Protein: SGT1
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)

Gene: SGT1, SUGT1
Organism: Homo sapiens
Interactions: 236
UniProt ID: Q9Y2Z0

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0007051 - spindle organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

432387

HS90A
Heat shock protein HSP 90-alpha

8

20

Small-scale

0.755

High

233024

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

6

19

Small-scale

0.736

High

416734

S10A6
Protein S100-A6

1

2

Small-scale

0.724

High

1218202

CEP97
Centrosomal protein of 97 kDa

4

10

Small-scale

0.694

High

1069573

TEBP
Prostaglandin E synthase 3

1

8

High-throughput

0.691

High

1335141

CYBP
Calcyclin-binding protein

1

2

High-throughput

0.691

High

1031308

SKP2
S-phase kinase-associated protein 2

3

12

High-throughput

0.675

High

1294493

LRCH3
DISP complex protein LRCH3

3

20

High-throughput

0.675

High

929128

SKP1
S-phase kinase-associated protein 1

3

1

Small-scale

0.674

High

1331817

RNF41
E3 ubiquitin-protein ligase NRDP1

3

10

Small-scale

0.667

High

1068152

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.656

High

1377002

NOD1
Nucleotide-binding oligomerization domain-containing protein 1

3

13

Small-scale

0.650

High

538450

ENPL
Endoplasmin

3

20

Small-scale

0.640

High

1053266

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

2

20

High-throughput

0.628

High

1073356

RSU1
Ras suppressor protein 1

2

20

High-throughput

0.628

High

1124873

LRC10
Leucine-rich repeat-containing protein 10

2

20

High-throughput

0.628

High

1230770

FXL14
F-box/LRR-repeat protein 14

2

11

High-throughput

0.628

High

1292316

AURKB
Aurora kinase B

2

8

High-throughput

0.628

High

1330487

DSN1
Kinetochore-associated protein DSN1 homolog

2

0

Small-scale

0.619

High

1297965

NALP4
NACHT, LRR and PYD domains-containing protein 4

2

13

Small-scale

0.612

High

1347600

NALP2
NACHT, LRR and PYD domains-containing protein 2

2

13

Small-scale

0.612

High

1035065

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

2

20

High-throughput

0.611

High

1305151

DNJC7
DnaJ homolog subfamily C member 7

2

19

High-throughput

0.611

High

299536

KLH18
Kelch-like protein 18

3

4

High-throughput

0.609

High

1110328

AL1L2
Mitochondrial 10-formyltetrahydrofolate dehydrogenase

3

3

High-throughput

0.609

High

1288119

LRC39
Leucine-rich repeat-containing protein 39

3

20

High-throughput

0.609

High

934575

CSK21
Casein kinase II subunit alpha

2

10

Small-scale

0.602

High

529942

CFTR
Cystic fibrosis transmembrane conductance regulator

2

3

High-throughput

0.601

High

1335701

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

2

13

Small-scale

0.601

High

1354643

FXL17
F-box/LRR-repeat protein 17

2

8

High-throughput

0.601

High

438644

HS90B
Heat shock protein HSP 90-beta

2

20

Small-scale

0.595

High

1158413

PMF1
Polyamine-modulated factor 1

2

1

Small-scale

0.595

High

714473

HSP74
Heat shock 70 kDa protein 4

1

20

Small-scale

0.589

High

1161854

FBX38
F-box only protein 38

2

0

Small-scale

0.585

High

385766

NTRK1
High affinity nerve growth factor receptor

2

15

High-throughput

0.584

High

504993

HSP7C
Heat shock cognate 71 kDa protein

2

20

Small-scale

0.584

High

961333

HSF1
Heat shock factor protein 1

2

2

Small-scale

0.584

High

1268989

AKAP1
A-kinase anchor protein 1, mitochondrial

2

3

High-throughput

0.584

High

1356350

FBXL4
F-box/LRR-repeat protein 4

2

11

Small-scale

0.584

High

1160590

LRC8B
Volume-regulated anion channel subunit LRRC8B

2

20

High-throughput

0.574

High

1238561

LRC57
Leucine-rich repeat-containing protein 57

2

20

High-throughput

0.574

High

164158

ARHGA
Rho guanine nucleotide exchange factor 10

2

2

High-throughput

0.571

High

497851

TAU
Microtubule-associated protein tau

2

12

High-throughput

0.571

High

1357816

SHOC2
Leucine-rich repeat protein SHOC-2

