Protein: SIKE1
Suppressor of IKBKE 1 (Suppressor of IKK-epsilon)

Gene: SIKE1
Organism: Homo sapiens
Interactions: 64
UniProt ID: Q9BRV8

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
GO:0031267 - small GTPase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1310709

FGOP2
FGFR1 oncogene partner 2

3

1

High-throughput

0.871

High

1022862

STRN3
Striatin-3

8

7

High-throughput

0.754

High

672270

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

6

3

High-throughput

0.737

High

215265

STRN
Striatin

5

7

High-throughput

0.722

High

915270

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

5

3

High-throughput

0.722

High

930973

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

4

3

High-throughput

0.704

High

1310712

STK26
Serine/threonine-protein kinase 26

4

13

High-throughput

0.699

High

1310721

STK24
Serine/threonine-protein kinase 24

4

13

High-throughput

0.699

High

1137702

STRP1
Striatin-interacting protein 1

3

4

High-throughput

0.675

High

1310704

PDC10
Programmed cell death protein 10

3

1

High-throughput

0.675

High

1310717

STRP2
Striatin-interacting protein 2

3

4

High-throughput

0.675

High

1061871

SLMAP
Sarcolemmal membrane-associated protein

5

8

High-throughput

0.659

High

1310719

PHOCN
MOB-like protein phocein

4

2

High-throughput

0.645

High

907143

PRS8
26S proteasome regulatory subunit 8

2

1

High-throughput

0.628

High

1310707

STRN4
Striatin-4

3

6

High-throughput

0.619

High

1310718

T3JAM
TRAF3-interacting JNK-activating modulator

3

7

High-throughput

0.613

High

1310716

TNIK
TRAF2 and NCK-interacting protein kinase

2

16

High-throughput

0.611

High

131600

STK25
Serine/threonine-protein kinase 25

3

13

High-throughput

0.609

High

1120638

ZC21C
Zinc finger C2HC domain-containing protein 1C

3

1

High-throughput

0.607

High

770676

TXLNA
Alpha-taxilin

2

1

High-throughput

0.606

High

1233709

KIF2B
Kinesin-like protein KIF2B

2

0

High-throughput

0.602

High

1310708

EXOC1
Exocyst complex component 1

2

0

High-throughput

0.602

High

672466

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

2

3

High-throughput

0.601

High

1184464

CENPQ
Centromere protein Q

2

0

High-throughput

0.580

High

1293237

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1310715

SCOC
Short coiled-coil protein

2

0

High-throughput

0.580

High

1310703

SIKE1
Suppressor of IKBKE 1

1

1

High-throughput

0.575

High

584463

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

1

High-throughput

0.574

High

1232446

TXLNB
Beta-taxilin

2

1

High-throughput

0.553

High

876664

ELL
RNA polymerase II elongation factor ELL

1

1

High-throughput

0.536

High

1145665

ICE2
Little elongation complex subunit 2

1

1

High-throughput

0.536

High

1189141

CC186
Coiled-coil domain-containing protein 186

1

1

High-throughput

0.536

High

1198953

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

1

1

High-throughput

0.536

High

1203191

RASF3
Ras association domain-containing protein 3

1

2

High-throughput

0.536

High

1310705

RABE2
Rab GTPase-binding effector protein 2

1

2

High-throughput

0.536

High

1310710

ABI2
Abl interactor 2

1

2

High-throughput

0.536

High

1310720

MRCKB
Serine/threonine-protein kinase MRCK beta

1

2

High-throughput

0.536

High

416690

S10A6
Protein S100-A6

1

0

High-throughput

0.513

High

827831

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.513

High

1221989

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.513

High

1283631

EXOC4
Exocyst complex component 4

1

0

High-throughput

0.513

High

1305046

TTC1
Tetratricopeptide repeat protein 1

1

0

High-throughput

0.513

High

888294

MYPR
Myelin proteolipid protein

1

1

High-throughput

0.489

High

1137460

RAIN
Ras-interacting protein 1

1

1

High-throughput

0.489

High

1310713

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1310714

TBK1
Serine/threonine-protein kinase TBK1

1

1

Small-scale

0.479

High

839092

EMD
Emerin

1

0

Small-scale

0.458

High

1298506

DOCK7
Dedicator of cytokinesis protein 7

1

0

High-throughput

0.458

High

72975

B4DR80
non-specific serine/threonine protein kinase

1

13

High-throughput

0.445

High

324869

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

15

High-throughput

0.437

High

1051062

ICT1
Large ribosomal subunit protein mL62

1

1

High-throughput

0.437

High

110872

H7C5G9
Sarcolemma associated protein

1

7

High-throughput

0.407

High

111360

J3KS15
Large ribosomal subunit protein mL62

1

1

High-throughput

0.407

High

1126412

NHSL2
NHS-like protein 2

1

2

High-throughput

0.407

High

269480

STX11
Syntaxin-11

4

0

High-throughput

0.364

High

1237108

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

0

High-throughput

0.328

High

203465

MTG8R
Protein CBFA2T2

2

0

High-throughput

0.316

High

942556

CTG1B
Cancer/testis antigen 1

2

0

High-throughput

0.316

High

794460

BTD
Biotinidase

1

0

High-throughput

0.279

Low

1167516

ZY11A
Protein zyg-11 homolog A

1

0

High-throughput

0.279

Low

1231919

AGGF1
Angiogenic factor with G patch and FHA domains 1

1

0

High-throughput

0.279

Low

1310706

ASH1L
Histone-lysine N-methyltransferase ASH1L

1

0

High-throughput

0.279

Low

1310711

DAPLE
Protein Daple

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024