Protein: BIP
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)

Gene: BIP, Hspa5
Organism: Mus musculus
Interactions: 66
UniProt ID: P20029

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005576 - extracellular region
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

627489

DJB11
DnaJ homolog subfamily B member 11

2

20

Small-scale

0.790

High

627471

DNJC1
DnaJ homolog subfamily C member 1

2

20

Small-scale

0.768

High

465803

ENPL
Endoplasmin

2

12

Small-scale

0.754

High

627493

DJC10
DnaJ homolog subfamily C member 10

1

20

Small-scale

0.618

High

627496

HYOU1
Hypoxia up-regulated protein 1

1

19

Small-scale

0.618

High

627452

BIP
Endoplasmic reticulum chaperone BiP

1

15

Small-scale

0.575

High

627483

TTC23
Tetratricopeptide repeat protein 23

1

2

High-throughput

0.553

High

627465

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

12

High-throughput

0.536

High

627470

MKS1
Tectonic-like complex member MKS1

1

2

High-throughput

0.536

High

627484

AHI1
Jouberin

1

20

High-throughput

0.536

High

551378

A4
Amyloid-beta precursor protein

1

5

Small-scale

0.515

High

236988

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

8

Small-scale

0.501

High

204853

ATF6B
Cyclic AMP-dependent transcription factor ATF-6 beta

1

4

Small-scale

0.500

High

420080

PRIO
Major prion protein

1

0

Small-scale

0.493

High

627478

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

4

High-throughput

0.489

High

627498

NPHP1
Nephrocystin-1

1

1

High-throughput

0.489

High

81814

ILDR2
Immunoglobulin-like domain-containing receptor 2

1

1

Small-scale

0.479

High

104682

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

9

Small-scale

0.479

High

108450

G3X9H5
Huntingtin

1

5

High-throughput

0.479

High

237409

SGMR1
Sigma non-opioid intracellular receptor 1

1

3

Small-scale

0.479

High

618507

ANDR
Androgen receptor

1

20

Small-scale

0.479

High

627453

MYD88
Myeloid differentiation primary response protein MyD88

1

7

Small-scale

0.479

High

627454

GRIA2
Glutamate receptor 2

1

2

Small-scale

0.479

High

627456

BRAF
Serine/threonine-protein kinase B-raf

1

18

High-throughput

0.479

High

627461

NPHP4
Nephrocystin-4

1

5

High-throughput

0.479

High

627462

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

13

High-throughput

0.479

High

627463

1433Z
14-3-3 protein zeta/delta

1

16

High-throughput

0.479

High

627464

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

627466

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.479

High

627472

TFE3
Transcription factor E3

1

5

High-throughput

0.479

High

627476

FACD2
Fanconi anemia group D2 protein homolog

1

5

High-throughput

0.479

High

627477

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

16

High-throughput

0.479

High

627479

CBAR1
CBY1-interacting BAR domain-containing protein 1

1

1

High-throughput

0.479

High

627485

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.479

High

627486

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

13

Small-scale

0.479

High

627488

EED
Polycomb protein EED

1

11

High-throughput

0.479

High

627490

ERP44
Endoplasmic reticulum resident protein 44

1

17

Small-scale

0.479

High

627491

Q9D2V3
Progranulin

1

4

High-throughput

0.479

High

627494

SET
Protein SET

1

5

Small-scale

0.479

High

627497

CNPY2
Protein canopy homolog 2

1

1

Small-scale

0.479

High

627499

FZR1
Fizzy-related protein homolog

1

20

High-throughput

0.479

High

92784

PDIA2
Protein disulfide-isomerase A2

1

18

Small-scale

0.445

High

313290

INVS
Inversin

1

10

High-throughput

0.445

High

464494

PDIA4
Protein disulfide-isomerase A4

1

17

Small-scale

0.445

High

627457

RAB17
Ras-related protein Rab-17

1

8

High-throughput

0.445

High

627460

ERP29
Endoplasmic reticulum resident protein 29

1

16

Small-scale

0.445

High

627468

IASPP
RelA-associated inhibitor

1

14

Small-scale

0.445

High

627469

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

13

High-throughput

0.445

High

627481

PGLT1
Protein O-glucosyltransferase 1

1

3

Small-scale

0.445

High

627482

FTM
Protein fantom

1

17

High-throughput

0.445

High

627495

SDF2L
Stromal cell-derived factor 2-like protein 1

1

2

Small-scale

0.445

High

59578

A2AM57
Inversin

1

10

High-throughput

0.437

High

97563

E9PV60
WD repeat and FYVE domain containing 4

1

12

High-throughput

0.437

High

398089

CFAD
Complement factor D

1

11

High-throughput

0.437

High

627455

LIPC
Hepatic triacylglycerol lipase

1

1

Small-scale

0.437

High

627458

SOX2
Transcription factor SOX-2

1

6

High-throughput

0.437

High

627459

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

Small-scale

0.437

High

627467

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

8

High-throughput

0.437

High

627474

TEDC2
Tubulin epsilon and delta complex protein 2

1

2

High-throughput

0.437

High

627475

SPOP
Speckle-type POZ protein

1

4

High-throughput

0.437

High

627487

ELF5
ETS-related transcription factor Elf-5

1

8

High-throughput

0.437

High

627492

MZB1
Marginal zone B- and B1-cell-specific protein

1

0

Small-scale

0.426

High

97879

CECR2
Chromatin remodeling regulator CECR2

1

16

Small-scale

0.407

High

627473

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

5

High-throughput

0.407

High

627480

RD3
Protein RD3

1

1

Small-scale

0.407

High


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Last updated: 11Aug2025