2

18

High-throughput

0.571

High

1294764

NSL1
Kinetochore-associated protein NSL1 homolog

2

0

Small-scale

0.569

High

1327295

MIS12
Protein MIS12 homolog

2

0

Small-scale

0.569

High

861997

PLK1
Serine/threonine-protein kinase PLK1

1

4

Small-scale

0.561

High

932928

EF1A1
Elongation factor 1-alpha 1

1

4

Small-scale

0.561

High

1296589

WDR90
WD repeat-containing protein 90

2

6

High-throughput

0.558

High

1356544

ITBP2
Integrin beta-1-binding protein 2

1

12

Small-scale

0.553

High

118804

AIP
AH receptor-interacting protein

1

19

High-throughput

0.536

High

127404

IPO5
Importin-5

1

3

High-throughput

0.536

High

153193

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

10

High-throughput

0.536

High

204089

HTRA2
Serine protease HTRA2, mitochondrial

1

4

High-throughput

0.536

High

258256

DNJB6
DnaJ homolog subfamily B member 6

1

13

High-throughput

0.536

High

609711

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

6

High-throughput

0.536

High

682085

AKT1
RAC-alpha serine/threonine-protein kinase

1

4

High-throughput

0.536

High

812836

PA24A
Cytosolic phospholipase A2

1

4

High-throughput

0.536

High

848513

IRAK1
Interleukin-1 receptor-associated kinase 1

1

3

High-throughput

0.536

High

858686

PPP5
Serine/threonine-protein phosphatase 5

1

11

High-throughput

0.536

High

862135

DAPK1
Death-associated protein kinase 1

1

14

High-throughput

0.536

High

960430

CDK16
Cyclin-dependent kinase 16

1

3

High-throughput

0.536

High

972614

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

19

High-throughput

0.536

High

983278

UBE3A
Ubiquitin-protein ligase E3A

1

10

High-throughput

0.536

High

1023260

FLII
Protein flightless-1 homolog

1

11

High-throughput

0.536

High

1033605

ILK
Integrin-linked protein kinase

1

4

High-throughput

0.536

High

1038342

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

11

High-throughput

0.536

High

1039956

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.536

High

1047649

CDK13
Cyclin-dependent kinase 13

1

8

High-throughput

0.536

High

1053458

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

5

High-throughput

0.536

High

1054692

RBM39
RNA-binding protein 39

1

8

High-throughput

0.536

High

1068457

CDK10
Cyclin-dependent kinase 10

1

5

High-throughput

0.536

High

1085556

MK06
Mitogen-activated protein kinase 6

1

4

High-throughput

0.536

High

1105502

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

10

High-throughput

0.536

High

1120219

LRC23
Leucine-rich repeat-containing protein 23

1

13

High-throughput

0.536

High

1172971

PHLP2
PH domain leucine-rich repeat-containing protein phosphatase 2

1

17

High-throughput

0.536

High

1221912

DDX60
Probable ATP-dependent RNA helicase DDX60

1

4

High-throughput

0.536

High

1233570

MINK1
Misshapen-like kinase 1

1

8

High-throughput

0.536

High

1254142

MK15
Mitogen-activated protein kinase 15

1

4

High-throughput

0.536

High

1288060

HDA11
Histone deacetylase 11

1

4

High-throughput

0.536

High

1301469

ERBIN
Erbin

1

18

High-throughput

0.536

High

1301728

TESK2
Dual specificity testis-specific protein kinase 2

1

1

High-throughput

0.536

High

1312326

LRRC1
Leucine-rich repeat-containing protein 1

1

19

High-throughput

0.536

High

1319452

STRAB
STE20-related kinase adapter protein beta

1

10

High-throughput

0.536

High

1332523

RPAP3
RNA polymerase II-associated protein 3

1

19

High-throughput

0.536

High

1342596

PAR6A
Partitioning defective 6 homolog alpha

1

8

High-throughput

0.536

High

1344982

LATS2
Serine/threonine-protein kinase LATS2

1

5

High-throughput

0.536

High

1356955

CNOT6
CCR4-NOT transcription complex subunit 6

1

15

High-throughput

0.536

High

1357072

HSF4
Heat shock factor protein 4

1

2

High-throughput

0.536

High

1376981

RUVB2
RuvB-like 2

1

7

High-throughput

0.536

High

1377412

M3K2
