Protein: FXL14
F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14)

Gene: FXL14, FBXL14
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q8N1E6

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0019005 - SCF ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

928983

SKP1
S-phase kinase-associated protein 1

5

20

High-throughput

0.931

High

1041088

CUL1
Cullin-1

5

20

Small-scale

0.930

High

862076

DAPK1
Death-associated protein kinase 1

1

5

High-throughput

0.692

High

326708

SNAI1
Zinc finger protein SNAI1

4

4

Small-scale

0.692

High

1184903

CSN6
COP9 signalosome complex subunit 6

3

1

High-throughput

0.675

High

1230769

DICER
Endoribonuclease Dicer

3

1

Small-scale

0.667

High

1105467

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

20

High-throughput

0.647

High

324960

QORL1
Quinone oxidoreductase-like protein 1

2

3

High-throughput

0.628

High

728633

PPM1A
Protein phosphatase 1A

2

1

High-throughput

0.628

High

897271

CSN2
COP9 signalosome complex subunit 2

2

3

High-throughput

0.628

High

1024182

CSN1
COP9 signalosome complex subunit 1

2

2

High-throughput

0.628

High

1230761

CSN5
COP9 signalosome complex subunit 5

2

1

High-throughput

0.628

High

1230768

CSN3
COP9 signalosome complex subunit 3

2

2

High-throughput

0.628

High

1230770

SGT1
Protein SGT1 homolog

2

11

High-throughput

0.628

High

1230771

DAAM1
Disheveled-associated activator of morphogenesis 1

2

2

High-throughput

0.628

High

1079100

STK11
Serine/threonine-protein kinase STK11

1

4

Small-scale

0.618

High

1161001

AAGAB
Alpha- and gamma-adaptin-binding protein p34

2

0

High-throughput

0.602

High

1230767

CSN7A
COP9 signalosome complex subunit 7a

2

0

High-throughput

0.602

High

1056296

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

2

1

High-throughput

0.574

High

1230759

TTC9C
Tetratricopeptide repeat protein 9C

2

4

High-throughput

0.574

High

1230765

SC11C
Signal peptidase complex catalytic subunit SEC11C

2

1

High-throughput

0.574

High

921640

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

3

High-throughput

0.536

High

980627

TLE1
Transducin-like enhancer protein 1

1

5

High-throughput

0.536

High

1230760

STYX
Serine/threonine/tyrosine-interacting protein

1

1

High-throughput

0.536

High

1230762

FEM1A
Protein fem-1 homolog A

1

3

High-throughput

0.536

High

931539

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

1

High-throughput

0.489

High

73158

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

9

High-throughput

0.479

High

432050

HS90A
Heat shock protein HSP 90-alpha

1

10

High-throughput

0.479

High

438345

HS90B
Heat shock protein HSP 90-beta

1

12

High-throughput

0.479

High

921337

RBX1
E3 ubiquitin-protein ligase RBX1

1

7

Small-scale

0.479

High

1034926

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

4

High-throughput

0.479

High

1054240

HES1
Transcription factor HES-1

1

1

Small-scale

0.479

High

1162511

Q6PK50
Heat shock protein HSP 90-beta

1

12

High-throughput

0.479

High

1230764

AASD1
Alanyl-tRNA editing protein Aarsd1

1

1

High-throughput

0.479

High

1230763

MTA3
Metastasis-associated protein MTA3

1

1

Small-scale

0.445

High

1062460

SPCS2
Signal peptidase complex subunit 2

2

0

High-throughput

0.328

High

1168309

PPR21
Protein phosphatase 1 regulatory subunit 21

2

0

High-throughput

0.328

High

1017591

FSTL1
Follistatin-related protein 1

1

0

High-throughput

0.279

Low

1230772

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

1076847

TWST1
Twist-related protein 1

1

0

Small-scale

0.249

Low

1230766

CDCP1
CUB domain-containing protein 1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024