein binding family B member 2

1

1

High-throughput

0.470

High

130175

SHLB1
Endophilin-B1

1

5

High-throughput

0.470

High

130145

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.458

High

101780

F8W8I6
TIA1 cytotoxic granule associated RNA binding protein

1

2

High-throughput

0.445

High

130159

ICE2
Little elongation complex subunit 2

1

2

Small-scale

0.445

High

130170

MED10
Mediator of RNA polymerase II transcription subunit 10

1

1

High-throughput

0.445

High

130171

RN181
E3 ubiquitin-protein ligase RNF181

1

1

Small-scale

0.439

High

48176

ESYT2
Extended synaptotagmin-2

1

4

High-throughput

0.437

High

110770

H7BXI1
Extended synaptotagmin 2

1

6

High-throughput

0.407

High

130163

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.316

High

130166

NICA
Nicastrin

1

0

High-throughput

0.279

Low

130176

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.279

Low

130135

GELS
Gelsolin

1

0

High-throughput

0.268

Low

130136

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.268

Low

130140

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.268

Low

130141

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.268

Low

130148

PSN2
Presenilin-2

1

0

High-throughput

0.268

Low

130157

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

130144

AQP2
Aquaporin-2

1

0

Small-scale

0.251

Low


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Last updated: 15 Jul 2024