Mitogen-activated protein kinase kinase kinase 2

1

5

High-throughput

0.536

High

1299049

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

13

Small-scale

0.529

High

147579

SOCS6
Suppressor of cytokine signaling 6

1

6

High-throughput

0.515

High

813864

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

1071637

LRC41
Leucine-rich repeat-containing protein 41

1

0

High-throughput

0.513

High

1334017

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.513

High

1357804

HPS5
BLOC-2 complex member HPS5

1

0

High-throughput

0.513

High

723271

PE2R4
Prostaglandin E2 receptor EP4 subtype

1

2

High-throughput

0.494

High

131623

STK25
Serine/threonine-protein kinase 25

1

13

High-throughput

0.489

High

264524

LRCH4
Leucine-rich repeat and calponin homology domain-containing protein 4

1

20

High-throughput

0.489

High

794445

GRK6
G protein-coupled receptor kinase 6

1

10

High-throughput

0.489

High

1050095

SCRIB
Protein scribble homolog

1

14

High-throughput

0.489

High

1093520

LRC36
Leucine-rich repeat-containing protein 36

1

16

High-throughput

0.489

High

1153762

STYK1
Tyrosine-protein kinase STYK1

1

7

High-throughput

0.489

High

1155927

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

17

High-throughput

0.489

High

1198849

ADCK1
AarF domain-containing protein kinase 1

1

1

High-throughput

0.489

High

1204013

LRC28
Leucine-rich repeat-containing protein 28

1

20

High-throughput

0.489

High

1234882

TTC9C
Tetratricopeptide repeat protein 9C

1

20

High-throughput

0.489

High

1241333

CAMKV
CaM kinase-like vesicle-associated protein

1

13

High-throughput

0.489

High

1253371

LRC20
Leucine-rich repeat-containing protein 20

1

20

High-throughput

0.489

High

1264052

MYO3B
Myosin-IIIb

1

2

High-throughput

0.489

High

1286394

ULK4
Serine/threonine-protein kinase ULK4

1

7

High-throughput

0.489

High

1293200

TONSL
Tonsoku-like protein

1

10

Small-scale

0.489

High

1315133

TSSK1
Testis-specific serine/threonine-protein kinase 1

1

6

High-throughput

0.489

High

1334127

LRC40
Leucine-rich repeat-containing protein 40

1

18

High-throughput

0.489

High

1345644

NRBP2
Nuclear receptor-binding protein 2

1

9

High-throughput

0.489

High

1377291

SIK3
Serine/threonine-protein kinase SIK3

1

2

High-throughput

0.489

High

1377311

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

20

High-throughput

0.489

High

1377485

RPKL1
Ribosomal protein S6 kinase-like 1

1

9

High-throughput

0.489

High

211284

BUB3
Mitotic checkpoint protein BUB3

1

5

High-throughput

0.481

High

611530

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

12

High-throughput

0.481

High

1173288

PAXI1
PAX-interacting protein 1

1

4

High-throughput

0.481

High

148123

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

7

High-throughput

0.479

High

156651

PPE2
Serine/threonine-protein phosphatase with EF-hands 2

1

13

High-throughput

0.479

High

229122

PRKN
E3 ubiquitin-protein ligase parkin

1

15

High-throughput

0.479

High

256921

NPHP4
Nephrocystin-4

1

1

High-throughput

0.479

High

262131

PEX14
Peroxisomal membrane protein PEX14

1

1

High-throughput

0.479

High

272774

OFD1
Centriole and centriolar satellite protein OFD1

1

7

High-throughput

0.479

High

279363

DNJB5
DnaJ homolog subfamily B member 5

1

15

High-throughput

0.479

High

295431

RECQ4
ATP-dependent DNA helicase Q4

1

7

High-throughput

0.479

High

302058

TRI37
E3 ubiquitin-protein ligase TRIM37

1

13

High-throughput

0.479

High

302697

ARHGF
Rho guanine nucleotide exchange factor 15

1

1

High-throughput

0.479

High

325466

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

5

High-throughput

0.479

High

348300

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.479

High

411902

LCK
Tyrosine-protein kinase Lck

1

2

High-throughput

0.479

High

428513

TBB5
Tubulin beta chain

1

8

High-throughput

