HitPredict

Interactor 1: A0A0S2Z4Q8 (A0A0S2Z4Q8)
Protein phosphatase 1 regulatory subunit 12B isoform 2
Gene: PPP1R12B

Interactor 2: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	26871637
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Hs			1 327
+	Hs
		906447 ASPP2_HUMAN (9-166): 1.34e-41: 150: 32.08		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		906424 Q05BL1_HUMAN (9-166): 2.69e-41: 149: 32.08		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		225133 MYPT2_HUMAN (1-180): 1.91e-35: 132: 18.85		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Mm
		93784 E9QJU8_MOUSE (11-166): 4.54e-42: 151: 33.12		PP1A_MOUSE (1-326): 0: 576: 88.49
+	Hs
		905884 ASPP2_HUMAN (9-166): 1.34e-41: 150: 32.08		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		905849 Q05BL1_HUMAN (9-166): 2.69e-41: 149: 32.08		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		738001 BARD1_HUMAN (55-183): 1.11e-42: 153: 34.62		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		737795 ASPP2_HUMAN (9-166): 1.34e-41: 150: 32.08		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		737760 Q05BL1_HUMAN (9-166): 2.69e-41: 149: 32.08		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		906617 RAI14_HUMAN (62-179): 3.1e-31: 120: 21.85		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		161348 MYPT1_HUMAN (15-175): 1.34e-30: 119: 19.82		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		905838 ANK2_HUMAN (62-183): 4.35e-38: 140: 29.51		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Gg
		907234 MYPT1_CHICK (1-175): 5.01e-30: 117: 19.50		PP1B_CHICK (1-327): 0: 597: 100.00
+	Hs
		225132 MYPT2_HUMAN (1-180): 1.91e-35: 132: 18.85		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Mm
		906293 MYPT2_MOUSE (1-180): 1.07e-34: 130: 18.85		PP1A_MOUSE (1-326): 0: 576: 88.49
+	Hs
		225129 MYPT2_HUMAN (1-180): 1.91e-35: 132: 18.85		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		161347 MYPT1_HUMAN (15-175): 1.34e-30: 119: 19.82		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		738091 RAI14_HUMAN (62-179): 3.1e-31: 120: 21.85		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		161322 MYPT1_HUMAN (15-175): 1.34e-30: 119: 19.82		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		862021 DAPK1_HUMAN (12-183): 1.66e-47: 167: 23.73		PP2AA_HUMAN (8-303): 2.77e-176: 491: 45.79