0.479

High

554111

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

570207

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.479

High

591159

BTF3
Transcription factor BTF3

1

4

High-throughput

0.479

High

649176

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

8

High-throughput

0.479

High

652668

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

681659

DNJA1
DnaJ homolog subfamily A member 1

1

11

High-throughput

0.479

High

729389

VGFR3
Vascular endothelial growth factor receptor 3

1

7

High-throughput

0.479

High

780358

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

809045

YAP1
Transcriptional coactivator YAP1

1

17

High-throughput

0.479

High

886435

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

14

Small-scale

0.479

High

887219

DJB13
DnaJ homolog subfamily B member 13

1

14

High-throughput

0.479

High

897008

ARP2
Actin-related protein 2

1

8

High-throughput

0.479

High

897154

ACTZ
Alpha-centractin

1

9

High-throughput

0.479

High

909366

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

914478

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

918784

H2B1C
Histone H2B type 1-C/E/F/G/I

1

13

High-throughput

0.479

High

933675

TBA4A
Tubulin alpha-4A chain

1

10

High-throughput

0.479

High

957670

ZXDA
Zinc finger X-linked protein ZXDA

1

3

Small-scale

0.479

High

994533

QOR
Quinone oxidoreductase

1

1

High-throughput

0.479

High

1026593

RFA4
Replication protein A 30 kDa subunit

1

6

High-throughput

0.479

High

1027869

DUS8
Dual specificity protein phosphatase 8

1

2

High-throughput

0.479

High

1030047

TIF1B
Transcription intermediary factor 1-beta

1

10

High-throughput

0.479

High

1072489

ELOB
Elongin-B

1

1

High-throughput

0.479

High

1074442

STIL
SCL-interrupting locus protein

1

1

High-throughput

0.479

High

1121150

GLE1
mRNA export factor GLE1

1

2

High-throughput

0.479

High

1131898

CE170
Centrosomal protein of 170 kDa

1

5

High-throughput

0.479

High

1158602

L2GL2
LLGL scribble cell polarity complex component 2

1

6

High-throughput

0.479

High

1175267

TBA1A
Tubulin alpha-1A chain

1

9

Small-scale

0.479

High

1185107

DET1
DET1 homolog

1

3

High-throughput

0.479

High

1200777

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1244582

NUP43
Nucleoporin Nup43

1

10

High-throughput

0.479

High

1245933

DNJB8
DnaJ homolog subfamily B member 8

1

18

High-throughput

0.479

High

1254323

BICD2
Protein bicaudal D homolog 2

1

5

High-throughput

0.479

High

1262173

DNJA4
DnaJ homolog subfamily A member 4

1

11

High-throughput

0.479

High

1271086

SYMPK
Symplekin

1

1

High-throughput

0.479

High

1272718

CSN5
COP9 signalosome complex subunit 5

1

5

High-throughput

0.479

High

1287441

OPTN
Optineurin

1

8

High-throughput

0.479

High

1297144

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

16

High-throughput

0.479

High

1303879

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.479

High

1304969

NECD
Necdin

1

3

High-throughput

0.479

High

1306408

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

6

High-throughput

0.479

High

1310867

TRI56
E3 ubiquitin-protein ligase TRIM56

1

13

High-throughput

0.479

High

1319034

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

10

Small-scale

0.479

High

1326798

WWTR1
WW domain-containing transcription regulator protein 1

1

15

High-throughput

0.479

High

1334053

WDR76
WD repeat-containing protein 76

1

8

High-throughput

0.479

High

1343009

NLRC4
NLR family CARD domain-containing protein 4

1

13

Small-scale

0.479

High

1343225

TRI36
E3 ubiquitin-protein ligase TRIM36

1

15

High-throughput

0.479

High

1343398

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

High-throughput

0.479

High

1347895

MKS1
Tectonic-like complex member MKS1

1

1

High-throughput

0.479

High

1349353

CNOT2
CCR4-NOT transcription complex subunit 2

1

1

High-throughput

0.479

High

1354940

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1356172

ANC2
Anaphase-promoting complex subunit 2

1

5

High-throughput

0.479

High

1357559

FAF1
FAS-associated factor 1

1

3

High-throughput

0.479

High

1377484

MTCH2
Mitochondrial carrier homolog 2

1

10

High-throughput

0.479

High

1222181

AMN1
Protein AMN1 homolog

1

9

High-throughput

0.470

High

200712

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.458

High

324689

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

532654

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

854842

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

High-throughput

0.458

High

896271

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

1199624

LBN
Limbin

1

0

High-throughput

0.458

High

1330321

CENPH
Centromere protein H

1

0

Small-scale

0.458

High

349746

RASH
GTPase HRas

1

5

High-throughput

0.445

High

1153469

PKHA7
Pleckstrin homology domain-containing family A member 7

1

15

High-throughput

0.445

High

231015

CE104
Centrosomal protein of 104 kDa

1

1

High-throughput

0.437

High

434317

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

19

High-throughput

0.437

High

490041

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

1

High-throughput

0.437

High

608205

FGFR4
Fibroblast growth factor receptor 4

1

15

High-throughput

0.437

High

609621

FGFR3
Fibroblast growth factor receptor 3

1

14

High-throughput

0.437

High

721839

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

825607

LMAN1
Protein ERGIC-53

1

4

High-throughput

0.437

High

884621

RAB25
Ras-related protein Rab-25

1

2

High-throughput

0.437

High

1002079

ARL16
ADP-ribosylation factor-like protein 16

1

2

High-throughput

0.437

High

1172363

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.437

High

1197691

NEK8
Serine/threonine-protein kinase Nek8

1

7

High-throughput

0.437

High

1204872

GOLI
E3 ubiquitin-protein ligase RNF130

1

4

High-throughput

0.437

High

1240484

POC1A
POC1 centriolar protein homolog A

1

7

High-throughput

0.437

High

1272909

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

13

High-throughput

0.437

High

1346564

DJC11
DnaJ homolog subfamily C member 11

1

17

High-throughput

0.437

High

1349245

MTCH1
Mitochondrial carrier homolog 1

1

7

High-throughput

0.437

High

1349873

SEP10
Septin-10

1

2

High-throughput

0.437

High

1354265

KS6B2
Ribosomal protein S6 kinase beta-2

1

4

High-throughput

0.437

High

1356391

DJC12
DnaJ homolog subfamily C member 12

1

12

High-throughput

0.437

High

831829

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.408

High

3309

A0A0S2Z547
Rho guanine nucleotide exchange factor 15 isoform 1

1

1

High-throughput

0.407

High

1071591

L2GL1
Lethal(2) giant larvae protein homolog 1

1

1

High-throughput

0.407

High

1356393

FBXL2
F-box/LRR-repeat protein 2

1

11

High-throughput

0.407

High

1377483

LRC42
Leucine-rich repeat-containing protein 42

3

0

High-throughput

0.347

High

1262869

NEUR4
Sialidase-4

2

0

High-throughput

0.328

High

947189

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.279

Low

1241924

ARRD4
Arrestin domain-containing protein 4

1

0

High-throughput

0.279

Low

1309780

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.279

Low

1152212

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1158004

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

0

High-throughput

0.249

Low

1284279

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

1298684

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

1316836

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

1329330

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

1342518

DLRB1
Dynein light chain roadblock-type 1

1

0

High-throughput

0.249

Low

230674

KATIP
Katanin-interacting protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024